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| 1 | Cyclooxygenase-2 and epithelial growth factor receptor up-regulation during progression of Barrett's esophagus to adenocarcinoma显示文摘瞄准:在整个 Barretts 食管的前进调查 cyclooxygenase-2 (COX-2 ) 和上皮的生长因素受体(EGFR ) 的表示() 。方法:COX-2 和 EGFR 蛋白质表情被使用免疫检测组织化学的方法。详细 cytomorphological 改变的 A 是坚定的。COX-2 和 EGFR 表示的区域被使用计算机成像系统确定。结果:COX-2 和 EGFR 的表情与前进一起增加了从到食管腺癌(EAC ) 。积极关联在 COX-2 表示和 EGFR 表示之间被发现。结论:COX-2 和 EGFR 可能在逐步的前进从是合作的到 EAC,从而导致致癌作用。 | Yan Li John M Wo Mukunda B Ray Whitney Jones Ruifeng R Su Susan Ellis Robert C G Martin | 2006 | World Journal of Gastroenterology2006，12，6： | 14 |
| 2 | Evaluation of Burkholdderia cepacia strains:Root colonization of Catharanthus roseus and in vitro inhibition of selected of soil borne fungal pathogens 显示文摘 | Mansour B Martin A D Kenneth E C | 1999 | Proceedings of the Oklahoma Academy of Science1999，79，： | 3 |
| 3 | Nanomaterial-based Li-ion battery electrodes显示文摘 | LIN C MARTIN C R SCROSATI B | 2001 | J Power Sources2001，9798，： | 2 |
| 4 | Parameters of a severe disease course in ulcerative colitis显示文摘AIM:To detect high risk patients with a progressive disease course of ulcerative colitis(UC) requiring immunosuppressive therapy(IT).METHODS:A retrospective,multicenter analysis of 262 UC patients from eight German tertiary inflammatory bowel disease centres was performed.Patients were divided into two groups depending on the patients need to initiate immunosuppressive therapy in the disease course.A comparison between the two groups was made with regard to demographics,clinical and laboratory parameters obtained within three months after UC diagnosis and the response to first medical therapy.Using this data,a prognostic model was established to predict the individual patients probability of requiring an immunosuppressive therapy.RESULTS:In 104(39.7%) out of 262 patients,UC therapy required an immunosuppressive treatment.Patients in this group were significantly younger at time of diagnosis(HR = 0.981 ± 0.014 per year,P = 0.009),and required significantly more often a hospitalisation(HR = 2.5 ± 1.0,P < 0.001) and a systemic corticosteroid therapy at disease onset(HR = 2.4 ± 0.8,P < 0.001),respectively.Response to steroid treatment was significantly different between the two groups of patients(HR = 5.2 ± 3.9 to 50.8 ± 35.6 compared to no steroids,P = 0.016 to P < 0.001).Furthermore,in the IT group an extended disease(HR = 3.5 ± 2.4 to 6.1 ± 4.0 compared to proctitis,P = 0.007 to P = 0.001),anemia(HR = 2.2 ± 0.8,P < 0.001),thrombocytosis(HR = 1.9 ± 1.8,P = 0.009),elevated C-reactive protein(CRP)(HR = 2.1 ± 0.9,P < 0.001),and extraintestinal manifestations in the course of disease(HR = 2.6 ± 1.1,P = 0.004) were observed.Six simple clinical items were used to establish a prognostic model to predict the individual risk requiring an IT.This probability ranges from less than 2% up to 100% after 5 years.Using this,the necessity of an immunosuppressive therapy can be predicted in 60% of patients.Our model can determine the need for an immunosuppressive drug therapy or if a 'watch and wait' approach is reasonable already early in the treatment course of UC.CONCLUSION:Using six simple clinical parameters,we can estimate the patients individual risk of developing a progressive disease course. | Andreas Stallmach Luisa Nickel Thomas Lehmann Bernd Bokemeyer Martin Bürger Dietrich Hüppe Wolfgang Kruis Susanna Nikolaus Jan C Preiss Andreas Sturm Niels Teich Carsten Schmidt | 2014 | World Journal of Gastroenterology2014，20，35： | 2 |
| 5 | Fretting wear and cracking in sintered metal matrix composites显示文摘 | Martin B Vincent L Wright C S | 2001 | Wear2001，248，1： | 2 |
| 6 | 显示文摘 | Raveau B Martin C Maignao A | 1998 | J Alloys and Comp1998，，： | 2 |
| 7 | 显示文摘 | Maignan A Martin C Raveau B | 1997 | Condens Matter1997，102，： | 2 |
| 8 | Comparison of fluticasone propionate aqueous nasal spray and oral montelukast for the treatment of seasonal allergic rhinitis symptoms显示文摘 | MARTIN B G ANDREWS C P VAN BAVEL J H | 2006 | Ann Allergy Asthma Immunol2006，96，： | 1 |
| 9 | The effects of moisture on the flammability characteristics of textile materials显示文摘 | Miller B Martin J R Goswami B C | 1975 | Textile Research Journal1975，45，： | 1 |
| 10 | Relationship of psychological factors to frequent symptomatic ventricular arrhythmia 显示文摘 | Katz C Martin RD Landa B | 1985 | Am J Med1985，78，： | 1 |
| 11 | Detection and quantitation of HER-2 gene amplification and protein expression in breast carcinoma显示文摘 | Bofin AM Ytterhus B Martin C | 2004 | Am J Clin Pathol2004，122，1： | 1 |
| 12 | Aerial application methods for increasing spray deposition on wheat heads 显示文摘 | Fritz B K Hoffmann W C Martin D E | 2007 | Applied Engineering in Agriculture2007，23，6： | 1 |
| 13 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 14 | An empirical study of applied game theory: Transmission constrained Cournot behavior显示文摘 | Lance B C Ross B Martin L B | 2002 | IEEE Transactions on Power Systems2002，17，1： | 1 |
| 15 | Random sample consensus: A paradigm for model fitting with application to image analysis and automated cartography显示文摘 | Martin A F Robert C B | 1981 | Communications of the ACM:Graphics and Image Processing1981，24，6： | 1 |
| 16 | Multicenter evaluation of AMPLICOR and automated COBAS AMPLICOR CT/NG tests for Neisseria gonorrhoeae显示文摘 | Martin DH Cammarata C Van Der Pol B | 2000 | J Clin Microbiol2000，38，10： | 1 |
| 17 | Bacterial elicitation and evasion of plant innate immunity 显示文摘 | Abramovitch R B Anderson J C Martin G B | 2006 | Nat Rev Mol Cell Biol2006，7，8： | 1 |
| 18 | The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis 显示文摘 | Mascaux C Iannino N Martin B | 2005 | Br J Cancer2005，92，1： | 1 |
| 19 | Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘 | Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R | 2009 | Journal of Bacteriology2009，191，16： | 1 |
| 20 | Pharmacokinetics of long-term propofol infusion used for sedation in ICU patients显示文摘 | Albanese J Martin C Lacarelle B | | 0，，： | 1 |
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