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| 1 | 皮质下小血管病诊断的共识声明显示文摘血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病(Binswanger's disease, BD)的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组,存在缺氧缺血、腔隙性梗死和炎症,它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物,这将有助于诊断以及将来协作性治疗试验的患者选择。 | Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师 张劼 陈涵丰 俞娅美 徐子奇 罗本燕 | 2016 | 国际脑血管病杂志2016，24，6： | 18 |
| 2 | Near-infrared fluorescence sentinel lymph node detection in gastric cancer: A pilot study显示文摘AIM: To investigate feasibility and accuracy of nearinfrared fluorescence imaging using indocyanine green: nanocolloid for sentinel lymph node(SLN) detection in gastric cancer.METHODS: A prospective, single-institution, phaseI feasibility trial was conducted. Patients suffering from gastric cancer and planned for gastrectomy were included. During surgery, a subserosal injection of 1.6 m L ICG:Nanocoll was administered around the tumor. NIR fluorescence imaging of the abdominal cavity was performed using the Mini-FLARE? NIR fluorescence imaging system. Lymphatic pathways and SLNs were visualized. Of every detected SLN, the corresponding lymph node station, signal-to-background ratio and histopathological diagnosis was determined. Patients underwent standard-of-care gastrectomy. Detected SLNs outside the standard dissection planes were also resected and evaluated.RESULTS: Twenty-six patients were enrolled. Four patients were excluded because distant metastases were found during surgery or due to technical failure of the injection. In 21 of the remaining 22 patients, at least 1 SLN was detected by NIR Fluorescence imaging(mean 3.1 SLNs; range 1-6). In 8 of the 21 patients, tumor-positive LNs were found. Overall accuracy of the technique was 90%(70%-99%; 95%CI), which decreased by higher p T-stage(100%, 100%, 100%, 90%, 0% for respectively Tx, T1, T2, T3, T4 tumors). All NIR-negative SLNs were completely effaced by tumor. Mean fluorescence signal-to-background ratio of SLNs was 4.4(range 1.4-19.8). In 8 of the 21 patients, SLNs outside the standard resection plane were identified, that contained malignant cells in 2 patients.CONCLUSION: This study shows successful use of ICG:Nanocoll as lymphatic tracer for SLN detection in gastric cancer. Moreover, tumor-containing LNs outside the standard dissection planes were identified. | Quirijn RJG Tummers Leonora SF Boogerd Wobbe O de Steur Floris PR Verbeek Martin C Boonstra Henricus JM Handgraaf John V Frangioni Cornelis JH van de Velde Henk H Hartgrink Alexander L Vahrmeijer | 2016 | World Journal of Gastroenterology2016，22，13： | 9 |
| 3 | Sequence stratigraphy of experimental strata under known conditions of differential subsidence and variable base level显示文摘 | Martin J Paola C Abreu V | 2009 | AAPG Bulletin2009，93，4： | 1 |
| 4 | Modeling charge transport in composite solar cells显示文摘 | Martin C M Burlakov V M | 2006 | Solar Energy Mater Solar Cells2006，90，： | 1 |
| 5 | qPCR for quantitative detection of tyramine-producing bacteria in dairy products显示文摘 | LADERO V MARTINEZ N MARTIN M C | 2010 | Food Research International2010，43，1： | 1 |
| 6 | Acetylcholinesterase inhibitors ameliorate behavioral deficits in the Tg2576 mouse model of Alzheimer' s disease显示文摘 | Dong H Csemansky C A Martin M V | | 0，，： | 1 |
| 7 | Particulate air pollution and daily mortality on Utah's wasatch front 显示文摘 | Arden P C Randy W H Martin G V | 1999 | Environmental Health Perspectives1999，107，7： | 1 |
| 8 | A review of production planning and scheduling models in the semiconductor industry part Ⅱ: shop-floor control 显示文摘 | Uzsoy R L C Martin V L A | 1994 | IIE Transactions1994，26，5： | 1 |
| 9 | Meniscal tears: pathologic correlation with MR imaging 显示文摘 | Stoller D W Martin C Crues J V 3rd | 1987 | Radiology1987，163，3： | 1 |
| 10 | Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘 | Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R | 2009 | Journal of Bacteriology2009，191，16： | 1 |
| 11 | Relationship between total transit time and fecal quality in dogs differing body size显示文摘 | Hernot D C Blourge V C Martin L J | | 0，，： | 1 |
| 12 | Multistage expansion planning for active distribution networks under demand and distributed generation uncertainties显示文摘 | BORGES C L T MARTINS V F | 2012 | International Journal of Electrical Power Energy Systems2012，36，1： | 1 |
| 13 | A decadal satellite analysis of the origins and impacts of smoke in Colorado 显示文摘 | MARTIN M V HEALD C L FORD B | 2013 | Atmospheric Chemistry Physics2013，13，3： | 1 |
| 14 | Search Strategies for Feeder Bus Network Design Problem显示文摘 | Martins C L Pato M V | 1998 | European Journal of Operation Research1998，106，： | 1 |
| 15 | Boron-containing novolac resins as flame retardant materials显示文摘 | MARTIN C RONDA J C CADIZ V | 2006 | Polymer Degradation and Stability2006，91，4： | 1 |
| 16 | Modelling brittle failure of rock显示文摘 | HAJIABDOLMAJID V KAISER P K MARTIN C D | 2002 | International Journal of Rock Mechanics and Mining Sciences2002，39，6： | 1 |
| 17 | Active distribution network integrated planning incorporating distributed generation and load response uncertainties显示文摘 | MARTINS V F BORGES C L T | 2011 | IEEE Trans on Power Systems2011，26，4： | 1 |
| 18 | Reverse Engineering of Geometric Models-an Introduction显示文摘 | Martin R R Jordan C | 1997 | Computer-Aided Design1997，29，4： | 1 |
| 19 | Template synthesis of graphitic nanotubules显示文摘 | Parthasarathy R V Phani K L Martin C R | 1995 | Adv Mater1995，7，： | 1 |
| 20 | Development of novel flame-retardant thermosets based on boron-modified phenol-formaldehyde resins 显示文摘 | Martin C Rinda J C Crdiz V | 2006 | Journal of Polymer Science Part A : Polymer Chemistry2006，44，11： | 1 |
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