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| 1 | Efficacy and safety of liquid nitrogen cryotherapy for treatment of Barrett's esophagus显示文摘AIM To evaluate the efficacy and safety of liquid nitrogen cryotherapy as a primary or rescue treatment for BE,with and without dysplasia,or intramucosal adenocarcinoma (IMC).METHODS This was a retrospective,single-center study carried out in a tertiary care center including 45 patients with BE who was treatment-na?ve or who had persistent intestinal metaplasia(IM),dysplasia,or IMC despite prior therapy.Barrett's mucosa was resected via EMR when clinically appropriate,then patients underwent cryotherapy until eradication or until deemed to have failed treatment.Surveillance biopsies were taken at standard intervals.RESULTS From 2010 through 2014,33 patients were studied regarding the efficacy of cryotherapy.Overall,29 patients (88%) responded to cryotherapy,with 84% having complete regression of all dysplasia and cancer.Complete eradication of cancer and dysplasia was seen in 75% of subjects with IMC; the remaining two subjects did not respond to cryotherapy.Following cryotherapy,15 patients with high-grade dysplasia (HGD) had 30% complete regression,50% IM,and 7% low-grade dysplasia (LGD); one subject had persistent HGD.Complete eradication of dysplasia occurred in all 5 patients with LGD.In 5 patients with IM,complete regression occurred in 4,and IM persisted in one.In 136 cryotherapy sessions amongst 45 patients,adverse events included chest pain (1%),stricture (4%),and one gastrointestinal bleed in a patient on dual antiplatelet therapy who had previously undergone EMR.CONCLUSION Cryotherapy is an efficacious and safe treatment modality for Barrett's esophagus with and without dysplasia or intramucosal adenocarcinoma. | Kristen Suchniak-Mussari Charles E Dye Matthew T Moyer Abraham Mathew Thomas J McGarrity Eileen M Gagliardi Jennifer L Maranki John M Levenick | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 4 |
| 2 | Parametric study on the combined thermal and hydraulic performance of single phase micro pin-fin heat sinks part I: Square and circle geometries 显示文摘 | JOHN T J MATHEW B HEGAB H | 2010 | International Journal of Thermal Sciences2010，49，11： | 1 |
| 3 | Clinicopathological correlates of CD56 expression in multiple myeloma: a unique entity显示文摘 | Mathew P Ahmann G J Witzig T E | 1995 | Br J Haematol1995，90，： | 1 |
| 4 | Palladium catalyzed Suzuki cross-coupling reactions in ambient temperature ionic liquids显示文摘 | MATHEWS C J SMITH P J WELTON T | 2000 | Chemical Communications2000，14，： | 1 |
| 5 | A strip loaded dielectric resonator antenna for circular polarisation 显示文摘 | KUMAR A V P HAMSAKUTTY V YOHANNAN J MATHEW K T | 2006 | Microwave and Optical Technology Letters2006，48，7： | 1 |
| 6 | The use of combined bladder and epispadias repair in boys with classic bladder exstrophy: outcomes, complications and consequences显示文摘 | Baird A D Mathews R T Gearhart J P | 2005 | J Urol2005，174，： | 1 |
| 7 | Generalized p- values and generalized confidence regions for the multivariate Behrens-Fisher problem and MANOVA 显示文摘 | Gamage J Mathew T Weerahandi S | 2004 | J Multivariate Anal2004，88，： | 1 |
| 8 | Removal of phosphate by the green seaweed Ulva lactuca in a small-scale sewage treatment plant (Ios Island, Aegean Sea, Greece) 显示文摘 | Panagiotis T Daniel D Mathew D J | 2010 | Journal of Applied Phycology2010，22，3： | 1 |
| 9 | Effect of ionic strength and protein concentration on the transport of proteins through chitosan/polystyrene sul- fonate multilayer membrane显示文摘 | Mathew J Aravindakumar C T Aravind U K | 2008 | J Membr Sci2008，325，： | 1 |
| 10 | Annual summary of vital statistics :2008 显示文摘 | Mathews T J Minino A M Osterman M J | 2011 | Pediatrics2011，127，1： | 1 |
| 11 | Aldosterone promotes proximal tubular cell apoptosis:role of oxidative stress显示文摘 | Patni H Mathew J T Luan L | 2007 | Am J Physiol Renal Physiol2007，293，4： | 1 |
| 12 | Media violence exposure and frontal lobe activation measured by functional mag- netic resonance imaging in aggressive and nonaggres- sive adolescents 显示文摘 | Mathews V P Kronenberger W G Wang Y Lurito J T Lowe M J Dunn D W | 2005 | J Comput Assist Tomo2005，29，： | 1 |
| 13 | The inclusion of in-plane stresses in delamination criteria显示文摘 | Mathew T F Anthony J V | 2001 | Journal of Compostie Material2001，35，15： | 1 |
| 14 | Diphenylpyraline, a histamine HI receptor antagonist, has psychostimulant properties 显示文摘 | Lapa G Mathews T Harp J | 2005 | Eur J Pharmacol2005，506，： | 1 |
| 15 | cross-coupling reactions in ambient temperature ionic liquids: evidence for theimportance of palladium imidazolylidene complexes显示文摘 | McLachlan F Mathews C Palladium-catalyzed Suzuki J Smith P J Welton T | 2003 | Organometallics2003，22，： | 1 |
| 16 | Parametric study onthe combined thermal and hydraulic performance of singlephase micro pin fin heat sink partⅠ:square and circlegeometries显示文摘 | JOHN T J MATHEW B HEGAB H | 2010 | International Journal of Thermal Science2010，49，11： | 1 |
| 17 | Infant mortality statistics from 2005 period linked birth/infant death data set 显示文摘 | Mathews T J MacDorman M F | 2008 | Natl Vital Stat Rep2008，57，2： | 1 |
| 18 | Primary breast cancer in men:clinical,imaging,and pathologic findings in 57 patients显示文摘 | Mathew J Perkins G H Stephens T | 2008 | AJR2008，191，6： | 1 |
| 19 | The inclusion of in plane stresses in delamination criteria显示文摘 | Mathew T F Anthony J V | 2001 | Journal of Composite Materials2001，35，15： | 1 |
| 20 | Palladium catalysed Suzuki cross-coupling reactions in ambient temperature ionic liquids显示文摘 | Mathews C J Smith P J Wehon T | 2000 | Cbem Commun2000，14，： | 1 |
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