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| 1 | Surveillance for hepatocellular carcinoma in chronic liver disease:Evidence and controversies显示文摘Primary liver cancer is the sixth most common cancer in the world and the third cause of cancer-related death.Hepatocellular carcinoma(HCC)represents more than90%of primary liver cancers and generally occurs in patients with underlying chronic liver disease such as viral hepatitis,hemochromatosis,primary biliary cirrhosis and non-alcoholic steatohepatitis.Especially cirrhotic patients are at risk of HCC and regular surveillance could enable early detection and therapy,with potentially improved outcome.We here summarize existing evidence for surveillance including ultrasound,other radiological modalities and various serum biomarkers,and current international guideline recommendations for surveillance.Ultrasound andα-fetoprotein(alone or in combination)are most frequently used for surveillance,but their sensitivities and specificities are still far from perfect,and evidence for surveillance remains weak and controversial.Various other potential surveillance tools have been tested,including serum markers as des-carboxyprothrombin,lectin-boundα-fetoprotein,and(most recently)circulating TIE2-expressing monocytes,and radiological investigations such as computed tomographyscan or magnetic resonance imaging-scan.Although early results appear promising,these tools have generally been tested in diagnostic rather than surveillance setting,and in most cases,no detailed information is available on their cost-effectiveness.For the near future,it remains important to define those patients with highest risk of HCC and most benefit from surveillance,and to restrict surveillance to these categories. | Suzanne van Meer Robert A de Man Peter D Siersema Karel J van Erpecum | 2013 | World Journal of Gastroenterology2013，19，40： | 10 |
| 2 | Inhi- bition of Denitrification Activity but not of mRNA Induction in Paracoccus denitrificans by Nitrite at a Suboptimal pH 显示文摘 | BAUMANN B VAN DER MEER J R SNOZZI M | 1997 | Antonie van Leeuwenhoek1997，72，： | 1 |
| 3 | The relation between morphology and hydrotreating activity for supported MoS2 particles 显示文摘 | HENSEN E J M KOOYMAN P J Van der MEER Y Van der KRAAN A M de BEER V H J Van VEEN J A R Van SANTEN R A | 2001 | J Catal2001，199，2： | 1 |
| 4 | Energy ex- penditure and balance following pediatric intensive care unit admis- sion: a longitudinal study of critically ill children 显示文摘 | Oosterveld M J Van Der Kuip M De Meer K | 2006 | Pediatr Crit Care Med2006，7，2： | 1 |
| 5 | Cytomegalovirus as a cause of anterior uveitis in immunocompetent patients显示文摘 | van Boxtel LA van der Lelij A van der Meer J | 2007 | Ophthalmology2007，114，： | 1 |
| 6 | Wave Runup on Smooth and Rock Slopes of Coastal Structures显示文摘 | J W Van de Meer C M Stain | 1992 | Journal Waterway Port Coastal and Ocean Eng ASCE1992，118，5： | 1 |
| 7 | Inhibition of denitrification activity but not of mRNA induction in Paracoccus denitrificans by nitrite at a suboptimal pH显示文摘 | Baumann B van der Meer J R Snozzi M | 1997 | Antonie van Leeuwenhoek1997，72，3： | 1 |
| 8 | Singular points atberm breakwaters: scale effects, rear, round headand longshore transport 显示文摘 | van der Meer J W Veldman J J | 1992 | Coastal Engineering1992，17，34： | 1 |
| 9 | Dietary cheese whey protein protects rats against mild dextran sulfate sodium-induced colitis:role ofmucin and microbiota显示文摘 | Sprong R C Schonewille A J van der Meer R | 2010 | J Dairy Sci2010，93，4： | 1 |
| 10 | Assessment of soil n-alkane δD and branched tetraether membrane lipid distributions as tools for paleoelevation reconstruction 显示文摘 | Peterse F van der Meer M T J Schouten S | 2009 | Biogeosciences Discuss2009，6，： | 1 |
| 11 | Genetics and Breeding of Cultivated Seaweeds显示文摘 | Patwary M U van der Meer J P | 1992 | The Korean Journal of Phycology1992，7，2： | 1 |
| 12 | The relation between morphology and hydrotreating activity for supported MoS2 particles显示文摘 | Hensen E J M Kooyman P J Meer Y V | | 0，，： | 1 |
| 13 | Multi- and hyperspectral geologic remote sensing: A review显示文摘 | van der Meer F D van der Werff H M A van Ruitenbeek F J A | 2012 | International Journal of Applied Earth Observation and Geoinformation2012，14，1： | 1 |
| 14 | Polyphosphate accumulation in the senescing mushroom Agaricus bisporus显示文摘 | Braaksma A Meer P V Schaap D J | 1996 | Post-harvest Biology and Technology1996，8，： | 1 |
| 15 | KIR gene and KIR ligand analysis to predict graft rejection after renal transplantation显示文摘 | Kreijveld E Van der Meer A Tijssen H J | 2007 | Transplantation2007，84，8： | 1 |
| 16 | Comparison of EDTA and EDDS as potential soil amendments for enhanced phytoextraction of heavy metal显示文摘 | Meers E Ruttens A Hopgood M J | 2005 | Chemosphere2005，58，： | 1 |
| 17 | Flow patterns in the square cross-section riser of a circulating fluidized bed and the effect of riser exit design显示文摘 | E H van der Meer Thorpe R B Davidson J F | 2000 | Chemical Engineering Science2000，55，19： | 1 |
| 18 | Comparison of EDTA and EDDS aspotential soil amendments forenhanced phytoextraction of heavy metals显示文摘 | Meers E Ruttens A Hopgood M J | 2005 | Chemosphere2005，58，： | 1 |
| 19 | Map Manager QTX,cross- platform software for genetic mapping 显示文摘 | Manly K F Cudmore R H Meer J M | 2001 | Mamm Genome2001，12，12： | 1 |
| 20 | Wave transmission at low-crested structures显示文摘 | Kees d'Angremond Jentsje W Van Der Meer Rutger J De Jong | 1996 | Coastal Engineering1996，1，25： | 1 |
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