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| 1 | Embryonal rhabdomyosarcoma in the maxillary sinus with orbital involvement in a pediatric patient:Case report显示文摘This report presents a case of embryonal rhabdomyosarcoma(e RMS) located in the left maxillary sinus and invading the orbital cavity in a ten-year-old male patient who was treated at a referral hospital.The images provided from the computed tomography showed a heterogeneous mass with soft-tissue density,occupying part of the left half of the face inside the maxillary sinus,and infiltrating and destroying the bone structure of the maxillary sinus,left orbit,ethmoidal cells,nasal cavity,and sphenoid sinus.An analysis of the histological sections revealed an undifferentiated malignant neoplasm infiltrating the skeletal muscle tissue.The immunohistochemical analysis was positive for the antigens:MyoD 1,myogenin,desmin,and Ki67(100% positivity in neoplastic cells),allowing the identification of the tumour as an eR MS.The treatment protocol included initial chemotherapy followed by radiotherapy and finally surgery.The total time of the treatment was nine months,and in 18-mo of follow-up period did not show no local recurrences and a lack of visual impairment. | Ana Carolina Rodrigues de Melo Tácio Candeia Lyra Isabella Lima Arrais Ribeiro Alexandre Rolim da Paz Paulo Rogério Ferreti Bonan Ricardo Dias de Castro Ana Maria Gondim Valen?a | 2017 | World Journal of Clinical Cases2017，5，12： | 3 |
| 2 | Proton nuclear magnetic resonance-based metabonomic models for non-invasive diagnosis of liver fibrosis in chronic hepatitis C:Optimizing the classification of intermediate fibrosis显示文摘AIM To develop metabonomic models(MMs), using 1 H nuclear magnetic resonance(NMR) spectra of serum, to predict significant liver fibrosis(SF: Metavir ≥ F2), advanced liver fibrosis(AF: METAVIR ≥ F3) and cirrhosis(C: METAVIR = F4 or clinical cirrhosis) in chronic hepatitis C(CHC) patients. Additionally, to compare the accuracy of the MMs with the aspartate aminotransferase to platelet ratio index(APRI) and fibrosis index based on four factors(FIB-4). METHODS Sixty-nine patients who had undergone biopsy in the previous 12 mo or had clinical cirrhosis were included. The presence of any other liver disease was a criterion for exclusion. The MMs, constructed using partial least squares discriminant analysis and linear discriminant analysis formalisms, were tested by cross-validation, considering SF, AF and C. RESULTS Results showed that forty-two patients(61%) presented SF, 28(40%) AF and 18(26%) C. The MMs showed sensitivity and specificity of 97.6% and 92.6% to predict SF; 96.4% and 95.1% to predict AF; and 100% and 98.0% to predict C. Besides that, the MMs correctly classified all 27(39.7%) and 25(38.8%) patients with intermediate values of APRI and FIB-4, respectively. CONCLUSION The metabonomic strategy performed excellently in predicting significant and advanced liver fibrosis in CHC patients, including those in the gray zone of APRI and FIB-4, which may contribute to reducing the need for these patients to undergo liver biopsy. | Andrea Dória Batista Carlos Jonnatan Pimentel Barros Tássia Brena Barroso Carneiro Costa Michele Maria Goncalves de Godoy Ronaldo Dionísio Silva Joelma Carvalho Santos Mariana Montenegro de Melo Lira Norma ThoméJucá Edmundo Pessoa de Almeida Lopes Ricardo Oliveira Silva | 2018 | World Journal of Hepatology2018，10，1： | 2 |
| 3 | Role of myofibroblasts, macrophages, transforming growth factor-beta endothelin, angiotensin- Ⅱ , and fibronectin in the progression of tubulointerstitial nephritis induced by gentamicin 显示文摘 | Geleilete T J Melo G C Costa R S | 2002 | J Nephrol2002，15，6： | 1 |
| 4 | Remote intracerebral hematoma after rt-PA in acute stroke显示文摘 | Falcao F Canhao P Melo T | 2008 | Cerebrovasc Dis2008，25，2： | 1 |
| 5 | Hamack Inequality for a Class of Degenerate Elliptic Operator 显示文摘 | FERNANDES J D GROISMAN J MELO S T | 2003 | Zeitschrift fur Analysis Und Ihre Anwendungen2003，22，1： | 1 |
| 6 | Biofouling in Water Systems 显示文摘 | Melo L F Bott T R | 1997 | Experimental Thermal and Fluid Science1997，14，4： | 1 |
| 7 | Cytogenetic studies in peripheral blood of bovines afflicted by pap- illomatosis显示文摘 | Melo T C Diniz N Campos S R et ai | 2011 | Vet Comp Oncol2011，9，4： | 1 |
| 8 | Post-stroke apathy:an exploratory longitudinal study显示文摘 | Caeiro L Ferro JM Pinho E Melo T | 2013 | Cerebrovasc Dis2013，35，6： | 1 |
| 9 | An experimental analysis of adiabatic capillary tubes 显示文摘 | Melo C Ferreira R T S Neto C B | 1999 | Applied Thermal Engineering1999，19，6： | 1 |
| 10 | Facility location and supply chain management A review显示文摘 | Melo M T Nickel S Saldanha-da-Gama F | 2009 | European Journal of Operational Re-search2009，196，2： | 1 |
| 11 | An optical device to measure in-line residence time distribution curves during extrusion显示文摘 | Melo T J A Canevarolo S V | 2002 | Polym Engng Sci2002，42，1： | 1 |
| 12 | Salt-sensitive hypertension in ANP knockout mice is prevented by AT1 receptor antagonist losartan 显示文摘 | MELO L G VERESS A T CHONG C K a al | 1999 | Am J Physiol1999，277，32： | 1 |
| 13 | Microstructural Evolution at the Initial Stages of Continuous Annealing of Cold Rolled Dual phase Steels 显示文摘 | Rocha R O Melo T M F Pereloma E V | 2005 | Materials Science and Engineering2005，391，12： | 1 |
| 14 | BRU59-21, a second-generation 99mTc-labeled 2-nitroimidazole for imaging hypoxia in rumors显示文摘 | Melo T Duncan J Ballinger JR | 2000 | J Nucl Med2000，41，： | 1 |
| 15 | Harnack inquality for a class of degenerate elliptics operators显示文摘 | FERNANDES J D GROISMAN J MELO S T | 2003 | Zeitschrift fur analysis Und Ihre Anwendungen2003，22，1： | 1 |
| 16 | The Bone Morphogenetic Protein Antagonist Gremlin Promotes Vascular Smooth Muscle Cell Apoptosis显示文摘 | Maciel T T Melo R S Campos A H | | 0，，04： | 1 |
| 17 | Epicardial radiofrequency applications: in vitro and in vivo studies on human atrial myocardium显示文摘 | Santiago T Melo J Gouveia RH | 2003 | Eur J Cardiothorac Surg2003，24，4： | 1 |
| 18 | Are brief or recurrent transient global amnesia of epileptic origin?显示文摘 | MELO TP FERROJM PAIVA T | 1994 | Neurol Neurosurg Psychiatry1994，57，： | 1 |
| 19 | Vascular risk factors for perimesencephalic nonaneurysmal subarachnoid hemorrhage显示文摘 | Canhao P Faleao F Pinto e Melo T | 1999 | J Neurol1999，246，： | 1 |
| 20 | An ex- perimental study on defrost heaters applied to frost- free household refrigerators 显示文摘 | MELO C KNABBEN F T PEREIRA P V | 2013 | Applied Thermal En- gineering2013，51，12： | 1 |
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