|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hypoglycemic and anti-hyperglycemic study of Gynura procumbens leaf extracts显示文摘Objective:To study the antidiabetic activity of Gynura procumbens(G.procumbens)used in the traditional management of diabetes in Southern Asia.Methods:G.procumbens leaves were extracted sequentially with graded percentage of ethanol in water(95%,75%,50%,25%and 0%),and the extracts were tested for antidiabetic activity using acute(7 h),subcutaneous glucose tolerance test and sub-chronic(14 d)test in non-diabetic and streptozotocin-induced diabetic rats.The extracts were further subjected to phytochemical studies.Results:In acute dose(1 g/kg),the extracts significantly lowered fasting blood glucose(FBG)in streptozotocin-induced diabetic rats(P<0.05).However,the FBG-lowering effect of the 25%extract compared to the other extracts,was rapid(47%after 2 h)and the highest:53%,53%and 60%in the 3rd,5th,and 7th h,respectively(P<0.05),comparable only to the effect of metformin.Furthermore,the extracts suppressed peak FBG in subcutaneous glucose tolerance test,but only the 0%and 25%extracts,and metformin sustained the decrease until the 90th min(P<0.05).Moreover,in the 14 days study,the 25%extract exerted the highest FBG-lowering effect,namely 49.38%and 65.43%on days 7 and 14,respectively(P<0.05),similar to the effect of metformin(46.26%and 65.42%).Total flavanoid and phenolic contents in the extracts were found to decrease with increase in polarity of extraction solvents.The composition of reference compounds(chlorogenic acid,rutin,astragalin and kaempferol-3-O-nrtinoside)followed a similar trend.Conclusions:G.procumbens contains antidiabetic principles,most extracted in 25%ethanol.Interaction among active components appears to determine the antidiabetic efficacy,achieved likely by a metformin-like mechanism. | Khalid Algariri Kuong Y Meng Item J Atangwho Mohd Z Asmawi Amirin Sadikun Vikneswaran Murugaiyah Norhyati Ismail | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，5： | 4 |
| 2 | Comparison of the Mechanical Properties and Interracial Interactions Between Talc, Kaolin, and Calcium Carbonate Filled Polypropylene Composites显示文摘 | Leong Y W Bakar M B Mohd Z A | 2004 | Journal of Applied Polymer Science2004，91，5： | 1 |
| 3 | Effects of Filler Treatments on the Mechanical, Flow, Thermal, and Morphological Properties of Talc and Calcium Carbonate Filled Polypropylene Hybrid Composites 显示文摘 | Leong Y W Bakar M B Mohd Z A | 2005 | Journal of Applied Polymer Science2005，98，1： | 1 |
| 4 | Pathogenicity of Rigidoporus microporus and Phellinus noxius against four major plantation tree species in Peninsular Malaysia显示文摘 | A Mohd Farid SS Lee Z Maziah | 2009 | Journal of Tropical Forest Science2009，21，4： | 1 |
| 5 | Effect of silane-based coupling agents and acrylic acid based compatibilizers on mechanical properties of oil palm empty fruit bunch filled high-density polyethylene composites显示文摘 | MOHD ISHAK Z A AMINULLAH A ISMAIL H | 1998 | J Appl Polym Sci1998，68，13： | 1 |
| 6 | Surface-activated nanosilica treated with silane coupling agents/polypropylene composites:Mechanical,morphological,and thermal studies显示文摘 | Lin 0 H Akil H M Mohd Ishak Z A | 2011 | Polymer Composites2011，32，10： | 1 |
| 7 | In- fluence of SEBS-g-MA on morphology, mechanical and ther- mal properties of PA6/PP/organoclay nanocomposites 显示文摘 | KUSMONO ISHAK MOHD Z A CHOW W S | 2008 | Eur Polym J2008，44，： | 1 |
| 8 | Weighing the evidence of low glycemic index dietary intervention for the management of gestational diabetes mellitus: an Asian perspective 显示文摘 | Mohd Yusof B N Firouzi S Mohd Shariff Z | 2014 | Int J Food Sci Nutr2014，65，2： | 1 |
| 9 | Evaluation on Antibacterial Activity of Lactobacillus acidophilus Strains Isolated from Honey 显示文摘 | Mustafa A M Hassan Z Mohd N H | 2012 | American Journal of Applied Sciences2012，9，6： | 1 |
| 10 | The incidence of postoperative pain after canal preparation of open teeth using two irrigation regimes显示文摘 | MOHD SULONG M Z | 1989 | Int Endool1989，22，： | 1 |
| 11 | A new design of piezoelectric driven compliant-based microgripper for micromanipulation显示文摘 | MOHD N M Z SHIRINZADEH B TIAN Y L | 2009 | Mechanism and Machine Theory2009，44，12： | 1 |
| 12 | 显示文摘 | Lim K L K Mohd Ishak Z A Ishiaku U S | 2006 | Journal of Applied Polymer Science2006，100，5： | 1 |
| 13 | Synthesis and properties of layered organic-in- organic hybrid material: Zn-A1 layered double hydroxide-dioctyl sulfosuccinate nanocomposite 显示文摘 | Mohd Z H Tan K H | 2000 | J Nanopart Res2000，2，： | 1 |
| 14 | Flammability and mechanical properties of wood flour- filled polypropylene composites显示文摘 | Abu Bakar M B Mohd Ishak Z A Mat Taib R | 2010 | Journal of Applied Polymer Science2010，116，5： | 1 |
| 15 | Total qualityman- agement and theory of constraints implementation in malaysian automotive suppliers: a survey result 显示文摘 | RAIMONA Z H MOHD Y S | 2006 | Total Quality Management & Business Excellence2006，17，8： | 1 |
| 16 | Techniques for vibration control of a flexible robot manipulator 显示文摘 | Mohamed Z Chee A K Mohd H A W I | 2006 | Robotica2006，24，4： | 1 |
| 17 | The incidence of postoperative pain after canal preparation of open teeth using two irrigation regimes显示文摘 | Mohd Sulong M Z | 1989 | Endod J1989，22，5： | 1 |
| 18 | Characterization of talc/calcium carbonate filled polypropylene hybrid composites weathered in a natural environment 显示文摘 | Y W Leong M B Abu Bakar Z A Mohd Ishak | 2004 | Polymer Degradation and Stability2004，83，3： | 1 |
| 19 | Ethylene-oetene copolymer (POE) toughened polyamide 6/polypropylene nanocomposites: Effect of POE maleation 显示文摘 | Wahit M U Hassan A Mohd Ishak Z A | 2009 | Express Polymer Letters2009，3，5： | 1 |
| 20 | Expenmentm investigation to compare the modulus of rupture in high strength self compacting concrete deep beams and high strength concrete normal beams显示文摘 | Mohammad M Mohd Z MohammaO J | 2012 | Construction and Building Materials2012，30，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员