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| 1 | Pollen Tube Growth: a Delicate Equilibrium Between Secretory and Endocytic Pathways显示文摘Although pollen tube growth is a prerequisite for higher plant fertilization and seed production, the processes leading to pollen tube emission and elongation are crucial for understanding the basic mechanisms of tip growth. It was generally accepted that pollen tube elongation occurs by accumulation and fusion of Golgi-derived secretory vesicles (SVs) in the apical region, or clear zone, where they were thought to fuse with a restricted area of the apical plasma membrane (PM), defining the apical growth domain. Fusion of SVs at the tip reverses outside cell wall material and provides new segments of PM. However, electron microscopy studies have clearly shown that the PM incorporated at the tip greatly exceeds elongation and a mechanism of PM retrieval was already postulated in the mid-nineteenth century. Recent studies on endocytosis during pollen tube growth showed that different endocytic pathways occurred in distinct zones of the tube, including the apex, and led to a new hypothesis to explain vesicle accumulation at the tip; namely, that endocytic vesicles contribute substantially to V-shaped vesicle accumulation in addition to SVs and that exocytosis does not involve the entire apical domain. New insights suggested the intriguing hypothesis that modulation between exo-and endocytosis in the apex contributes to maintain PM polarity in terms of lipid/protein composition and showed distinct degradation pathways that could have different functions in the physiology of the cell. Pollen tube growth in vivo is closely regulated by interaction with style molecules. The study of endocytosis and membrane recycling in pollen tubes opens new perspectives to studying pollen tube-style interactions in vivo. | Alessandra Moscatelli Aurora Irene Idilli | 2009 | Journal of Integrative Plant Biology2009，51，8： | 5 |
| 2 | Bmi-1, stem cells and prostate carcinogenesis显示文摘 | David Moscatelli E Lynette Wilson | 2011 | Asian Journal of Andrology2011，13，3： | 3 |
| 3 | 重症医师完成新生儿及儿童床旁超声引导下经皮双腔管体外膜肺氧合置管术:一项回顾性研究显示文摘目的报道重症医师床旁超声引导下经皮双腔管体外膜肺氧合(extracorporeal membrane oxygenation,ECMO)置管的单中心经验。设计回顾性观察性研究。场所一家三级儿童医院的体外膜肺氧合团队。对象2013.1.1~2018.1.1间所有行VV-ECMO治疗的0~14岁患儿。干预措施无。方法和主要结果30名患儿共32次ECMO治疗,纳入时中位年龄2(0~20.5)个月,21次(65.6%)为新生儿(13次,40.6%)或婴幼儿(8次,25.0%)。中位ECMO前氧合指数为66.9(50.0~85.6)。50%患儿出现严重合并症,所有患儿均经皮置管,2例经左侧颈内静脉置管。ECMO对提高pH,SpO2,PaO2及降低PaCO2有效。ECMO前后各值总体来讲存在统计学差异,按置管直径(mm)/颈内静脉外径(mm)比值分层分析(>0.67 or ≤0.67)显示统计学差异仅见于最高比值。3例ECMO发生并发症,2例管端进入右心房,1例未用Avalon管者流速受限。20次(32次中62.5%)置管血管随访或尸检显示开放。置管直径/颈内静脉外径比值≤0.67或>0.67并不影响并发症、颈内静脉闭塞、颅内出血致死以及ECMO撤机30 d病死率。ECMO撤机30 d总体累积性存活率60.0%(95%CI 40~75),比值>0.67者存活率较高(65.0%,95%CI 44~80比25.0%,95%CI 0~60)。结论文中所述技术证实可行,安全且有效,尚需进一步研究。 | Moscatelli A Febbo F Buratti S 方伯梁(译) 钱素云(审校) | 2019 | 中国小儿急救医学2019，26，7： | 3 |
| 4 | Recent developments in the cell biology of basic fibroblast growth factor 显示文摘 | Rifkin DB Moscatelli D | 1989 | J Cell Biol1989，108，1： | 3 |
| 5 | Microtubule Depolymerization Affects Endocytosis and Exocytosis in the Tip and Influences Endosome Movement in Tobacco Pollen Tubes显示文摘种花粉试管的细胞质的极化的组织被肌动朊细丝(AF ) 和微导管(MT ) 的协调功能维持。AF 传送 post-Golgi 能分泌的泡到一些与 plasmamembrane (下午) 的特定的领域熔化的尖端。能分泌的活动被维持房间膜经济并且调整 PM 的 polarizedcomposition 的下午检索平衡,由划分在胫和尖端之间的类脂化合物 / 蛋白质。尽管 AF 在下午 internalizationin 起一个关键作用胫,在 exo-endocytosis 的 MT 的角色需要被描绘。现在的结果证明 theMT 细胞骨架的完整是必要的在尖端控制 exo-endocytosis 事件。自从 nocodazole 为降级从顶在尖端和随后的 migrationof endocytic 泡影响了下午成为主观, MT 聚合在在烟草花粉试管的顶支持 PMinvagination 起一个作用。在顶和胫的 MT depolymerization 与 misallocationof 被联系到 Golgi 仪器并且它早在 Photobleaching 以后再循环到能分泌的 pathway.Fluorescence 恢复的使内在化的下午的显著地更大的数量(捆牢)实验也证明在尖端区域 influencedthe 的 MT depolymerization 在中央领域 exocytosis 评价顶端的 PM.Key 词: | Aurora Irene Idilli Piero Morandini Elisabetta Onelli Simona Rodighiero Marco Caccianiga Alessandra Moscatelli | 2013 | Molecular Plant2013，6，4： | 2 |
| 6 | Soil Microbial Indices As Bio-indicators Of Environmental Changes In A Poplar Plantation 显示文摘 | Moscatelli M C Lagomarsino A Marinari S | 2005 | Ecological Indicators2005，5，： | 1 |
| 7 | Angiogenesie factors stimulate plasminogen activator and collagenase production by capillary endothelial cells显示文摘 | Moscatelli D Gross J Rifkin D | 1981 | J Cell Biol1981，，： | 1 |
| 8 | Resent developments in the cell biology of basic fibroblast growth factor显示文摘 | Rifkin D B Moscatelli D | 1989 | J Cell Biol1989，109，1： | 1 |
| 9 | Soilbiochemical indicators as a tool to assess the short-termimpact of agricultural management on changes in organicC in a Mediterranean environment显示文摘 | Lagomarsino A Moscatelli M C Di Tizio A | 2009 | Ecological Indica-tors2009，9，3： | 1 |
| 10 | Angiogenesis factors stimulate plasminogen activator and collagenase production by capillary endothelial cells 显示文摘 | Gross J Rifkin D | 1981 | J Cell Biol1981，，： | 1 |
| 11 | Recent developments in cell biology of basic fibroblast growth factor显示文摘 | Moscatelli D | 1989 | J Cell Biol1989，109，： | 1 |
| 12 | Lack of ERK activation and cell migration in FGF-2-deficient endothelial cells显示文摘 | Pintucci G Moscatelli D Saponara F | 2002 | FASEB J2002，16，6： | 1 |
| 13 | Evaluation of the Flow Force on a Direct (Single Stage) Proportional Valve by Means of a Computational Fuid Dynamic Analysis显示文摘 | Amirante R Moscatelli P G Catalano L A | | 0，，48： | 1 |
| 14 | Short- and medium-term contrasting effects of nitrogen fertilization on C and N cycling in a poplar plantation soil显示文摘 | M.C. Moscatelli A. Lagomarsino P. De Angelis S. Grego | 2007 | Forest Ecology and Management2007，，3： | 1 |
| 15 | The FGF family of growth factors and oncogenes 显示文摘 | BASILICO C MOSCATELLI D | 1992 | Adv Cancer Res1992，59，： | 1 |
| 16 | Recent developments in the cell biology of basic fibroblast growth factor显示文摘 | Rifkin DB Moscatelli D | 1989 | J Cell Bio11989，109，： | 1 |
| 17 | Lack of ERK activation and cell migration in FGF-2-deficient endothelial cells 显示文摘 | Pintucci G Moscatelli D Saponara F | 2002 | FASEB J2002，16，6： | 1 |
| 18 | Tetradecanoyl phcrbol acetate stimulates latent collagenase production by cultured human endothelial cells显示文摘 | Moscatelli D Jaffe E Rifkin DB | 1980 | Cell1980，20，2： | 1 |
| 19 | Short-and medium-term contrasting effects of nitrogen fertilization on C and N cycling in a poplar plantation soil显示文摘 | Moscatelli M C Lagomarsino A De Angelis P | 2008 | Forest Ecology and Manage- ment2008，255，3： | 1 |
| 20 | Increased capillary endothelial cell protease adivity in response to angiogenic stimuli in vitro显示文摘 | Gross JL Moscatelli D Rifkin DB | 1983 | Proc Natl Acad Sci USA1983，80，9： | 1 |
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