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    题名 作者 年代 出处 被引量
1L^p-Boundedness of Marcinkiewicz Integrals with Hardy Space Function KernelsYong Ding Department of Mathematics, Beijing Normal University, Beijing 100875, P. R. China Dashan Fan Department of Mathematics, Anhui University and University of Wisconsin-Milwaukee. MW 53201 USA Yibiao Pan Department of Mathematics, University of Pittsburgh. Pittsburgh. Pennsylvania 15260. USA 2000Acta Mathematica Sinica,English Series2000,16,4:88
2Intra-habitat heterogeneity of microbial food web structure under the regime of eutrophication and sediment resuspension in the large subtropical shallow Lake Taihu, China显示文摘Wu QLL Chen YW Xu KD Liu ZW Hahn MW 2007中国生物学文摘2007,21,8:26
3格林-巴利综合征是中国急性软瘫的常见类型──北京郊区流行病学调查报告显示文摘采用病例监测方法,于1993年1月1日至12月31日在北京市平谷县和通县进行格林-巴利综合征(GBS)和急性软瘫(AFP)的流行病学调查。根据NINDS的标准,1993年该两县确诊为GBS者13例,年发病粗率1.3/10万人口,发病年龄专率高峰见于50 ̄59岁(3.6/10万)。7 ̄9月发病者占54%。全部患者临床和/或电生理表现均符合周围神经脱髓鞘为主的特点。AFP分类构成以GBS最多,占57%张振馨 Otte.,MW 1994中华神经精神科杂志1994,27,6:17
4Basic life support:knowledge and attitude of medical/paramedical professionals显示文摘BACKGROUND:Basic life support(BLS),a key component of the chain of survival decreases the arrest-cardiopulmonary resuscitation interval and increases the rate of hospital discharge.The study aimed to explore the knowledge of and attitude towards basic life support(BLS)among medical/paramedical professionals.METHODS:An observational study was conducted by assessing response to self prepared questionnaire consisting of the demographic information of the medical/paramedical staff,their personnel experience/attitude and knowledge of BLS based on the 2005 BLS Guidelines of European Resuscitation Council.RESULTS:After excluding incomplete questionnaires,the data from 121 responders(27 clinical faculty members,21 dental and basic sciences faculty members,29 house officers and 44 nurses and health assistants)were analyzed.Only 9(7.4%)of the 121 responders answered≥11,53(43%)answered 7-10,and 58(48%)answered<7 of 15 questions correctly.The clinical faculty members,house officers and nurses/HA had a mean score of 7.4±3.15,7.37±2.02 and 6.63±2.16 respectively,while dental/basic sciences faculty members attained a least mean score of 4.52±2.13(P<0.001).Those who had received cardiopulmonary resuscitation(CPR)training within 5 years obtained a highest mean score of 8.62±2.49,whereas those who had the training more than 5 years back or no training obtained a mean score of 5.54±2.38 and 6.1±2.29 respectively(P=0.001).Those who were involved in resuscitation frequently had a higher median score of 8 in comparison to those who were seldom involved or not involved at all(P<0.001).CONCLUSIONS:The average health personnel in our hospital lack adequate knowledge in CPR/BLS.Training and experience can enhance knowledge of CPR of these personnel.Thus standard of CPR/BLS training and assessment are recommended at our hospital.Shrestha Roshana Batajoo KH Piryani RM Sharma MW 2012World Journal of Emergency Medicine2012,3,2:11
5Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid Beta and impairment of learning and memory.显示文摘Zou LB Mouri A Iwata N Saido TC Wang D Wang MW Mizoguchi H Noda Y Nabeshima T 2006中国生物学文摘2006,20,9:10
6抗血管生成因子Angiostatin与Endostatin作用下肿瘤血管生成的二维数值模拟显示文摘目的数值模拟抗血管生成因子Angiostatin和Endostatin对肿瘤血管生成的影响。方法建立肿瘤内外血管生成的二维离散数学模型。模型耦合两种抗血管生成因子Angiostatin和Endostatin的抑制效应,数值模拟在促血管生成因子诱导下肿瘤微血管网生成,讨论血管生成抑制因子的影响。结果抗血管生成因子Angiostatin对肿瘤内外血管网络生成的速度和成熟度有抑制作用。抗血管生成因子Angiostatin和Endostatin耦合作用时,在肿瘤血管生成的早期有明显的抑制效应;在肿瘤血管生成的中后期,它们可以降低肿瘤血管化程度。结论本文模型能够较好的模拟抗血管生成因子Angiostatin和Endostatin对内皮细胞迁移和增殖的抑制作用。赵改平 高昊 吴洁 许世雄 Collins MW LONG Quan Carola Koenig Padhani AR 2006医用生物力学2006,21,4:10
7Repeated operations for infiltrative low - grade gliomas without intervening therapy.显示文摘OBJECT:Progression of infiltrative low-grade gliomas(LGGs)has been reported previously.The limitations ofsuch studies include diverse histological grading systems,intervening therapy,and the lack of histological confir-mation of malignant tumor progression.The aim of this study was to determine tumor progression in adult patientswith an initial diagnosis of infiltrative LGG who subsequently underwent a repeated operation,but no other inter-vening therapy.The authors examined factors that may be associated with tumor progression.Schmidt MH Berger MS Lamborn KR Aldape K McDermott MW Prados MD Chang SM 2003中国神经肿瘤杂志2003,1,2:8
8硬质合金和陶瓷的微波烧结显示文摘本文描述了有关碳化物强化氧化物陶瓷和硬质合金等粉末冶金产品的烧结热源即微波辐射的应用。除这些材料的微波烧结外,文中还列举了微波反应烧结实例。结果不仅表明了作为烧结工艺自身主要改进的微波烧结的潜能,而且还展示了提高传统硬质合金质量以及开发新型硬质材料,例如极精细显微结构材料的广阔前景。Pora.,MW 佘建芳 1997国外难熔金属与硬质材料1997,13,1:7
9Expression of co-stimulator 4-1BB molecule in hepatocellular carcinoma and adjacent non-tumor liver tissue,and its possible role in tumor immunity显示文摘AIM:To investigate the expression of 4-1BB molecule in hepatocellular carcinoma (HCC) and its adjacent tissues.METHODS:Reverse transcription-polymerase chain reaction (RT-PCR) was used to determine the gene expression of 4-1BB in hepatocarcinoma and its adjacent tissues,and peripheral blood mononuclear cells (PBMCs) from both HCC and health control groups.Flow cytometry was used to analyse the phenotypes of T cell subsets from the blood of HCC patients and healthy volunteers,and further to determine whether 4-1BB molecules were also expressed on the surface of CD4+ and CD8+ T cells. The localization of 4-1BB proteins on tumor infiltrating T cells was determined by direct immunofluorescence cytochemical staining and detected by confocal microscopy.RESULTS:4-1BB mRNA, which was not detectable in normal liver,was found in 19 liver tissues adjacent to tumor edge(<1.0cm).Low expression of 4-1BB mRNA was shown in 8 tumor tissues and 6 liver tissues located within 1 to 5cm away from tumor edge. In PBMCs, 4-1BB mRNA was almost not detected. Percentage of CD4^+, CD8^+ and CD3^+/CD25^+ T cells, as well as ratio of CD4 to CD8 revealed no difference between groups (P>0.05,respectively),while a significant lower percentage of CD3^+ T cell was found in HCC group as compared to healthy control group (P<0.05).However, 4-1BB molecules were almost not found on the surface of CD4+ and CD8+ T cells in HCC and healthy control group.Double-staining of 4-1BB^+/CD4^+ and 4-1BB^+/CD8^+ immunofluorescence on tumor infiltrating T cells was detected in 13 liver tissues adjacent to tumor edge (<1.0cm) by confocal microscopy.CONCLUSION: Although HCC may escape from immune attack by weak immunogenicity or downregulated expression of MHC-1 molecules on the tumor cell surface,tumor infiltrating T cells can be activated via other costimulatory signal pathways to exert a limited antitumor effect on local microenvironment. The present study also implicates that modulating 4-1BB/4-1BBL costimulatory pathway may be an effective immunotherapy strategy to augment the host response.Wan, YL Zheng, SS Zhao, ZC Li, MW Jia, CK Zhang, H 2004World Journal of Gastroenterology2004,10,2:6
10Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection显示文摘Fried MW Shiffman ML Reddy KR New England Journal of Medicine0,,:4
11肝脾猫抓病与腹痛显示文摘Dunn.,MW 徐德州 1997世界医学杂志1997,1,3:4
12Effect of IFNα-2a on Fas expression and apoptosis rate of peripheral blood cytotoxic T cells in patients with hepatitis B显示文摘Interferon(IFN) with antiviral and im-munomodulatory activities is one of the most important therapeutic agents for the treatment of chronic hepatitis. The apoptotic effect of IFN is influenced by cell type and the types of IFN, which suppresses proliferation and induces apoptosis in some cell types while inhibiting apoptosis in others. The aim of this study was to explore the effect of IFNα-2a on Fas expression and the apoptosis rate of peripheral blood cytotoxic T cells (CTLs) in patients with hepatitis B. METHODS:Peripheral blood mononuclear cells were isolated from 26 patients with hepatitis B including 16 patients with chronic hepatitis B and 10 patients with chronic severe hepatitis B. Fas expression and apoptosis rate of CTLs were analyzed with flow cytometry before and after IFNα-2a treatment. RESULTS:Before IFNα-2a treatment, Fas expression and apoptosis rate of CTLs from patients with chronic hepatitis B were significantly higher than those from patients with chronic severe hepatitis B and healthy controls respectively. No significant difference was observed between Fas expression and apoptosis rate of CTLs from patients with chronic severe hepatitis B and healthy controls. After IFNα-2a treatment,Fas expression and apoptosis rate of CTLs from different groups were compared with those before IFNα-2a treatment, showing no significant difference despite alternation of different degree. CONCLUSIONS:Activation induced cell death (AICD) exists in peripheral blood CTLs from patients with hepatitis B. No effect of IFNα-2a exerts on Fas expression and apoptosis rate of Fas in patients with hepatitis B.Institute of Infectious Diseases, Zhejiang University School of Medicine, Hangzhou 310003, China (Hou W, Liu KZ, Li MW and Wo JE) 2005Hepatobiliary & Pancreatic Diseases International2005,4,3:4
132004年4月1日磁通量传输事件特性的研究——通量管内电流密度、粒子运动与管轴方向的对比分析显示文摘本文利用Cluster四颗卫星上磁通门磁力计(FGM)的同时观测,采用旋度器方法(Curlometer),计算和分析了2004年4月1日12:24到12:54UT期间Cluster卫星观测的多个磁通量传输事件(FTEs)的特性。结果表明:磁通量管内电流密度较大,可达到约10-7A/m2。应用最小方向微分法(MDD),发现这些FTE事件具有准二维结构,即为圆柱形结构,其通量管轴线方向与管内电流方向及粒子运动方向基本平行。张清和 刘瑞源 黄际英 Dunlop MW 胡红桥 沈超 Bogdanova YV 2007极地研究2007,19,2:3
14实体肿瘤血管任意方向生成的二维数值模拟显示文摘目的二维数值生成实体肿瘤任意方向生长的血管网,为研究实体肿瘤内血液动力学、药物输运以及抗血管生成提供更趋真实的微血管网络结构。方法将新生血管芽尖的内皮细胞迁移方向由先前模型的上、下、左、右四个方向扩展为任意方向,建立相应的二维离散模型,数值模拟实体肿瘤微脉管系统的生成过程,比较模拟结果与相关实验数据的符合程度。结果对盲肠肿瘤微血管网进行数值模拟,与改进前的模型和其他模型比较,本模型生成的肿瘤微血管网结构特征,如血管的走向、扭曲、分叉与融合等,更接近生理实际,与实验观测图像的相似度更高。结论该模型可模拟实体肿瘤的微血管网生成,为肿瘤内血液微循环、药物传递以及抗血管生成的理论研究提供较为接近实际的微血管网络结构。吴洁 许世雄 龙泉 Collins MW Carola Koenig 赵改平 蒋雨平 Padhani AR 2007医用生物力学2007,22,1:2
15头颈癌,鼻咽癌,肺癌和结肠癌中的循环免疫球蛋白A免疫复合物(英文)显示文摘A double antibody enzyme-linked immunosorbent assay (ELISA) was developed to quantitate circulating immune complexed IgA (IgA IC) in human serum. The serum panel for this study consisted of normal blood donors, benign surgery (BS), head and neck cancer (HN),Baseler MW 1987肿瘤防治研究1987,15,4:2
16Relationship between visual evoked potentials and intracranial pressure显示文摘York DH Pulliam MW Rosenfeld JG 1981J Neurosurg1981,55,:2
17Bortezomib or high-dose dexamethasone for relapsed multiple myeloma显示文摘Richardson PG Sonneveld P Schuster MW 0,,:2
18Mandarin and English single word processing studied with functional magnetic resonance imaging显示文摘Chee MW Tan EW Thiel T 1999J Neurosci1999,19,:2
19Homology and heterology between the secreted antigens of the parasitic larval stages of Ascaris lumbricoides and Ascaris suum显示文摘Kennedy MW Qureshe J Haswell-Elkins M 1987Clin Exp Immunol1987,67,:2
20The nematode polyprotein allergens/antigens 显示文摘Kennedy MW 2000Parasitol Today2000,16,:2
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