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| 1 | 高危患者目标血压与心血管病预后显示文摘指南推荐血压目标值应〈140/90 mmHg(1mmHg=0.133kPa)以减少心血管事件的发生。但与其他心血管病预后(如冠状动脉事件)相比,包括脑卒中及心力衰竭在内的心血管病预后与收缩压下降关系更密切。一些心血管事件(如冠状动脉事件)风险在收缩压低时亦增高,风险-收缩压关系呈J形曲线,而脑卒中与血压不是J形曲线关系。 | B?hm M Schumacher H Teo KK Lonn EM Mahfoud F Mann JF Mancia G Redon J Schmieder RE Sliwa K Weber MA Williams BYusuf S 曲浥晨 叶鹏 | 2017 | 中华高血压杂志2017，25，6： | 14 |
| 2 | 阿尔茨海默病患者的脑淀粉样血管病变显示文摘 | 田金洲 时晶 程龙 David M A Mann | 2003 | 中华老年医学杂志2003，22，11： | 6 |
| 3 | 子宫内膜切除术治疗月经过多显示文摘月经过多是指在一次月经周期中,行经期长于7天或出血量大于80mL的状态.世界卫生组织调查14个国家的5 322例女性,发现1 011例患月经过多,占调查人数的19%[1],其中功能性子宫出血占60%.月经过多(特别是功能性子宫出血)常用的治疗方法包括药物治疗、清宫术、子宫切除术及近年来开展的子宫内膜切除术[2,3]. | 余艳红 全松 Mann M Yang | 2002 | 中国实用妇科与产科杂志2002，18，8： | 5 |
| 4 | A next-generation marker genotyping platform(AmpSeq)in heterozygous crops:a case study for marker-assisted selection in grapevine显示文摘Marker-assisted selection(MAS)is often employed in crop breeding programs to accelerate and enhance cultivar development,via selection during the juvenile phase and parental selection prior to crossing.Next-generation sequencing and its derivative technologies have been used for genome-wide molecular marker discovery.To bridge the gap between marker development and MAS implementation,this study developed a novel practical strategy with a semi-automated pipeline that incorporates trait-associated single nucleotide polymorphism marker discovery,low-cost genotyping through amplicon sequencing(AmpSeq)and decision making.The results document the development of a MAS package derived from genotyping-by-sequencing using three traits(flower sex,disease resistance and acylated anthocyanins)in grapevine breeding.The vast majority of sequence reads(⩾99%)were from the targeted regions.Across 380 individuals and up to 31 amplicons sequenced in each lane of MiSeq data,most amplicons(83 to 87%)had<10%missing data,and read depth had a median of 220–244×.Several strengths of the AmpSeq platform that make this approach of broad interest in diverse crop species include accuracy,flexibility,speed,high-throughput,low-cost and easily automated analysis. | Shanshan Yang Jonathan Fresnedo-Ramíre Minghui Wang Linda Cote Peter Schweitzer Paola Barba Elizabeth M Takacs Matthew Clark James Luby David C Manns Gavin Sacks Anna Katharine Mansfield Jason Londo Anne Fennell David Gadoury Bruce Reisch Lance Cadle-Davidson Qi Sun | 2016 | Horticulture Research2016，3，1： | 2 |
| 5 | The oxidation of iron-chromium alloys in ferrous chloride solution at 300℃显示文摘 | Mann M W Teare P W | 1972 | Corrosion Science1972，，12： | 2 |
| 6 | Use of nerve blocks for botulinum toxin treatment of palmar-plantar hyperhidrosis显示文摘 | Fujita M Mann T Mann O | 2001 | J Am Acad Dermatol2001，45，： | 2 |
| 7 | Protein interaction screening by quantitative immunoprecipitation combined with knockdown (QUICK)显示文摘 | Selbach M Mann M | 2006 | Nat Methods2006，3，12： | 1 |
| 8 | Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha synuelein: Implication for alpha-synueleinopathies显示文摘 | ISHII A NONAKA T TANIGUCHI S SAOTO T ARAI T MANN D IWATSUBO T HISANAQA S GOEDERT M HASEQAWA M | 2007 | FEBS Lett2007，581，24： | 1 |
| 9 | Mapping of phosphorylation site of gel-isolated proteins by nanoelectrospray tandem mass spectrometry: potentials and limitations显示文摘 | Mann M | 1999 | Anal Chem1999，71，： | 1 |
| 10 | Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implica tions for cell based vascular therapy显示文摘 | Griese D P Ehsan A Melo L G Kong D Zhang L Mann M J | 2003 | Circulation2003，108，： | 1 |
| 11 | Observed and simulated muhidecadal variability in the Northern Hemisphere显示文摘 | DELWORTH T L MANN M E | 2000 | Climate Dynamics2000，16，9： | 1 |
| 12 | Antimony tri- oxide-induced apoptosis is dependent on SEKI/JNK sig- naling 显示文摘 | MANN K K DAVISON K COLOMBO M | 2006 | Toxicology letters2006，160，1： | 1 |
| 13 | Axin-mediated CKI phosphorylation of beta -catenin at Set 45:a molecular switch for the Wnt pathway显示文摘 | Amit S Hatzubai A Birman Y Andersen J S Ben Shushan E Mann M | 2002 | Genes Dev2002，16，： | 1 |
| 14 | Activation of the unfolded protein response is necessary and sufficient for reducing topoisomersse IIalpha protein levels and decreasing sensitivity to topoisomerase-targeted drugs显示文摘 | Gray MD Mann M Nitiss JL | 2005 | Mol Pharmacol2005，68，： | 1 |
| 15 | Cerebral amyloid angiopathy and de- mentia显示文摘 | Tian J Shi J Mann D M | 2004 | Panminerva Med2004，46，： | 1 |
| 16 | The Toxicity of Glyphosate and Several Glyphosate Formuahions to Four Species of Southwestern Australian Frogs显示文摘 | Mann R M Bidwell J R | 1999 | Archives of environmental contamination and toxicology1999，36，2： | 1 |
| 17 | Purification and characterization of perlucin and perlustrin, two new proteins from the shell of the mollusc Haliotis laevigata显示文摘 | Weiss I M Kaufmann S Mann K | 2000 | Biochem Biophys Res Commun2000，267，： | 1 |
| 18 | Differential effects of culture on imprinted H19 expression in the preimplantation mouse embryo 显示文摘 | DOHERTY A S MANN M R TREMBLAY K D | 2000 | Biology of Reproduction2000，62，： | 1 |
| 19 | Immunohistochemically detected micrometastases of the lymph modes in patients with gastric carcinoma显示文摘 | Fukagawa T Sasako M Mann GB | 2003 | Cancer 20032003，92，4： | 1 |
| 20 | Climate over past millennia 显示文摘 | Jones P D Mann M E | 2004 | Rev Geophys2004，42，2002： | 1 |
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