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| 1 | 异型缝隙连接通道和磷酸化对心脏缝隙连接的调变显示文摘目的 检测由缝隙连接蛋白 (connexin ,Cx) 4 3和Cx4 5组成的多种异型缝隙连接通道 (het eromultimericgapjunctionchannels ,HGJC)和磷酸化对缝隙连接 (gapjunction ,GJ)的调变作用。方法 将转染了编码为Cx4 3或Cx4 5的DNA后的Hela细胞放置在一起共同培养组成双侧和单侧异型GJ通道。显微注射若丹明 12 3(rhodamine 12 3,Rh)检测经 2 0 0nmol/L十四 (烷 )酰佛波醇乙酸酯 (12 0 tetrade canoylphorbol 13 acetae ,TPA)处理前后 ,在紫外光显示下由Cx4 3和Cx4 5所组成的不同GJ通道对荧光染料的偶联率 (couplingratio)。结果 在不同的GJ中 ,同型GJ通道Cx4 3(homotypicCx4 3,HoCx4 3)偶联率最高。从Cx4 5侧注入荧光染料的单侧异型GJ通道 4 5 (mono heteromericCx4 5 Cx4 3/4 5 ,MH4 5 )偶联率较之从Cx4 3/4 5侧注入荧光染料的MH4 5、双侧异型GJ通道Cx4 3/4 5 (bi heteromericCx4 3/4 5 ,BH4 3/4 5 )及同型GJ通道Cx4 5 (homotypicCx4 5 ,HoCx4 5 )等的偶联率是最低的。根据HoCx4 3或HoCx4 5通道的偶联率对各型通道偶联率进行标准化处理。BH4 3/4 5和MH4 3通道的偶联率均较HoCx4 3降低。对MH4 5通道来说 ,从Cx4 3/4 5侧注射的通道偶联率大于从Cx4 5侧注射的偶联率。TPA处理后HoCx4 3的偶联率降低 。 | 钟国强 黄从新 刘唐威 Mantel PL Moreno AP | 2003 | 中华心律失常学杂志2003，7，4： | 9 |
| 2 | AIDS-Related Knowledge, Attitudes and Behavior Survey among the “Migrant” Population in China显示文摘Objective To realize AIDS related knowledge, attitude and behavior among floating people in China and discuss its influencial factors, and to provide the evidence for how to prevent AIDS in floating population. Methods The data were collected from the “Sex and Reproductive Health Baseline Survey among Floating People in China” conducted in March 2004. The standard questionnaires were used to interview altogether 4 900 floating people from 6 provinces. Results Nearly 95.4 % of them had heard about AIDS, but only 0.5% can judge all the transmitted ways and no-transmitted ways correctly, 45.9 % believed that we need to isolate the HIV positive people. Only 65.7% knew that using condom can preventive HIV infection, 43.7% showed their understanding about the man who has long time no sexual life has sex with a sexual worker. About 13.6% floating people chose condom as FP method and among them only 34.6% used condom every time. Conclusion Chinese floating people are lack of AIDS knowledge. Most of them do not practise Safe Sex Activity. We need to give more intervention to the floating population. | Jian-fang ZHOU Xiao-ming SUN Jonanne Mantell Xiao-mei RU Yong WEN | 2007 | Journal of Reproduction and Contraception2007，18，2： | 5 |
| 3 | 异型缝隙连接通道和磷酸化对心脏细胞通讯的调节作用显示文摘为了检测缝隙连接蛋白 (Cx) 4 3和Cx4 5组成的多种异型缝隙连接通道和磷酸化对缝隙连接 (GJ)里细胞通讯的调节作用 ,将转染了编码为Cx4 3或Cx4 5的DNA后的Hela细胞放置在一起共同培养组成双侧和单侧异型GJ通道。显微注射荧光素黄 (LY)后 ,利用紫外光检测经 2 0 0nmol/L十四 (烷 )酰佛波醇乙酸酯 (TPA)处理前后由Cx4 3和Cx4 5所组成的多种异型GJ通道对荧光染料的偶联率。结果 :在不同的GJ中 ,同型GJ通道Cx4 3(HoCx4 3)偶联率最高。单侧异型GJ通道Cx4 3(MH4 3)和单侧异型GJ通道Cx4 5 (MH4 5 )的偶联率较之相关的HoCx4 3和同型GJ通道Cx4 5 (HoCx4 5 )低。从Cx4 5侧注入荧光染料的MH4 5偶联率较之从Cx4 3/ 4 5侧注射的MH4 5、双侧异型GJ通道Cx4 3/4 5 (BH4 3/ 4 5 )和HoCx4 5等的偶联率都低。TPA处理后HOCx4 3的偶联率降低 ,而当Cx4 3和Cx4 5组合成异型BH4 3/4 5和MH4 3通道其偶联率下降更显著。结论 :Cx4 3和Cx4 5共同表达可构成BH4 3/ 4 5、MH4 3和MH4 5等通道 ,而这些异型GJ通道可降低细胞间通信和对磷酸化的敏感性。有关MH4 5通道 ,其偶联率大小决定于荧光染料的注射方向 ,此可能与心律失常再折返的解剖学的机制有关。 | 钟国强 黄从新 刘唐威 Patricia Lynn Mantel Alonso P.Moreno | 2003 | 中国心脏起搏与心电生理杂志2003，17，3： | 4 |
| 4 | Reproductive and Sexual Health of Chinese Migrants显示文摘Objective To investigate the reproductive and sexual health situation,including knowledge,attitudes,and behaviors,among a population-based sample of internal migrant workers in China.Methods A cross-sectional survey of 4 900 rural-to-urban migrants in 6 provinces of China was conducted.Participants completed a 30-min semi-structured questionnaire about contraceptive practices,sexual behavior,and HIV-related knowledge.Results Migrants lacked knowledge of reproductive and sexual health issues.Among those who had heard any sexually transmitted infections(STIs),only 79.1%,46.2%,86.1%,14.5% and 82.2%,respectively,knew that gonorrhea,condyloma,syphilis,chancroid,and AIDS were STIs.About three-quarters of participants had not used any contraceptive method at sexual debut.Among current users of contraceptive methods,85.5% indicated that they were satisfied with the method.Before adoption of a contraceptive method,46.6% of the migrant workers were unaware of the advantages/disadvantages of the method and 75.3% had no knowledge of emergency contraception.Nearly one-quarter(23.4%) reported that they had premarital sex.Among migrants who were sexually active one month prior to the survey,only 14.0% reported that they had used condoms.Conclusion The limited sexual and reproductive health knowledge and unmet reproductive health services of migrant workers in China underscore the need for a comprehensive package of sexual and reproductive health interventions that combine cognitive and behavioral skills training and target both migrants and health care providers. | Jian-fang ZHOU Joanna E Mantell Xiao-mei RU | 2009 | Journal of Reproduction and Contraception2009，20，3： | 2 |
| 5 | Correlation between severity of thyroid dysfunction and renal function显示文摘 | den HOLLANDER JG WULKAN RW MANTEL MJ | 2005 | Clin Endocrinol(Oxf)2005，62，4： | 1 |
| 6 | Order oriented slotting: a new assignment strategy for warehouses 显示文摘 | Mantel R J Schuur P C | 2007 | European Journal of Industrial Engineering2007，1，3： | 1 |
| 7 | The detection of disease clustering and a generalized regression approach显示文摘 | Mantel NA | 1967 | Cancer Res1967，27，： | 1 |
| 8 | Severe acute maternal morbidity: a pilot study of a definition for a near-miss 显示文摘 | Mantel GD Buchmamm E Rees H | 1998 | BJOG1998，105，： | 1 |
| 9 | Molecular mechanisms underlying FOXP3 induction in human T cells显示文摘 | Mantel PY Ouaked N Rttckert B | 2006 | J Immunol2006，176，6： | 1 |
| 10 | The detection of disease clustering and a generalized regression approach 显示文摘 | Mantel N | 1967 | Cancer Research1967，27，： | 1 |
| 11 | Is Cystatin C a Marker of Glomerular Filtration Rate in Thyroid Dysfunction? 显示文摘 | den Hollander J G Wulkan R W Mantel M J | 2003 | Clinical Chemistry2003，49，9： | 1 |
| 12 | Statistical aspects of the analysis of data from retrospective studies of disease显示文摘 | Mantel N Haenszel W | 1959 | J Natl Cancer Inst1959，22，4： | 1 |
| 13 | Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability 显示文摘 | Mantel C Guo Y Lee MR | 2007 | Blood2007，109，10： | 1 |
| 14 | Thyroidautoimmunity and abortion; a prospective study in womenundergoing in vitro fertilization 显示文摘 | Muller AF Verhoeff A Mantel MJ | 1999 | Fertil Steril1999，71，： | 1 |
| 15 | Sirtuin 1, stem cells, aging, and stem cell aging 显示文摘 | Mantel C Broxmeyer HE | 2008 | Current opinion in hematology2008，15，4： | 1 |
| 16 | Intravitreal ranibizumab (Lucentis) for the treatment of myopic ehoroidal neovascularization显示文摘 | Konstantinidis L Mantel I Poumaras JA | 2009 | Graefes Arch Clin Exp Ophthalmol2009，247，3： | 1 |
| 17 | Foliar and yield response of Santa Rosa plum to saline water spray显示文摘 | Mantell A Mead R M Hoffman G J | 1989 | Irrigation Science1989，10，1： | 1 |
| 18 | The acceptabillty of the female condom: perspectives of family planning providers in New York City ,South Africa,and Nigeria 显示文摘 | Mantell J E Hoffman S Weiss E | 2001 | J Urban Health2001，78，4： | 1 |
| 19 | The detection of disease clustering and a generalized regression approach 显示文摘 | Mantel N | 1967 | Cancer Res1967，27，： | 1 |
| 20 | Statistical aspects of the analysis of data from retrospective studies 显示文摘 | Mantel N Haenszel W | 1959 | J Natl Cancer Inst1959，22，4： | 1 |
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