|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 3 | Phthalates determination in pharmaceutical formulae used in parenteral nutrition by LC-ES-MS: Importance in public health 显示文摘 | Cristina P F Maria C B A Antia S D | 2010 | Analytical and Bioanalytieal Chemistry2010，397，2： | 1 |
| 4 | Effects of foliar sprayscontaining calcium, magnesium and titanium on plum (Prunus domestica L) fruit quality 显示文摘 | Carlos A L Maria B Carlos F A | 2003 | Journal of Plant Physiology2003，160，12： | 1 |
| 5 | Recurrent Pain in Children and Adolescents显示文摘 | Ana Maria B | 2003 | Jornal de Pediatria2003，79，1： | 1 |
| 6 | Tennis players show a lowercoactivation of the elbow antagonist muscles during isokineticexercises 显示文摘 | Ilenia B Maria ER Francesco F | 2008 | J Electromyogra Kinesiol2008，18，： | 1 |
| 7 | Postharvest treatment with(-)and(+)methyl jasmonate stimulates anthocyanin accumulation in grapes显示文摘 | GEMA F GRACIA P B MARIA L R | 2015 | LWT-Food Science and Technology2015，62，1： | 1 |
| 8 | Cholesterol photosensitised oxidation of horse meat slices stored under different packaging films显示文摘 | Emanuele B Maria TR Federico F | 2010 | Meat Science2010，85，： | 1 |
| 9 | Effects offchilling to 0 ℃ on the morphology of meiotic spindles in human metaphase Ⅱ oocytes显示文摘 | Maria TZ Ryszard B Robert F | 2001 | Fertil Steril2001，75，4： | 1 |
| 10 | Parameters affecting microwave-assisted extraction of organophosphorus pesticides from agricultural soil显示文摘 | EDWAR F MARiA E B RONNIE L | 2007 | Journal of Chromatography A2007，1169，12： | 1 |
| 11 | A high-frequency (95 GHz) electron paramagnctic resonance study of B-doped Ti02 photocatalysts显示文摘 | MARIA F A VALENTINA G B TIZIANO M B PAOLO F | 2008 | Inorganica Chimica Acta2008，361，： | 1 |
| 12 | Refinement of the 12q14 microdeletion syndrome: primordial dwarfism and developmental delay with or without ostenpoikilosis 显示文摘 | Marl F Hermanns P Maria L Galluzzi F Scott D Lee B | 2009 | EuropJHumanGenet2009，17，10： | 1 |
| 13 | Pro up regulation: a diagn illicit use of oestrog ens in adult beef cattle显示文摘 | Divari S Mulasso C Spada F De Maria R gesterone receptor ostic tool for the Uslenghi F Cannizzo FT Brina N Biolatti B | 2011 | Tumour Biol2011，28，12： | 1 |
| 14 | The problem of assigning responsibility for greenhouse gas emissions 显示文摘 | Simone B Maria P F Enzo T | 2004 | Ecological Economics2004，，49： | 1 |
| 15 | Synthesis of Ziegler-Natta Catalysts for replication during Propylene Polymerization显示文摘 | Coutinho F M B Costa M A S Santa Maria L C | 1992 | Polym Bull1992，，28： | 1 |
| 16 | The fuzzy Kalman filter: State estimation using possibilistic techniques 显示文摘 | Maria F Jimenez A AI Hadithi B M | 2006 | Fuzzy Sets and Systems2006，157，16： | 1 |
| 17 | Effectiveness of Mindful ness-Based Cognitive Therapy on the Quality of Life, Emotional Status,and CD4 Cell Count of Patients Aging with HIV Infection 显示文摘 | Marian G G Maria J F Xavier B | 2014 | AIDS Behav2014，18，4： | 1 |
| 18 | Seasonal and tidal influence on the variability of nitrous oxide in the Tagus estuary 显示文摘 | CELIA G MARIA J B MARIA F C | 2010 | Portugal Scientia Marina2010，74，1： | 1 |
| 19 | Analytical study ofthe pyrolysis process in a wastewater treatment pilotstation显示文摘 | Khiari B Marias F Zagrouba F | 2004 | Desalination2004，167，： | 1 |
| 20 | Influence of mortar rheology on aggregates settlement 显示文摘 | PETROU M F WAN B GADALA - MARIA F | 2000 | ACI Materials Journal2000，97，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员