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| 1 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice显示文摘AIM: To study isolation and chemical characterization of pectin derived from the common cranberry Vaccinium oxycoccos L. (oxycoccusan OP) and the testing of its preventive effect on experimental colitis.METHODS: Mice were administrated orally with OP two days prior to a rectal injection of 5% acetic acid and examined for colonic damage 24 h later. Colonic inflammation was characterized by macroscopical injury and enhanced levels of myeloperoxidase activity measured spectrophotometrically with o-phenylene diamine as the substrate. The mucus contents of the colon were determined by the Alcian blue dye binding method. Vascular permeability was estimated using 4% Evans blue passage after i.p. injection of 0.05 mol/L acetic acid. RESULTS: In the mice treated with OP, colonic macroscopic scores (1.1 ± 0.4 vs 2.7, P < 0.01) and the total square area of damage (10 ± 2 vs 21 ± 7, P < 0.01) were significantly reduced when compared with the vehicle-treated colitis group. OP was shown to decrease the tissue myeloperoxidase activity in colons (42 ± 11 vs 112 ± 40, P < 0.01) and enhance the amount of mucus of colitis mice (0.9 ± 0.1 vs 0.4 ± 0.1, P < 0.01). The level of colonic malondialdehyde was noted to decrease in OP-pretreated mice (3.6 ± 0.7 vs 5.1 ± 0.8, P < 0.01). OP was found to decrease the inflammatory status of mice as was determined by reduction of vascular permeability (161 ± 34 vs 241 ± 21, P < 0.01). Adhesionof peritoneal neutrophils and macrophages was also shown to decrease after administration of OP (141 ± 50 vs 235 ± 37, P < 0.05).CONCLUSION: Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected. A reduction of neutrophil infiltration and antioxidant action may be implicated in the protective effect of oxycoccusan. | Sergey V Popov Pavel A Markov Ida R Nikitina Sergey Petrishev Vasily Smirnov Yury S Ovodov | 2006 | World Journal of Gastroenterology2006,12,41: | 9 |
| 2 | 现有防疫通风措施及基于先进气流组织的源头控制技术应用显示文摘新冠疫情暴发后,如何应对呼吸道传染病的传播这一难题再次摆在了人们面前.通风是最重要的工程防疫措施,ASHRAE、REHVA、SHASE以及中国的相关机构、学会就如何利用暖通空调系统有效防控COVID-19的传播相继出台了指导性文件.总结和分析系列指导性文件中有关通风量和气流组织方面的内容,发现现有工程防疫措施尚存在诸多需改进之处.传统的全空间通风在疫情期间表现出通风量不足、对近距离短期暴露事件效率低下、能耗高等缺陷,而基于先进气流组织的源头控制技术具有控制效率高、个性化可调、响应快速且节能潜力大等优势,恰好可弥补全空间通风的不足.在此基础上,系统地总结了基于先进气流组织的源头控制措施在呼吸道传染病传播控制方面的技术类型,并考虑到后疫情时代通风系统设计面临以“平疫结合”为导向的发展趋势,探讨了在“平疫结合”中应用源头控制技术的优势,以及在一些高风险场景应用源头控制从而实现“平疫结合”的技术路线,并分析了为落实“平疫结合”设计理念所需进一步探索的技术方向.所做探索预期为后续指南的编撰提供参考,为未来防疫通风设计带来新思路和新启示. | 艾正涛 叶金军 MELIKOV A K MARKOV D G | 2022 | 湖南大学学报(自然科学版)2022,49,5: | 6 |
| 3 | Sur une question posée par D I Mendeleieff显示文摘 | | | J Izv Acad Nauk St Petersburg0,62,: | 1 |
| 4 | The treatment of the rubeosis of the iris and the neovascular glaucoma in proliferative diabetic retinopathy by means of anti - VEGF 显示文摘 | Cemak M Markovic O Cemak A | 2008 | Cesk Slov Oftalmol2008,64,6: | 1 |
| 5 | Oxygen reduction reaction on Pt (111): effects of bromide 显示文摘 | Markovic N M Gasteiger H A Grgur B N | 1999 | J Electroanal Chem1999,467,: | 1 |
| 6 | Pituitary adenylate cyclase-acti- vating polypeptide plays a key role in nitroglycerol-induced trigeminovascular activation in mice 显示文摘 | Markovics A Kormos V Gaszner B | 2012 | Neurobiology of Disease2012,45,: | 1 |
| 7 | Prognosis of dislocation after total hip arthroplasty显示文摘 | Lee CM Markovic I | 1998 | J Arthroplasty1998,13,: | 1 |
| 8 | Massive sul- fide deposits discovered at 14°45rN, Mid-Atlantic Ridge显示文摘 | Batuev B N Krotov A G Markov V F | 1994 | British Ridge Newsletter1994,6,: | 1 |
| 9 | Myeoplas- ma contamination of cell cultures: interference with 32p-la- belling pattern of RNA显示文摘 | Markov GG Bradvarova I Mintcheva A | 1969 | Exp Cell Res1969,57,23: | 1 |
| 10 | Synthesis of reversible logic circuits 显示文摘 | Shende V V Prasad A K Markov I L | 2003 | IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems2003,22,6: | 1 |
| 11 | Segmental expression of claudin proteins correlates with fight junction barrier properties in rat intestine显示文摘 | Markov AG Veshnyakova A Fromm M | 2010 | J Comp Physiol B2010,180,4: | 1 |
| 12 | Methanol electrooxidation on well-characterized platinum-ruthenium bulk alloys 显示文摘 | GASTEIGER H A MARKOVIC N ROSS Jr P N | 1993 | The Journal of Physical Chemistry1993,97,12: | 1 |
| 13 | Production of nitride and carbonitride powders from inorganic azides by self-propagating high-temperature synthesis显示文摘 | Amosov A P Bichurov G V Markov Y M | 1997 | Refractories and Industrial Ceramics1997,38,11: | 1 |
| 14 | Pronounced association of elevatedserumhomocysteinewithstrokeinsubgroupsofindividuals:a nationwidestudy显示文摘 | Towfighi A Markovic D Ovbiagele B | | Journal of Neuroscience0,,: | 1 |
| 15 | Balloon dilatation and in- sertion of temporary coated stents using a retrograde approach in pa- tients with irreversible strictures of the distal ureter显示文摘 | Zeljko M Markovic B Mladenovic A | 2010 | Jpn J Radi- ol2010,28,9: | 1 |
| 16 | Pronounced association of elevated serum homocysteine with stroke in subgroups individuals:a nationwide study显示文摘 | I Towfighi A Markovic D Ovbiagele B | 2010 | J Neurol Scl2010,298,: | 1 |
| 17 | Risk factors and dis- tribution of symptomatic venous thromboembolism in total hip and knee replacements : prospective study 显示文摘 | Markovic -Denic L Zivkovic K Lesic A | 2012 | Int Orthop2012,36,6: | 1 |
| 18 | Massive sulfide deposits discovered at 14° 45' N, Mid Atlantic Ridge 显示文摘 | Batuev B N Krotov A G Markov V F | 1994 | British Ridge Newsletter1994,6,: | 1 |
| 19 | Sur Quelques cas des Théorèmes sur les Limites de Probabilité et des Espérances Mathématiques显示文摘 | Markov A A | | 0,,: | 1 |
| 20 | On the reaction pathway for methanol and carbon monoxide electrooxidation on Pt-Sn alloy versus Pt-Ru alloy surfaces显示文摘 | Wang K Gasteiger H A Markovic N M | 1996 | Electrochimica Acta1996,41,16: | 1 |