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| 1 | Review of the diagnosis and management of gastrointestinal bezoars显示文摘The formation of a bezoar is a relatively infrequentdisorder that affects the gastrointestinal system.Bezoars are mainly classified into four types dependingon the material constituting the indigestible mass of thebezoar phytobezoars, trichobezoars, pharmacobezoars,and lactobezoars. Gastric bezoars often cause ulcerativelesions in the stomach and subsequent bleeding,whereas small intestinal bezoars present with smallbowel obstruction and ileus. A number of articles haveemphasized the usefulness of Coca-Cola? administrationfor the dissolution of phytobezoars. However, persimmonphytobezoars may be resistant to such dissolutiontreatment because of their harder consistency comparedto other types of phytobezoars. Better understanding ofthe etiology and epidemiology of each type of bezoarwill facilitate prompt diagnosis and management.Here we provide an overview of the prevalence, classification,predisposing factors, and manifestations ofbezoars. Diagnosis and management strategies arealso discussed, reviewing mainly our own case series.Recent progress in basic research regarding persimmonphytobezoars is also briefly reviewed. | Masaya Iwamuro Hiroyuki Okada Kazuhiro Matsueda Tomoki Inaba Chiaki Kusumoto Atsushi Imagawa Kazuhide Yamamoto | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，4： | 22 |
| 2 | Immunotherapy in gastric cancer显示文摘Gastric cancer is the second most common of cancerrelated deaths worldwide.In the majority of cases gastric cancer is advanced at diagnosis and although medical and surgical treatments have improved,survival rates remain poor.Cancer immunotherapy has emerged as a powerful and promising clinical approach for treatment of cancer and has shown major success in breast cancer,prostate cancer and melanoma.Here,we provide an overview of concepts of modern cancer immunotherapy including the theory,current approaches,remaining hurdles to be overcome,and the future prospect of cancer immunotherapy in the treatment of gastric cancer.Adaptive cell therapies,cancer vaccines,gene therapies,monoclonal antibody therapies have all been used with some initial successes in gastric cancer.However,to date the results in gastric cancer have been disappointing as current approaches often do not stimulate immunity efficiently allowing tumors continue to grow despite the presence of a measurable immune response.Here,we discuss the identification of targets for immunotherapy and the role of biomarkers in prospectively identifying appropriate subjects or immunotherapy.We also discuss the molecular mechanisms by which tumor cells escape host immunosurveillance and produce an immunosuppressive tumor microenvironment.We show how advances have provided tools for overcoming the mechanisms of immunosuppression including the use of monoclonal antibodies to block negative regulators normally expressed on the surface of T cells which limit activation and proliferation of cytotoxic T cells.Immunotherapy has greatly improved and is becoming an important factor in such fields as medical care and welfare for human being.Progress has been rapid ensuring that the future of immunotherapy for gastric cancer is bright. | Satoko Matsueda David Y Graham | 2014 | World Journal of Gastroenterology2014，20，7： | 19 |
| 3 | A large impact of tropical biomass burning on CO and CO_2 in the upper troposphere显示文摘A large interannual variation of biomass burning emissions from Southeast Asia is associated with the ENSO events. During 1997/98 and 1994 El Nino years, uncontrolled wildfires of tropical rainforests and peat lands in Indonesia were enlarged due to a long drought. Enhanced CO injection into the upper troposphere from the intense Indonesian fires was clearly observed in the 8-year measurements from a regular flask sampling over the western Pacific using a JAL airliner between Australia and Japan. This airliner observation also revealed that upper tropospheric CO2 cycle largely changed during the 1997 El Nino year due partly to the biomass burning emissions. Widespread pollution from the biomass burnings in Southeast Asia was simulated using a CO tracer driven by a 3D global chemical transport model. This simulation indicates that tropical deep convections connected to rapid advection by the subtropical jet play a significant role in dispersing biomass-burning emissions from Southeast Asia on a global scale. | Hidekazu Matsueda Shoichi Taguchi Hisayuki Y. Inoue Masao Ishii | 2002 | Science China(Life Sciences)2002，45，z1： | 2 |
| 4 | An efficient method for the preparation of ω,ω'-bis-urethane protected arginine derivatives, synthesis commun显示文摘 | Wu Y Matsueda G R Bematowicz M S | 1993 | 23 (21): 3 055- 3 0601993，23，21： | 1 |
| 5 | Measurements of atmospheric CO2from a meteorological tower in Tsukuba, Japan 显示文摘 | Inoue H Y Matsueda H | 2001 | Tellus B2001，53，3： | 1 |
| 6 | Intractable massive ascites following radical gastroectomy, treatment with local intraperi tonealadministration of OK - 432 using a unified CT and fluoroscopy system显示文摘 | Inaba Y Arai Y Matsueda K | 2003 | Australas Radiol2003，47，4： | 1 |
| 7 | Antitumor-active photochemical oxidation products of provitamin D显示文摘 | MATSUEDA S KATSUKURA Y | 1985 | Chemistry & industry1985，1，： | 1 |
| 8 | Patients with constipation-predominant irritable bowel syndrome (IBS) may have elevated serotonin concentrations in colonic mucosa as compared with diarrheapredominant patients and subjects with normal bowel habits 显示文摘 | MIWA J ECHIZEN H MATSUEDA K | 2001 | Digestion2001，63，： | 1 |
| 9 | A new epitope peptide derived from hepatitis C virus 1 b possessing the capacity to induce cytotoxic T-lymphoeytes in HCV1b-infected patients with HLA-A11, -A31, and -A33 显示文摘 | Matsueda S Yamada A Takao Y | 2007 | Cancer Immunol Immunother2007，56，9： | 1 |
| 10 | Hepatoid carcinoma of the pancreas producing protein induced by vitamin K absence or antagonist Ⅱ (PIVKA-Ⅱ) and alpha- fetoprotein (AFP)显示文摘 | Matsueda K Yamamoto H Yoshida Y | 2006 | J Gastroenterol2006，41，10： | 1 |
| 11 | Innovative appoaches to plasminogen activator therapy 显示文摘 | Haber E Quertermous T Matsueda G R | 1989 | Science1989，243，4887： | 1 |
| 12 | Breast cancer cells ex-pressing stem cell markers CD44+CD24lo are eliminatedby Numb-1 peptide-activated T cells显示文摘 | Mine T Matsueda S Li Y | 2009 | Cancer Immu-nol Immunother2009，58，8： | 1 |
| 13 | Personalized peptide vaccination for advanced biliary tract cancer: IL-6, nutritional status and pre-existing antigen-specific immunity as possible biomarkers for patient prognosis 显示文摘 | Yoshitomi M Yutani S Matsueda S | 2012 | Exp Ther Med2012，3，3： | 1 |
| 14 | Effective Carbon and nitrogen sequestrations by soil Amendments of charcoal 显示文摘 | Yazawa Y Asakawa D Matsueda D | 2006 | Journal of Arid Land Studies2006，15，4： | 1 |
| 15 | Sinistral portal hypertension after pancreaticoduodenectomy with splenic vein ligation显示文摘 | Ono Y Matsueda K Koga R | 2015 | Br J Surg2015，102，3： | 1 |
| 16 | Overexpression of vascular permeability factor (VPF/ VEGF) and its endothelial cell receptors in delayed hypersensitivity skin reactions显示文摘 | Brown LF Olbricht SM Berse B Jackman RW Matsueda G Tognazzi KA | 1995 | J Immunol1995，154，6： | 1 |
| 17 | Direct measure- ment of nitric oxide in the gastrie mucosa: evidence of in- ereased genera - tion of nitric oxide in adapfirecytopretion 显示文摘 | Matsueda K Muraoka A Shoda R | 1994 | Gastroenterelogy1994，106，： | 1 |
| 18 | The cause of nontumorous defects of portal perfusion in the hepatic hilum revealed by CT during arterial portography显示文摘 | Yamagami T Arai Y Matsueda K | 1999 | AJR1999，172，2： | 1 |
| 19 | Blocking Predictability in operational medium-range ensemble forecast 显示文摘 | Matsueda M | 2009 | SOLA2009，5，： | 1 |
| 20 | The cause of nontumorous defects of portal perfusion in the hepatic hilum revealed by CT during arterial portography显示文摘 | Arai Y Matsueda K | 1999 | AJR1999，172，2： | 1 |
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