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| 1 | High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound显示文摘AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) and associated outcomes.METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras(era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era(era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively.RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3(P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3(P < 0.001) but not between eras 1 and 2(P = 0.028) or 1 and 3(P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation(P ≤ 0.007) as was the anesthesia-only time(P ≤ 0.001).CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation. | Roman Schumann Nikola S Natov Klifford A Rocuts-Martinez Matthew D Finkelman Tom V Phan Sanjay R Hegde Robert M Knapp | 2016 | World Journal of Gastroenterology2016，22，47： | 9 |
| 2 | Epistaxis in end stage liver disease masquerading as severe upper gastrointestinal hemorrhage显示文摘AIM:To describe the prevalence,diagnosis,treatment,and outcomes of end stage liver disease(ESLD) patients with severe epistaxis thought to be severe upper gastrointestinal hemorrhage(UGIH).METHODS:This observational single center study included all consecutive patients with ESLD and epistaxis identified from consecutive subjects hospitalized with suspected UGIH and prospectively enrolled in our databases of severe UGIH between 1998 and 2011.RESULTS:A total of 1249 patients were registered for severe UGIH in the data basis,461(36.9%) were cirrhotics. Epistaxis rather than UGIH was the bleeding source in 20 patients. All patients had severe coagulopathy. Epistaxis was initially controlled in all cases. Fifteen(75%) subjects required posterior nasal packing and 2(10%) embolization in addition to correction of coagulopathy. Five(25%) patients died in the hospital,12(60%) received orthotopic liver transplantation(OLT),and 3(15%) were discharged without OLT. The mortality rate was 63% in patients without OLT.CONCLUSION:Severe epistaxis in patients with ESLD is(1) a diagnosis of exclusion that requires upper endoscopy to exclude severe UGIH;and(2) associated with a high mortality rate in patients not receiving OLT. | Marine Camus Dennis M Jensen Jason D Matthews Gordon V Ohning Thomas O Kovacs Rome Jutabha Kevin A Ghassemi Gustavo A Machicado Gareth S Dulai | 2014 | World Journal of Gastroenterology2014，20，38： | 3 |
| 3 | Landscape features and weather influence nest survival of a ground-nesting bird of conservation concern,the greater sage-grouse,in humanaltered environments显示文摘Introduction:Ground-nesting birds experience high levels of nest predation.However,birds can make selection decisions related to nest site location and characteristics that may result in physical,visual,and olfactory impediments to predators.Methods:We studied daily survival rate[DSR]of greater sage-grouse(Centrocercus urophasianus)from 2008 to 2010 in an area in Wyoming experiencing large-scale alterations to the landscape.We used generalized linear mixed models to model fixed and random effects,and a correlation within nesting attempts,individual birds,and years.Results:Predation of the nest was the most common source of nest failure(84.7%)followed by direct predation of the female(13.6%).Generally,landscape variables at the nest site(≤30 m)were more influential on DSR of nests than features at larger spatial scales.Percentage of shrub canopy cover at the nest site(15-m scale)and distances to natural gas wells and mesic areas had a positive relationship with DSR of nests,whereas distance to roads had a negative relationship with DSR of nests.When added to the vegetation model,maximum wind speed on the day of nest failure and a 1-day lag in precipitation(i.e.,precipitation the day before failure)improved model fit whereby both variables negatively influenced DSR of nests.Conclusions:Nest site characteristics that reduce visibility(i.e.,shrub canopy cover)have the potential to reduce depredation,whereas anthropogenic(i.e.,distance to wells)and mesic landscape features appear to facilitate depredation.Last,predators may be more efficient at locating nests under certain weather conditions(i.e.,high winds and moisture). | Stephen L Webb Chad V Olson Matthew R Dzialak Seth M Harju Jeffrey B Winstead Dusty Lockman | 2012 | Ecological Processes2012，1，1： | 2 |
| 4 | Crystal doping aided by rapid expansion of supercritical solutions 显示文摘 | Chandra V Matthew J M Thomas E N | 2002 | AAPS Pharm-SciTech2002，3，4： | 1 |
| 5 | Middle ear electromagnetic semi - implantable hearing device : resuhs of the phase II SOUNDTEC direct system clinical trial 显示文摘 | Hough J V Matthews P Wood M W | 2002 | Otol Neurotol2002，23，6： | 1 |
| 6 | Laser capture microdissection (LCM) and comparative microarray expression analysis of syncytial cells isolated from incompatible and compatible soybean (Glycine max) roots infected by soybean cyst nematode (Heterodera glycines)显示文摘 | Klink V P Overall C C Alkharouf N MacDonald M H Matthews B F | | 0，，06： | 1 |
| 7 | Data mining for simple sequence repeats in expressed sequence tags from barley,maize,rice,sorghum and wheat显示文摘 | Kantety R V Rota M L Matthews D E | 2002 | Plant Mol Biol2002，48，： | 1 |
| 8 | Data mining for simple sequence repeats in expressed sequence tags from barley显示文摘 | Kantety R V La Rota M Matthews D E | 2002 | Plant Mol Biol2002，48，56： | 1 |
| 9 | Data mining for simple sequence repeats in expressed sequence tags from barley, maize, rice, sorghum and wheat 显示文摘 | KANTETY R V LA ROTA M MATTHEWS D E | 2002 | Plant Molecular Biology2002，48，5： | 1 |
| 10 | Prioritizing abandoned coal mine reclamation projects within the contiguous United States using Geographic information system extrapolation显示文摘 | Yuri G~ Andrew V Matthew R and Erica M | 2003 | Environmental Management2003，32，： | 1 |
| 11 | Conformationally mobile wide rim carbamoylmethy-lphosphine oxide(CMPO)-calixarenes显示文摘 | Matthews S E Saadioui M Bohmer V | 1999 | Prakt Chem1999，341，： | 1 |
| 12 | 查看详情显示文摘 | Matthews D L Campbell E M Ceglio N M Hermes G Kauffman R Koppel L Lee R Manes K Rupert V Slivinsky W Turner R Ze F | | 0，，： | 1 |
| 13 | Data mining for simple sequence repeats in expressed sequence tags from barley, maize, rice, sorghum and wheat显示文摘 | Kantety R V Rota M L Matthews D E | 2002 | Plant Mol Biol2002，48，： | 1 |
| 14 | Laser capture microdissection (LCM) and expression analyses of Glycine max (soybean) syncytium containing root regions formed by the plant pathogen Heterodera glycines (soybean cyst nematode)显示文摘 | Klink V P Alkharout N MacDonald M Matthews B | | 0，，： | 1 |
| 15 | Data mining for simple sequence repeats in expressed sequence tags from barley, maize, rice, sorghum and wheat显示文摘 | Kantety R V La Rota M Matthews D E Sorrells M E | 2002 | Plant Mol Biol2002，48，： | 1 |
| 16 | Data mining for simple sequence repeats in expressed sequence tags from barley, maize, rice, sorghum and wheat 显示文摘 | KANTETY R V LA ROTA M MATTHEWS D E | 2002 | Plant Molecular Bi- ology2002，48，： | 1 |
| 17 | Data mining for simple sequence repeats in expressed sequence tags from barley, maize, riee, sorghum and wheat显示文摘 | Kantety R V Rota M L Matthews D E | 2002 | Plant Molecular Biology2002，48，： | 1 |
| 18 | Data mining of simple sequence repeats in expressed sequence tags from barley, maize, rice, sorghum and wheat显示文摘 | KANTETY R V LA ROTA M MATTHEWS D E SORRELLS M E | 2002 | Plant Molecular Biology2002，148，56： | 1 |
| 19 | Risk factors affecting operating approach,conversion,and morbidity for adrenalectomy:a single institusion series of 402patients显示文摘 | Bittner J G 4th Gershuni V M Matthews B D | 2013 | Surg Endosc2013，7，27： | 1 |
| 20 | Data mining for simple sequence repeats in expressed sequence tags from barley, maize, rice, sorghum, and wheat显示文摘 | Kantety R V Rota M L Matthews D E | 2002 | Plant Mol Biol2002，48，4： | 1 |
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