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| 1 | Current status of ultrasound-guided surgery in the treatment of breast cancer显示文摘The primary goal of breast-conserving surgery(BCS) is to obtain tumour-free resection margins. Margins positive or focally positive for tumour cells are associated with a high risk of local recurrence, and in the case of tumour-positive margins, re-excision or even mastectomy are sometimes needed to achieve definite clear margins. Unfortunately, tumour-involved margins and re-excisions after lumpectomy are still reported in up to 40% of patients and additionally, unnecessary large excision volumes are described. A secondary goal of BCS is the cosmetic outcome and one of the main determinants of worse cosmetic outcome is a large excision volume. Up to 30% of unsatisfied cosm-etic outcome is reported. Therefore, the search for better surgical techniques to improve margin status, excision volume and consequently, cosmetic outcome has continued. Nowadays, the most commonly used localization methods for BCS of non-palpable breast cancers are wire-guided localization(WGL) and radioguided localization(RGL). WGL and RGL are invasive procedures that need to be performed pre-operatively with technical and scheduling difficulties. For palpable breast cancer, tumour excision is usually guided by tactile skills of the surgeon performing 'blind' surgery. One of the surgical techniques pursuing the aims of radicality and small excision volumes includes intraoperative ultrasound(IOUS). The best evidence available demonstrates benefits of IOUS with a significantly high proportion of negative margins compared with other localization techniques in palpable and non-palpable breast cancer. Additionally, IOUS is non-invasive, easy to learn and can centralize the tumour in the excised specimen with low amount of healthy breast tissuebeing excised. This could lead to better cosmetic results of BCS. Despite the advantages of IOUS, only a small amount of surgeons are performing this technique. This review aims to highlight the position of ultrasoundguided surgery for malignant breast tumours in the search for better oncological and cosmetic outcomes. | José H Volders Max H Haloua Nicole MA Krekel Sybren Meijer Petrousjka M van den Tol | 2016 | World Journal of Clinical Oncology2016，7，1： | 6 |
| 2 | Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy显示文摘 | Uta Drebber Max Lay Inga Wedemeyer Daniel Vallb?hmer Elfriede Bollschweiler Jan Brabender Stefan M?nig Arnulf H?lscher Hans Dienes Margarete Odenthal | 2011 | International Journal of Oncology2011，，： | 2 |
| 3 | Size-controlled Hydroxyapatite Nanoparticles as Self-organize Organic-inorganic Composite Materials显示文摘 | Viorel M R Chuen H N Max W | 2005 | Biomaterials2005，26，26： | 1 |
| 4 | Phylogenetic study on Shiraia bambusicola by rDNA sequence analyses显示文摘 | CHENG T F JIA X M MAX H | 2004 | J Basic Microbiol2004，44，5： | 1 |
| 5 | Bimetallic carbide nanocomposite enhanced Pt catalyst with high activity and stability for the oxygen reduction reaction显示文摘 | MAX M MENG H CAI M | | 0，，： | 1 |
| 6 | Writing on dirty paper显示文摘 | Max H Costa M | 1983 | IEEE Transactions on Information Theory1983，29，3： | 1 |
| 7 | Writing on dirty paper显示文摘 | Max H M Costa | 1983 | IEEE Transactions on Information Theory1983，29，3： | 1 |
| 8 | Computer-aided diagnosis in chest radiography 显示文摘 | Bram V G Bart M H Max A | 2001 | IEEE Transactions on Medical Imaging2001，20，12： | 1 |
| 9 | Carbonhydrate-Reaction,pore-forming outer membrane protein of Aeromonas hydrophila显示文摘 | Quinn D M Quinn H Max A H | 1994 | Infect Immun1994，62，9： | 1 |
| 10 | A constitutive law for twinning dominated flow in magnesium显示文摘 | BARNETT M R DAVIES C H J MAX | 2005 | Scripta Materialia2005，52，7： | 1 |
| 11 | Magma Mixing Origin for the Aolunhua Porphyry Related to Mo-Cu Miner- alization, Eastern Central Asian Orogenic Belt显示文摘 | MAX H CHEN B YANG M C | 2013 | Gondwana Research2013，24，34： | 1 |
| 12 | Bioehar impact on de- velopment and productivity of pepper and tomato grown in ferti- gated soilless media 显示文摘 | Ellen R G Yael M H Max K | 2010 | Plant Soil2010，337，： | 1 |
| 13 | Si ze-controlled hydroxyapat it enanoparti cles as self-organized organic-inorganic composite materials显示文摘 | CHUEN H N MAX W | 2005 | Biomaterials2005，26，： | 1 |
| 14 | Nitrogen processing gra-dients in subsurface - flow treatment wetlands - influence of wastewater characteristics 显示文摘 | Tanner C C Kadlee R H Max M Gibbs | 2002 | Ecological Engineering2002，18，4： | 1 |
| 15 | Pilla- ring and Photocatalytic Property of Partially Substituted Layered Titanates, Naz Ti3-x M, 07 and Ks Ti4 x Mx 09 ( M= Mn, Fe, Co, Ni, Cu) 显示文摘 | MACHIDA M MAX M TANIGUCHI H etal | 2000 | J Mol Catal A: Chemical2000，155，： | 1 |
| 16 | Nitrogen processing gradients in subsurface-flow treatment wetlands-influence of wastewater characteristics显示文摘 | Tanner C C Kadlec R H Max M G | 2002 | Ecological Engineering2002，18，4： | 1 |
| 17 | Nitrogen processing gradients in subsurface flow treatment wetlands influence of wastewater characteristics显示文摘 | Tanner C C Kadlec R H Max M Gibbs | 2002 | Ecological Engineering2002，18，4： | 1 |
| 18 | The electrospray ionization-mass spectra of Radix et rhizoma rhei anthraquinones 显示文摘 | MAX H SHEN S HAN F M | 2006 | Journal of Hubei University ( Natural Science)2006，28，4： | 1 |
| 19 | Electrochemical investigation of electrocatalysts for the oxygen evolution reac- tion in PEM water eleetrolyzers 显示文摘 | SONG S D ZHANG H M MAX P | 2008 | International Journal of Hydrogen Energy2008，33，19： | 1 |
| 20 | Current surgical management of congenital diaphragmatic hernia: A report from the congenital diaphragmatic hernia study group显示文摘 | Reese H Clark William D Hardin Ronald B Hirschl Tom Jaksic Kevin P Lally Max R Langham Jay M Wilson | 1998 | Journal of Pediatric Surgery1998，，7： | 1 |
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