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| 1 | Vanishing bile duct syndrome in human immunodeficiency virus infected adults:A report of two cases显示文摘Vanishing bile duct syndrome(VBDS) is a group of rare disorders characterized by ductopenia,the progressive destruction and disappearance of intrahepatic bile ducts leading to cholestasis.Described in association with medications,autoimmune disorders,cancer,transplantation,and infections,the specific mechanisms of disease are not known.To date,only 4 cases of VBDS have been reported in human immunodeficiency virus(HIV) infected patients.We report 2 additional cases of HIV-associated VBDS and review the features common to the HIV-associated cases.Presentation includes hyperbilirubinemia,normal liver imaging,and negative viral and autoimmune hepatitis studies.In HIV-infected subjects,VBDS occurred at a range of CD4+ T-cell counts,in some cases following initiation or change in antiretroviral therapy.Lymphoma was associated with two cases;nevirapine,antibiotics,and viral co-infection were suggested as etiologies in the other cases.In HIV-positive patients with progressive cholestasis,early identification of VBDS and referral for transplantation may improve outcomes. | Ana Paula Oppenheimer Christopher Koh Mary McLaughlin John C Williamson Thomas D Norton Jennifer Laudadio Theo Heller David E Kleiner Kevin P High Caryn G Morse | 2013 | World Journal of Gastroenterology2013，19，1： | 8 |
| 2 | Mechanisms of removal of heavy metals from water by ionizing radiation显示文摘 | Malmax C McLaughlin A Willian L | 1998 | Radiation Physics and Chemistry1998，53，2： | 2 |
| 3 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 4 | Extraction and separation of urinary catecholamines as their diphenyl boronate complexes using C 18 solid-phase extraction sorbent and high-performance liquid chromatography显示文摘 | Talwar D Williamsou C McLaughlin A | 2002 | Chromatogr B2002，769，2： | 1 |
| 5 | Microdialysis sampling with online microbore HPLC for the determination of tirapazamine and its reduced metabolites in rats显示文摘 | McLaughlin K J Faibushevich A A Lunte C E | 2000 | Analyst2000，125，1： | 1 |
| 6 | Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells显示文摘 | Radu C G Nijagal A McLaughlin J | 2005 | Proc Natl Acad Sci USA2005，102，5： | 1 |
| 7 | Fetal growth indicators and perfluorinated chemicals: a study in the Danish National Birth Cohort 显示文摘 | Fei C McLaughlin J K Tarone R E | 2008 | American journal of epidemiology2008，168，1： | 1 |
| 8 | Clinieal efficacy of two hypocaloric diets that vary in overweight patients with type 2 diabetes: comparison of moderate fat versus carbohydrate reductions显示文摘 | McLaughlin T Carter S Lamendola C | 2007 | Diabetes Care2007，30，7： | 1 |
| 9 | Strategies for globalizing service operations 显示文摘 | McLaughlin C P Fitzsimmons J A | 1996 | International Journal of Service Industry1996，7，4： | 1 |
| 10 | Mecha- nisms and responses of a single dielectric barrier discharge plas- ma actuator: plasma morphology显示文摘 | Enloe C L McLaughlin T E VanDyken R D | 2004 | AIAA Journal2004，42，3： | 1 |
| 11 | Flavonoids and the risk of renal cell carcinoma显示文摘 | Bosetti C Rossi M Mclaughlin J K | 2007 | Cancer Epidemiol Biomarkers Prev2007，16，1： | 1 |
| 12 | Basis mismatch in a compressively sampled photonic link 显示文摘 | McLaughlin C V Nichols J M Bucholtz F | 2013 | IEEE Photonics Technology Letters2013，25，23： | 1 |
| 13 | Foren-sic surface metrology : Tool mark evidence 显示文摘 | GAMBINO C MCLAUGHLIN P KUO L | 2011 | Scan-ning2011，33，5： | 1 |
| 14 | Satellite Formation Flying Design and Evolution 显示文摘 | Chris S Richard B McLaughlin C A | 2001 | Journal of Spacecraft and Rockets2001，38，2： | 1 |
| 15 | A parallel decoder for low latency decoding of turbo product codes显示文摘 | Argon C McLaughlin S W | 2002 | IEEE Communications Letters2002，6，2： | 1 |
| 16 | Differentiation between obesity and insulin resistance in the association with C-reactive protein 显示文摘 | McLaughlin T Abbasi F Lamendola C | 2002 | Circttlation2002，106，23： | 1 |
| 17 | Satellite formation flying design and evolution显示文摘 | Sabol C Bums R McLaughlin C A | 2001 | Journal of Spacecraft and Rockets2001，38，2： | 1 |
| 18 | Biological control of postharvcst diseases of grape,peach,and apple with yeasts Kloeckera apiculata and Candida guilliermondii显示文摘 | McLaughlin R J Wilson C L Dorby S | | 0，，05： | 1 |
| 19 | Smallest algae thrive as the Arctic Ocean freshens显示文摘 | Li W K W Mclaughlin F A Lovejoy C | | 0，，5952： | 1 |
| 20 | Time-correlated force production measurements of the dielectric harrier dis- charge plasma aerodynamic actuator 显示文摘 | Enloe C L Mcharg M G McLaughlin T E | 2008 | Journal of Applied Physics2008，103，7： | 1 |
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