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8367篇 您的检索式:作者名="Miller D"
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1Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) is the most common liver malignancy worldwide and a major cause of cancer-related mortality for which liver resection is an important curative-intent treatment option. However, many patients present with advanced disease and with underlying chronic liver disease and/or cirrhosis, limiting the proportion of patients who are surgical candidates. In addition, the development of recurrent or de novo cancers following surgical resection is common. These issues have led investigators to evaluate the benefit of neoadjuvant and adjuvant treatment strategies aimed at improving resectability rates and decreasing recurrence rates. While high-level evidence to guide treatment decision making is lacking, recent advances in locoregional and systemic therapies, including antiviral treatment and immunotherapy, raise the prospect of novel approaches that may improve the outcomes of patients with HCC. In this review, we evaluate the evidence for various neoadjuvant and adjuvant therapies and discuss opportunities for future clinical and translational research.Clifford Akateh Sylvester M Black Lanla Conteh Eric D Miller Anne Noonan Eric Elliott Timothy M Pawlik Allan Tsung Jordan M Cloyd 2019World Journal of Gastroenterology2019,25,28:16
2High-Frequency Rayleigh-Wave Method显示文摘High-frequency (≥2 Hz) Rayleigh-wave data acquired with a multichannel recording system have been utilized to determine shear (S)-wave velocities in near-surface geophysics since the early 1980s. This overview article discusses the main research results of high-frequency surface-wave techniques achieved by research groups at the Kansas Geological Survey and China University of Geosciences in the last 15 years. The multichannel analysis of surface wave (MASW) method is a non-invasive acoustic approach to estimate near-surface S-wave velocity. The differences between MASW results and direct borehole measurements are approximately 15% or less and random. Studies show that simultaneous inversion with higher modes and the fundamental mode can increase model resolution and an investigation depth. The other important seismic property, quality factor (Q), can also be estimated with the MASW method by inverting attenuation coefficients of Rayleigh waves. An inverted model (S-wave velocity or Q) obtained using a damped least-squares method can be assessed by an optimal damping vector in a vicinity of the inverted model determined by an objective function, which is the trace of a weighted sum of model-resolution and model-covariance matrices. Current developments include modeling high-frequency Rayleigh-waves in near-surface media, which builds a foundation for shallow seismic or Rayleigh-wave inversion in the time-offset domain; imaging dispersive energy with high resolution in the frequency-velocity domain and possibly with data in an arbitrary acquisition geometry, which opens a door for 3D surface-wave techniques; and successfully separating surface-wave modes, which provides a valuable tool to perform S-wave velocity profiling with high-horizontal resolution.Richard D Miller 徐义贤 罗银河 陈超 刘江平 Julian Ivanov 2009Journal of China University of Geosciences2009,20,3:2
3Critical Evaluation of Pulmonary Contusion in the Early Post-Traumatic Period: Risk of Assisted Ventilation显示文摘Hamrick Miller C Duhn Ryan D Ochsner M Gage 2009The American Surgeon2009,,11:2
4Hepatocellular carcinoma locoregional therapies:Outcomes and future horizons显示文摘Hepatocellular carcinoma(HCC)is the most common primary cancer of the liver and has an overall five-year survival rate of less than twenty percent.For patients with unresectable disease,evolving liver-directed locoregional therapies provide efficacious treatment across the spectrum of disease stages and via a variety of catheter-directed and percutaneous techniques.Goals of locoregional therapies in HCC may include curative intent in early-stage disease,bridging or downstaging to surgical resection or transplantation for early or intermediate-stage disease,and local disease control and palliation in advanced-stage disease.This review explores the outcomes of chemoembolization,bland embolization,radioembolization,and percutaneous ablative therapies.Attention is also given to prognostic factors related to each of the respective techniques,as well as future directions of locoregional therapies for HCC.Mina S Makary Stuart Ramsell Eric Miller Eliza W Beal Joshua D Dowell 2021World Journal of Gastroenterology2021,27,43:2
5Evaluation and Optimization of DNA Extraction and Purification Procedures for Soil and Sediment Samples 显示文摘D N Miller J E Bryant E L Madsen and W C Ghiorse 1999Applied and environmental Microbiolog1999,65,:2
6T lymphocyte-directed gene therapy for ADA-SCID:initial trial results after 4 years显示文摘Blaese R M Culver K W Miller A D 1995Science1995,270,5235:2
7视网膜单细胞成像技术研究显示文摘建立了一台基于37单元变形镜、Shack-hartman波前像差传感器和12位科研级CCD相机的自适应光学视网膜相机。采用一个中心波长为679nm的超辐射二极管(SLD)作为相机的光源,通过将超辐射二极管和多模光纤耦合,显著减小了SLD光源的空间相干性,从而消除了散斑噪声对成像的影响。多模光纤的输出提供了一种高亮度、均匀照明的光源,使人眼视网膜单细胞成像的速度达到4.8幅 秒。屈军乐 JONNAL R S THORN K E MILLER D T 2004激光生物学报2004,13,3:2
8Base stock level determination for high cost low demand critical repairable spares 显示文摘Dhakar T S Schmidt C P Miller D M 1994Computers and Operations Research1994,21,:2
9Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections显示文摘York E Miller Lori D Dwyer-Nield Robert L Keith Mysan Le Wilbur A Franklin Alvin M Malkinson 2003Cancer Letters2003,,2:2
10Solidstate low-loss intracavity saturable absorber for Nd:YLF lasers:An A-FPSA显示文摘KELLER U MILLER D A B BOYD G D 1992Opt Lett1992,17,7:2
11Reoperation for prosthetic aortic valve obstruction in the era of echocardiography: trends in diagnostic testing and comparison with surgical findings显示文摘Steven E Girard Fletcher A Miller Thomas A Orszulak Charles J Mullany Samantha Montgomery William D Edwards Henry D Tazelaar Joseph F Malouf A.Jamil Tajik 2001Journal of the American College of Cardiology2001,,2:2
12Anti-hypertensive drugs in children and adolescents显示文摘Worldwide the prevalence of essential hypertension inchildren and adolescents continues to increase. Tradi-tionally providers have used 'off-label' drugs to treatpediatric hypertension, meaning that rigorous clinicaltrials of these drugs have not been specifically per-formed in pediatric patient populations. Consequentlyproviders have extrapolated dosing, safety and efficacyfrom trials in adults. This practice is sub-optimal as chil-dren demonstrate unique differences in drug metabo-lism and response. Use of unstudied or understudieddrugs increases risk of adverse events and/or can leadto sub-optimal efficacy. Recognizing these concerns,regulatory agencies have created financial incentivesfor industry to conduct pediatric clinical trials. Theseincentives, coupled with the emerging pediatric hyper-tension epidemic, have spurred over 30 clinical trialsof anti-hypertensive drugs over the past 15 years andhave resulted in labeling of 10 new drugs by the UnitedStates Food and Drug Administration for treatment ofhypertension in children and adolescents. Unfortunatelythe financial incentive structures focus on newer drugsand drug classes. Consequently there is now a relativedearth of trial data for older but sometimes commonlyprescribed pediatric antihypertensive drugs. This article reviews recent pediatric antihypertensive drug trials with a focus on trial design and endpoints, drug dosing, safety, efficacy and specific drug indications. We also review the available data and experience for some of the more commonly prescribed, but less well studied 'older' pediatric antihypertensive drugs.Patricia Y Chu Michael J Campbell Stephen G Miller Kevin D Hill 2014World Journal of Cardiology2014,6,5:2
13Automatic-repeat-request error-control schemes显示文摘LIN S COSTELLO D J MILLER M J 1984IEEE Commun Mag1984,22,:2
14The CECE Alternative for Upgrading Detritiation in Heavy Water Nuclear Reactor and for Tritium Recovery in Fusion Reactor显示文摘Spagnolo D A Miller A I 1995Fusion Technol1995,28,:2
15Rating chronic medical illness burden in geropsyehiatric practice and research: application of the Cumulative Illness Rating Scale显示文摘Miller M D Paradis C F Houck P R 1992Psychiatry Res1992,41,3:1
16The AutoPap system for p rimary screening in cervical cytology 显示文摘Wilbur D C Prey M U Miller W M 2008Acta Cytol2008,42,5:1
17Natural herbicide potential of alfalfa residues on selected weed species显示文摘Chung I M Miller D A 1995Agron J1995,87,:1
18Solventless determination of caffeine in beverages using solid-phase microextraction with fused-silica fibers显示文摘Hawthorne S B Miller D J Pawliszyn J 1992Journal of chromatography1992,603,:1
19Wetting characteristics of newly developed water-repellent material 显示文摘Yamauchi G Miller J D Saito H 1996Colloid and Surface A-Physicochemical and Engineering Aspects1996,116,12:1
20Gapped BLAST and PSI-BLAST: a new generation of protein database searchprograms显示文摘 Madden T L Schaffer A A Zhang J Zhang Z Miller W Lipman D J 1997Nucle ic Acids Res1997,25,:1
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