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| 1 | Mitochondrial GPX1 silencing triggers differential photosynthesis impairment in response to salinity in rice plants显示文摘The physiological role of plant mitochondrial glutathione peroxidases is scarcely known. This study attempted to elucidate the role of a rice mitochondrial isoform(GPX1) in photosynthesis under normal growth and salinity conditions. GPX1 knockdown rice lines(GPX1s) were tested in absence and presence of 100 mM NaCl for 6 d.Growth reduction of GPX1 s line under non-stressful conditions, compared with non-transformed(NT) plants occurred in parallel to increased H_2O_2 and decreased GSH contents. These changes occurred concurrently with photosynthesis impairment, particularly in Calvin cycle's reactions, since photochemical efficiency did not change.Thus, GPX1 silencing and downstream molecular/metabolic changes modulated photosynthesis differentially. In contrast, salinity induced reduction in both phases of photosynthesis, which were more impaired in silenced plants.These changes were associated with root morphology alterations but not shoot growth. Both studied lines displayed increased GPX activity but H_2O_2 content did not change in response to salinity. Transformed plants exhibited lower photorespiration, water use efficiency and root growth, indicating that GPX1 could be important to salt tolerance. Growth reduction of GPX1 s line might be related to photosynthesis impairment, which in turn could have involved a cross talk mechanism between mitochondria and chloroplast originated from redox changes due to GPX1 deficiency. | Yugo Lima-Melo Fabricio E.L.Carvalho Márcio O.Martins Gisele Passaia Rachel H.V.Sousa Milton C.Lima Neto Márcia Margis-Pinheiro Joaquim A.G.Silveira | 2016 | Journal of Integrative Plant Biology2016，58，8： | 7 |
| 2 | Endocrine radionuclide scintigraphy with fusion single photon emission computed tomography/computed tomography显示文摘AIM: To review the benefits of single photon emission computed tomography(SPECT)/computed tomography(CT) hybrid imaging for diagnosis of various endocrine disorders.METHODS: We performed MEDLINE and Pub Med searches using the terms: 'SPECT/CT'; 'functional anatomic mapping'; 'transmission emission tomography'; 'parathyroid adenoma'; 'thyroid cancer'; 'neuroendocrine tumor'; 'adrenal'; 'pheochromocytoma'; 'paraganglioma'; in order to identify relevant articles published in English during the years 2003 to 2015. Reference lists from the articles were reviewed to identify additional pertinent articles. Retrieved manuscripts(case reports, reviews, meta-analyses and abstracts) concerning the application of SPECT/CT to endocrine imaging were analyzed to provide a descriptive synthesis of the utility of this technology.RESULTS: The emergence of hybrid SPECT/CT camera technology now allows simultaneous acquisition of combined multi-modality imaging, with seamless fusion of three-dimensional volume datasets. The usefulness of combining functional information to depict the biodistribution of radiotracers that map cellular processes of the endocrine system and tumors of endocrine origin, with anatomy derived from CT, has improved the diagnostic capability of scintigraphy for a range of disorders of endocrine gland function. The literature describes benefits of SPECT/CT for ^(99m)Tc-sestamibi parathyroid scintigraphy and ^(99m)Tc-pertechnetate thyroid scintigraphy, ^(123)I- or ^(131)I-radioiodine for staging of differentiated thyroid carcinoma, ^(111)In- and ^(99m)Tclabeled somatostatin receptor analogues for detection of neuroendocrine tumors, ^(131)I-norcholesterol(NP-59) scans for assessment of adrenal cortical hyperfunction, and ^(123)I- or ^(131)I-metaiodobenzylguanidine imaging for evaluation of pheochromocytoma and paraganglioma.CONCLUSION: SPECT/CT exploits the synergism between the functional information from radiopharmaceutical imaging and anatomy from CT, translating to improved diagnostic accuracy and meaningful impact on patient care. | Ka-Kit Wong Arpit Gandhi Benjamin L Viglianti Lorraine M Fig Domenico Rubello Milton D Gross | 2016 | World Journal of Radiology2016，8，6： | 3 |
| 3 | An inexpensive and simple method for DNA purifications on silica particles 显示文摘 | Carter M J Milton I D | 1993 | Nucleic Acids Res1993，21，4： | 2 |
| 4 | Spectral classification of water masses under the influence of the Amazon River plume显示文摘The large amount of dissolved and particulate material discharged by the Amazon River into the Equatorial Atlantic Ocean cause distinct spectral response of its waters as compared to the nearby ocean waters. This paper shows the application of K-means clustering algorithm for classifying water masses in the region under the Amazon River plume influence according to their spectral behavior. Salinity and temperature data from 67 oceanographic stations were related to Sea-viewing Wide Field-of-view Sensor (SeaWiFS) remote sensing reflectances values and the following bio-optical products: (i) chlorophyll-a concentration, (ii) water attenuation coefficient and (iii) absorption coefficient for dissolved and detrital material. Four different water masses were identified such as: (1) oceanic water, (2) intermediate oceanic water, (3) intermediate river plume water and (4) Amazon River plume water. The spectral behavior of these water masses allowed concluding that the main active optical component of the waters in the region is the colored dissolved organic matter originated mostly from the Amazon River. | Gustavo Souto Fontes Molleri Milton Kampel Evlyn Mrcia Leo de Moraes Novo | 2010 | Acta Oceanologica Sinica2010，29，3： | 2 |
| 5 | Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct 显示文摘 | Necula M Kayed R Milton S | 2007 | J Biol Chem2007，282，10： | 1 |
| 6 | Evaluation of the intelisite capsule to deliver theophylline and frusemide tablets to the small intestine and colon显示文摘 | Clear N J Milton A Humphrey M | 2001 | Eur J Pharm Sci2001，13，4： | 1 |
| 7 | On Cloaking for Elasticity and Physical Equations with A Transformation Invariant Form 显示文摘 | Milton G W Briane M Willis J R | 2006 | New J Phys2006，8，： | 1 |
| 8 | PT-symmetric versus Hermitian formulations of quantum mechanics显示文摘 | BENDER C M CHEN Junhua MILTON K A | | 0，，： | 1 |
| 9 | A conceptual model of arid rangeland degradation 显示文摘 | Dean W R J du Plessis M A Siegfried W R | 1994 | Bioscience1994，44，： | 1 |
| 10 | Studies of Supported Nickel Cata- lysts by X-Ray Photoelectron and Ion Scattering Spectroscopies 显示文摘 | Milton Wu David M Hercules | 1979 | J Phy Chem1979，83，15： | 1 |
| 11 | Remote sensing of vegetation responses to natural and cultural environment condition显示文摘 | Milton N M Monat D A | | 0，，08： | 1 |
| 12 | A comparison of cadmium in ecosystems on metalliferous mine tailings in Wales and Ireland显示文摘 | MILTON A COOKE J A JOHNSON M S | 2004 | Water Air and Soil Pollution2004，153，1： | 1 |
| 13 | Neuroprotective sig- naling pathways are modulated by adenosine in the anoxia tolerant turtle显示文摘 | Nayak G H Prentice H M Milton S L | 2011 | J Cereb Blood Flow Metab2011，31，2： | 1 |
| 14 | Evaluation of the In- telisite capsule to deliver theophylline and frusemide tablets to the small intestine and colon 显示文摘 | Clear N J Milton A Humphrey M | 2001 | Eur J Pharm Sci2001，13，4： | 1 |
| 15 | Tissue gas levels as a index of the adequacy of circulation:the lateral circulation (delay phenomenon)显示文摘 | MEYERS M B CHERRY G MILTON S | 1972 | Surgery1972，71，： | 1 |
| 16 | PT- symmetric versus Hermitian formulations of quantum mechanics显示文摘 | Bender C M Chen J H Milton K A | 2006 | J Phys A2006，39，： | 1 |
| 17 | Radiocarbon dispersion around Canadian nuclear facilities显示文摘 | MILTON G M KRAMER S J BROWN R M | 1995 | Radiocarbon1995，37，2： | 1 |
| 18 | Rating Agencies in the Face of Regulation显示文摘 | Opp Christian C Opp Marcus M Harris Milton | 2013 | Journal of Financial Economies2013，108，1： | 1 |
| 19 | LPS signaling enhances hepatic fibrogenesis caused by experirnen- tal cholestasis in mice 显示文摘 | Isayarna F Hines IN Kremer M Milton R J Byrd CL Perry AW | 2006 | Am J Physiol Gastrointest Liver Physiol2006，290，6： | 1 |
| 20 | Kupffer cell and interleukin-12-dependent loss of natural killer T ceils in hepatosteatosis显示文摘 | Kremer M Thomas E Milton RJ | 2010 | Hepatology2010，51，1： | 1 |
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