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| 1 | Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy显示文摘Colorectal cancer(CRC)is a predominant life-threatening cancer,with liver and peritoneal metastases as the primary causes of death.Intestinal inflammation,a known CRC risk factor,nurtures a local inflammatory environment enriched with tumor cells,endothelial cells,immune cells,cancer-associated fibroblasts,immunosuppressive cells,and secretory growth factors.The complex interactions of aberrantly expressed cytokines,chemokines,growth factors,and matrix-remodeling enzymes promote CRC pathogenesis and evoke systemic responses that affect disease outcomes.Mounting evidence suggests that these cytokines and chemokines play a role in the progression of CRC through immunosuppression and modulation of the tumor microenvironment,which is partly achieved by the recruitment of immunosuppressive cells.These cells impart features such as cancer stem cell-like properties,drug resistance,invasion,and formation of the premetastatic niche in distant organs,promoting metastasis and aggressive CRC growth.A deeper understanding of the cytokineand chemokine-mediated signaling networks that link tumor progression and metastasis will provide insights into the mechanistic details of disease aggressiveness and facilitate the development of novel therapeutics for CRC.Here,we summarized the current knowledge of cytokine-and chemokine-mediated crosstalk in the inflammatory tumor microenvironment,which drives immunosuppression,resistance to therapeutics,and metastasis during CRC progression.We also outlined the potential of this crosstalk as a novel therapeutic target for CRC.The major cytokine/chemokine pathways involved in cancer immunotherapy are also discussed in this review. | Ajaz A.Bhat Sabah Nisar Mayank Singh Bazella Ashraf Tariq Masoodi Chandra P.Prasad Atul Sharma Selma Maacha Thasni Karedath Sheema Hashem Syed Besina Yasin Puneet Bagga Ravinder Reddy Michael P.Frennaux Shahab Uddin Punita Dhawan Mohammad Haris Muzafar A.Macha | 2022 | Cancer Communications2022，42，8： | 8 |
| 2 | Investigation on the process parameters of TIG-welded aluminum alloy through mechanical and microstructural characterization显示文摘Multi-pass TIG welding was conducted on plates(15×300×180 mm^(3))of aluminum alloy Al-5083 that usually serves as the component material in structural applications such as cryogenics and chemical processing industries.Porosity formation and solidification cracking are the most common defects when TIG welding Al-5083 alloy,which is sensitive to the welding heat input.In the experiment,the heat input was varied from 0.89 kJ/mm to 5 kJ/mm designed by the combination of welding torch travel speed and welding current.Tensile,micro-Vicker hardness and Charpy impact tests were executed to witness the impetus response of heat input on the mechanical properties of the joints.Radiographic inspection was performed to assess the joint’s quality and welding defects.The results show that all the specimens displayed inferior mechanical properties as compared to the base alloy.It was established that porosity was progressively abridged by the increase of heat input.The results also clinched that the use of medium heat input(1-2 kJ/mm)offered the best mechanical properties by eradicating welding defects,in which only about 18.26% of strength was lost.The yield strength of all the welded specimens remained unaffected indica ted no influence of heat input.Partially melted zone(PMZ)width also affected by heat input,which became widened with the increase of heat input.The grain size of PMZ was found to be coarser than the respective grain size in the fusion zone.Charpy impact testing revealed that the absorbed energy by low heat input specimen(welded at high speed)was greater than that of high heat input(welded at low speed)because of low porosity and the formation of equiaxed grains which induce better impact toughness.Cryogenic(-196℃)impact testing was also performed and the results corroborate that impact properties under the cryogenic environment revealed no appreciable change after welding at designated heat input.Finally,Macro and micro fractured surfaces of tensile and impact specimens were analyzed using Stereo and Scanning Electron Microscopy(SEM),which have supported the experimental findings. | Muhammad Samiuddin Jing-long Li Muhammad Taimoor Mohammad Nouman Siddiqui Sumair Uddin Siddiqui Jiang-tao Xiong | 2021 | Defence Technology(防务技术)2021，17，4： | 5 |
| 3 | HBsAg, HBcAg, and combined HBsAg/HBcAg-based therapeutic vaccines in treating chronic hepatitis B virus infection显示文摘BACKGROUND: As the host immunity is diminished in patients with chronic hepatitis B (CHB), different approaches have been used to up-regulate their immune responses to produce therapeutic effects. But, cytokines, growth factors and polyclonal immune modulators could not exhibit sufficient therapeutic effects in these patients. Immune therapy with HBV-related antigens (vaccine therapy) has been used in CHB patients. But there is a paucity of information about the design of HBV antigen-based immune therapy in these patients. DATA SOURCE: Preclinical and clinical studies on immune therapy with HBsAg-based vaccine, HBcAg and combination of HBsAg/HBcAg-based vaccines have been discussed. RESULTS: HBsAg-based prophylactic vaccine was used as an immune therapeutic agent in CHB patients; however, monotherapy with HBsAg-based immune therapy could not lead to sustained control of HBV replication and/or liver damages. HBsAg-based vaccine was used as a combination therapy with cytokines, growth factors, and antiviral drugs. HBsAg-based vaccine was also used for cell-based therapy. However, satisfactory therapeutic effects of HBsAg-based vaccine could not be documented in CHB patients. In the mean time, evidences have supported that HBcAg-specific immunity is endowed with antiviral and liver protecting capacities in CHB patients. Recent data concentrate on the clinical use of combined HBsAg- and HBcAg-based vaccines in CHB patients.CONCLUSION: Antigen-based immune therapy with HBV- related antigens may be an alternative method for the treatment of CHB patients but proper designs of antigens, types of adjuvants, dose of vaccinations, and routes of administration need further analyses for the development of an effective regimen of immune therapy against HBV. | Sheikh Mohammad Fazle Akbar Mamun Al-Mahtab Mohammad Helal Uddin Md. Sakirul Islam Khan | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，4： | 5 |
| 4 | A High Dielectric N-Type Small Molecular Acceptor Containing Oligoethyleneglycol Side-Chains for Organic Solar Cellst显示文摘 | Bomee Jang Changyeon Lee Young Woong Lee Donguk Kim Mohammad Afsar Uddin Felix Sunjoo Kim Bumjoon J. Kim Han Young Woo | 2018 | Chinese Journal of Chemistry2018，36，3： | 3 |
| 5 | 孟加拉的马缨丹对某些农作物的生长和种子萌发的异种克生现象(英文)显示文摘本试验观察马缨丹的提取物对6种常见农作物的生长抑制作用。在24小时光照,平均温度29°C条件下,观察纪录了不同浓度的马缨丹的提取物对农作物生长的影响效果。结果表明:不同浓度的马缨丹的提取物对农作物的根茎的萌发和生长及种子萌发有明显的抑制作用。生物测定表明提取物的浓度的抑制作用表现成比例现象,较高浓度的提取物有较强的抑制作用,较低浓度的提取物对作物生长有一定的刺激作用。这项研究表明提取物对农作物茎和种子的萌发有抑制作用,尤其对根和侧根有更明显的抑制作用。 | Romel Ahmed Mohammad Belal Uddin Mohammed AbuSayed Arfin Khan Sharif Ahmed Mukul Mohammed Kamal Hossain | 2007 | Journal of Forestry Research2007，18，4： | 2 |
| 6 | Effects of stand characteristics on tree species richness in and around a conservation area of northeast Bangladesh显示文摘We investigated the effect of tree cover,forest patch and disturbances on tree species richness in a highly diverse conservation area of northeast Bangladesh.A systematic sampling protocol was adopted and 80 sub-plots from twenty five 1 ha plots were used for the vegetation survey.Linear regression analysis was performed to understand the effect of patch area,disturbances and tree cover on tree species richness.Ordination using Redundancy analysis(RDA) and Non-metric Multi Dimensional Scaling(NMDS) were also performed to explore the tree species compositional similarities along the stand characteristics gradient and locations of the sample plots.Our study revealed that,forest patch size has greater influence on species richness.Areas with medium level of disturbances have shown greater species richness.In constrained ordination the selected explanatory variables regulated the richness of common species.Our findings can be useful for better forest management and restoration of landscapes of conservation needs using ecologically important species. | Muha Abdullah Al PAVEL SharifA.MUKUL Mohammad Belal UDDIN Kazuhiro HARADA Mohammed A.S.ARFIN KHAN | 2016 | Journal of Mountain Science2016，13，6： | 2 |
| 7 | Assaying the allelopathic effects of Eucalyptus camaldulensis in a nursery bed incorporated with leaf litter显示文摘Allelopathic effects of Eucalyptus camaldulensis Dehnh. were confirmed in Petri dish and pot experiments in our previous studies. However, the degree to which such effects under controlled experiments exist in more complex ecological settings remains to be tested. Thus, the present study was carried out by incorporating different proportions of ground litter of E. camaldulensis in soil. The growth of three agricultural crops: falen(Vigna unguiculata(L.) Walp.), chickpea(Cicer arietinum L.), and arhor(Cajanus cajan(L.) Millsp.), and two tree species, kala koroi(Albizia procera(Roxb.) Benth.) and ipil ipil(Leucaena leucocephala(Lam.) de Wit) were tested. There were inhibitory effects of leaf litter on germination, shoot and root growth, leaf number, and collar diameter as well as a reduction of nodulation by legume crops(25–80%reduction). The extent of the effects was dependent on the proportion of leaf litter, the species and the type of traits. In contrast to shoot growth, the effect on root growth was more severe. No effect on germination was found with the agriculture crops while the two tree species showed reduced germination. The effect was greater in the presence of higher proportions of leaf litter mixed in soil while in some cases lower proportions stimulated growth. Not all species were suppressed; A. procera, C. cajan, V. unguiculata showed compatible growth while C. arietinum and L.leucocephala were found incompatible. This study provides evidence that E. camaldulensis has allelopathic potential under field conditions and a careful selection of associated crops in agroforestry systems is highly recommended. | Romel Ahmed Mohammad Shafioul Alam Farid Uddin Ahmed M.K.Hossain | 2018 | Journal of Forestry Research2018，29，3： | 2 |
| 8 | Seedling response of three agroforestry tree species to phosphorous fertilizer application in Bangladesh: growth and nodulation capabilities显示文摘三倍的超级磷酸盐, TSP 化肥,被使用@80 kg · h −1 作为来源在六个月磷在在孟加拉国的苗床的 Albizia chinensis, Albizia saman 和 Pongamia pinnta 的旧 polybag 幼苗。幼苗生长和生节上的 P 化肥的效果与在不同收获间隔在未受精的土壤或在控制种的幼苗的相比。学习揭示了那,幼苗生长用 P 化肥的申请显著地被提高。生长在 A 的情况下被发现更显著。saman 和 P。pinnata,而它不是在 A 的情况下的显著、显示出的沮丧的生长。chinensis。学习也建议除了在 P 的情况下,生节也与 P 授精显著地以小瘤数字和尺寸被增加。pinnata。 | Mohammad Belal Uddin Sharif Ahmed Mukull Mohammed Abu Sayed Arfin Khan Mohammed Kamal Hossain | 2009 | Journal of Forestry Research2009，20，1： | 2 |
| 9 | 含羞草叶子提取物对常见农作物种子萌发生长的抑制作用(英文)显示文摘观察了含羞草叶子提取物对孟加拉常见农作物种子萌发生长的抑制作用。实验在27-30°C的室温和24小时的光照条件下进行。结果表明:不同浓度的含羞草叶子提取物明显影响所选的植物种子根,茎和侧根的延长和生长。生物学测定表明:高浓度(50%-100%)的提取物有较强的抑制作用。而低浓度(10%-25%)的提取物的抑制作用较弱。研究还显示,提取物对植物根和侧根的抑制作用比对种子萌发和茎的生长抑制作用更显著。图3表4参29。 | Mohammad Belal Uddin Romel Ahmed Sharif Ahmed Mukul Mohammed Kamal Hossain | 2007 | Journal of Forestry Research2007，18，2： | 2 |
| 10 | 采用SWOT分析法评价低影响开发模式在中国应用的可行性(英文)显示文摘采用SWOT分析方法对传统雨洪管理模式和低影响开发模式在我国应用的优势、劣势、机会和威胁进行评价.结果表明,传统雨洪管理模式存在诸多缺点,例如只针对雨水收集排放或只用于调蓄洪峰,未考虑雨水的原位入渗、面源污染控制、生态处理等;作为新型的雨洪综合管理模式,低影响开发模式存在诸多优势,例如在进行雨水水量控制的同时,可有效控制面源污染,且便于实施、建设费用低、管理维护方便等.同时,低影响开发模式已受到中国各级政府部门和广大从业者的广泛关注和重视,其在中国拥有广阔的应用前景. | 丁年 李子富 周晓琴 胡爱兵 白晓凤 Nazim Uddin Sayed Mohammad | 2014 | Journal of Southeast University(English Edition)2014，30，2： | 2 |
| 11 | Extraction of metal ions by emulsion liquid membrane using bi-functional surfactant:equilibrium and kinetic studies显示文摘 | Mohammad S Uddin Marimuthu Kathiresan | 2000 | Separation and Purification Technology2000，19，： | 1 |
| 12 | In vitro propagation of Stevia rebaudiana Bert in Bangladesh显示文摘 | Uddin Salim Mohammed Chowdhury Shaheed Hossain Mohammad Khan Mahfuzul Haque Muoztaba M | 2006 | African Journal of Biotechnology2006，5，13： | 1 |
| 13 | The implementation of faceted classification in web site searching and browsing显示文摘 | Mohammad Nasir Uddin Paul Janecek | 2007 | Online Information Review2007，，2： | 1 |
| 14 | Faceted classification in web information architecture ; A framework for using semantic web tools 显示文摘 | Mohammad Nasir Uddin Paul Janecek | 2007 | The Electronic Library2007，，2： | 1 |
| 15 | Early termination of immune tolerance state of hepatitis B virus infection explains liver damage显示文摘AIM: To assess an early termination of immune toler-ance state of chronic hepatitis B virus infection in Ban-gladesh and its clinical significance. METHODS: From a series of 167 treatment-naive chronic hepatitis B patients aged between 12 to 20 years(mean ± SD; 17.5 ± 2.8 years), percutaneous liver biopsies of 89 patients who were all hepatitis B e antigen negative at presentation were done. Of them, 81 were included in the study. They had persistently normal or raised serum alanine aminotransferase(ALT) values. A precore mutation(PCM) study was accom-plished in 8 patients who were randomly selected. RESULTS: Forty-four(53.7%) patients had significant necroinflammation(HAI-NI > 7), while significant fi-brosis(HAI-F ≥ 3) was seen in 15(18.5%) patients. Serum ALT(cut off 42 U/L) was raised in 29(35.8%) patients, while low HBV DNA load(< 105 copies/mL)was observed in 57(70.4%) patients. PCM was nega-tive in all 8 patients. CONCLUSION: This study indicates that the current concept of age-related immune tolerance state of HBV infection deserves further analyses in different popula-tion groups. | Mamun-Al-Mahtab Sheikh Mohammad Fazle Akbar Helal Uddin Sakirul Islam Khan Salimur Rahman | 2014 | World Journal of Hepatology2014，6，8： | 1 |
| 16 | Efficient Guide&Mode-Resonant tunable color filters显示文摘 | Mohammad Jalal Uddin Robert Magnusson | 2012 | IEEE Photonics Technology Letter2012，24，17： | 1 |
| 17 | Design of an automated secure garage sys- tem using license plate recognition technique显示文摘 | Afaz Uddin Ahmed Taufiq Mahmud Masum Mohammad Mahbubur Rahman | 2014 | International Journal of Intelligent Systems and Applications2014，6，2： | 1 |
| 18 | Flow and erosion at a bend in the braided Jamuna River显示文摘编织 Jamuna 河经常改变它的功课。有时,一条编织的河里的第二等的隧道作为一个单身者扮演线蜿蜒地流隧道。在现在的学习,被尝试了调查流动模式并且沿着 Jamuna 河在拐弯估计河岸侵蚀的率。三维(3D ) 流动速度用声学的 Doppler 当前的剖析程序(ADCP ) 被测量。近的河岸速度作为与节相比到 1.1 ~ 1.3 次被放大,这被发现平均速度。主导的第二等的水流在在上游的拐弯被发现。象第二等的水流的腐烂一样的进化不象它在实验室实验被发现一样是清楚的。它从在学习拐弯的侵蚀的更高的率的原因是 bankline 附近的倾斜的流动的流动过程的分析被揭示,放大的六次砍速度比批评砍 bankline 和充当向内部河岸或沙酒吧从外部河岸搬运代理人的沉积的第二等的水流附近的速度。基于流动过程,一个简化侵蚀预言模型被开发并且适用在选择拐弯估计侵蚀的率。最后预言的结果在沿着 Jamuna 河的另外的拐弯与在拐弯和所有可得到的数据的观察数据相比。 | Mohammad Nazim UDDIN Md.Munsur RAHMAN | 2012 | International Journal of Sediment Research2012，27，4： | 1 |
| 19 | The Efficacy of Deep Learning-Based Mixed Model for Speech Emotion Recognition显示文摘Human speech indirectly represents the mental state or emotion of others.The use of Artificial Intelligence(AI)-based techniques may bring revolution in this modern era by recognizing emotion from speech.In this study,we introduced a robust method for emotion recognition from human speech using a well-performed preprocessing technique together with the deep learning-based mixed model consisting of Long Short-Term Memory(LSTM)and Convolutional Neural Network(CNN).About 2800 audio files were extracted from the Toronto emotional speech set(TESS)database for this study.A high pass and Savitzky Golay Filter have been used to obtain noise-free as well as smooth audio data.A total of seven types of emotions;Angry,Disgust,Fear,Happy,Neutral,Pleasant-surprise,and Sad were used in this study.Energy,Fundamental frequency,and Mel Frequency Cepstral Coefficient(MFCC)have been used to extract the emotion features,and these features resulted in 97.5%accuracy in the mixed LSTM+CNN model.This mixed model is found to be performed better than the usual state-of-the-art models in emotion recognition from speech.It also indicates that this mixed model could be effectively utilized in advanced research dealing with sound processing. | Mohammad Amaz Uddin Mohammad Salah Uddin Chowdury Mayeen Uddin Khandaker Nissren Tamam Abdelmoneim Sulieman | 2023 | Computers, Materials & Continua2023，，1： | 1 |
| 20 | Automated robotic grinding by low-powered manipulator显示文摘 | Saeid Nahavandi Mohammad Jashim Uddin Yasuo Nasu Hieu Trinh Mozafar Saadat | 2006 | Robotics and Computer Integrated Manufacturing2006，，5： | 1 |
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