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| 1 | 静脉血栓栓塞症的抗血栓治疗:美国《胸科学》杂志指南显示文摘包括深静脉血栓和肺栓塞在内的静脉血栓栓塞症是癌症患者的主要并发症,发生率为4%~20%,并且是常见的潜在致命性急症。本文介绍了美国《胸科学》杂志指南中VET的抗血栓治疗的部分内容,其以第9版《美国胸内科医师学会循证临床实践指南》中的《静脉血栓栓塞症的抗血栓治疗:抗血栓治疗和阻止血栓形成》一文为参照,基于静脉血栓栓塞症治疗的Ⅲ期试验的发表年份,对口服抗凝剂(达比加群、利伐沙班、阿哌沙班、依度沙班)进行先后阐述(但是这一排序并不是指南专家组对药剂的优劣排序),以为临床医生提供参考。 | Kearon C Akl EA Ornelas J Blaivas A Jimenez D Bounameaux H Huisman M King CS MorrisT Sood N Stevens SM Vintch JRE Wells P Woller SC Moores CL 本刊编辑部 | 2016 | 中国全科医学2016，19，9： | 10 |
| 2 | Systems biology approaches for studying the pathogenesis of non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD) is a progressive disease of increasing public health concern.In western populations the disease has an estimated prevalence of 20%-40%,rising to 70%-90% in obese and type Ⅱ diabetic individuals.Simplistically,NAFLD is the macroscopic accumulation of lipid in the liver,and is viewed as the hepatic manifestation of the metabolic syndrome.However,the molecular mechanisms mediating both the initial development of steatosis and its progression through non-alcoholic steatohepatitis to debilitating and potentially fatal fibrosis and cirrhosis are only partially understood.Despite increased research in this field,the development of non-invasive clinical diagnostic tools and the discovery of novel therapeutic targets has been frustratingly slow.We note that,to date,NAFLD research has been dominated by in vivo experiments in animal models and human clinical studies.Systems biology tools and novel computational simulation techniques allow the study of large-scale metabolic networks and the impact of their dysregulation on health.Here we review current systems biology tools and discuss the benefits to their application to the study of NAFLD.We propose that a systems approach utilising novel in silico modelling and simulation techniques is key to a more comprehensive,better targeted NAFLD research strategy.Such an approach will accelerate the progress of research and vital translation into clinic. | Ciarán P Fisher Andrzej M Kierzek Nick J Plant J Bernadette Moore | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 3 | The percutaneous absorption of lead-203 in humans from cosmetic preparations containing lead acetate, as assessed by whole-body counting and other techniques 显示文摘 | Moore M Meredith P Watson W | 1980 | Food and Cosmetics Toxicology1980，18，： | 1 |
| 4 | Invasive Pneumococcal Disease in Children 5 Years After Conjugate Vaccine Introduction - Eight States, 1998-2005显示文摘 | Reingold A Hadler J Farley M M Harrison L Lynfield R Lexau C Bennett N Thomas A Craig A S Smith P J Beall B Whitney C G Moore M Pilishvili T | 2008 | MMWR Morbidity and Mortality Weekly Report2008，，6： | 1 |
| 5 | The Lessons We (don't) Learn : Counterfactual Thinking and Organizational Accountability After a Close Call 显示文摘 | Morris M W Moore P C | 2000 | Administrative Science Quarterly2000，45，12： | 1 |
| 6 | Network formation in gluten - free bread with application of transglutaminase 显示文摘 | Moore M Heinbockel M Dockery P | 2006 | Cereal chemistry2006，83，1： | 1 |
| 7 | Effects of epidermal growth factor on hair growth in the mouse显示文摘 | Moore G P M Panaretto B A Robertson D M | 1981 | J Endocrinol1981，88，2： | 1 |
| 8 | Time-dependence of hazard ratios for prognostic factors in primary breast cancer显示文摘 | HILSENBECK S G RAVDIN P M DE MOOR C A | 1998 | Breast Cancer Res Treat1998，52，13： | 1 |
| 9 | Reinforcement learning:a survey显示文摘 | Kaelbling L P Littman M L Moore A W | 1996 | Journal of Artificial Intelligence Research1996，4，： | 1 |
| 10 | An exploration of the meaning and consequences of workaholism显示文摘 | Scott K S Moore K S Miceli M P | 1997 | Human Rela- tions1997，50，： | 1 |
| 11 | De-mand articulation in emerging technologies: intermediary user organisations as co-producers? 显示文摘 | BOON W P C MOORS E H M KUHLMANN S | 2010 | Research Policy2010，40，2： | 1 |
| 12 | Amoxicillin for acute lower- re- spiratory -tract infection in primary care when pneumonia is not sus- pected : a 12 - country, randomised, placebo - controlled trial 显示文摘 | Little P Stuart B Moore M | 2013 | Lancet Infect Dis2013，13，2： | 1 |
| 13 | Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunod- eficiency virus type 1 显示文摘 | Roben P Moore JP Thali M | 1994 | J Virol1994，68，8： | 1 |
| 14 | Mechanical properties, water vapor permeability and water affinity of feather keratin films plasticized with sorbitol显示文摘 | MARTELLI S M MOORE G R P LAURINDO J B | 2006 | Journal of Polymers and the Environment2006，14，3： | 1 |
| 15 | Inhibi tion of wool growth in Merino sheep following admin istration of mouse epidermal growth factor and a de rivative显示文摘 | Moore G P M Panaretto B A Robertson D M | 1982 | Aust J Biol Sci1982，35，2： | 1 |
| 16 | Stratospheric residence time of strontium,90 显示文摘 | Kuroda P K Hodges H L Fry L M Moore H E | 1962 | Science1962，137，3523： | 1 |
| 17 | Reliability of measurement of muscle tone and muscle power in stroke patients 显示文摘 | Gregson J Leathley M Moore P | 2000 | Age Ageing(S0002 - 0729)2000，29，： | 1 |
| 18 | Austenite stability ef- fects on tensile behavior of manganese-enriched-austenite trans- formation- induced plasticity steel显示文摘 | Gibbs P J De Moor E Merwin M J | 2011 | Metall Mater Trans A2011，42，12： | 1 |
| 19 | Expression of listeriolysin O and ActA by intracellular and extracellular Listeria monocytogenes 显示文摘 | Moors M A Levitt B Youngman P | 1999 | Infect Immun1999，67，： | 1 |
| 20 | Coupled ocean–atmosphere dynamics in the Indian Ocean during 1997–98显示文摘 | WEBSTER P J MOORE A M LOSCHNIGG J P | 1999 | Nature1999，401，6751： | 1 |
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