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| 1 | Prognostic value of increased carbohydrate antigen in patients with heart failure显示文摘AIM:To study the prognostic value of carbohydrateantigen 125(CA125) and whether it adds prognostic information to N-terminal pro-brain natriuretic peptide(NT-proBNP) in stable heart failure(HF) patients.METHODS:The predictive value of CA125 was retrospectively assessed in 156 patients with stable HF remitted to the outpatient HF unit for monitoring from 2009 to 2011.Patients were included in the study if they had a previous documented episode of HF and received HF treatment.CA125 and NT-proBNP concentrations were measured.The independent association between NT-proBNP or CA125 and mortality was assessed with Cox regression analysis,and their combined predictive ability was tested by the integrated discrimination improvement(IDI) index.RESULTS:The mean age of the 156 patients was 72 ± 12 years.During follow-up(17 ± 8 mo),27 patients died,1 received an urgent heart transplantation and 106 required hospitalization for HF.Higher CA125 values were correlated with outcomes:58 ± 85 KU/L if hospitalized vs 34 ± 61 KU/L if not(P < 0.05),and 94 ± 121 KU/L in those who died or needed urgent heart transplantation vs 45 ± 78 KU/L in survivors(P < 0.01).After adjusting for propensity scores,the highest risk was observed when both biomarkers were elevated vs not elevated(HR = 8.95,95%CI:3.11-25.73; P < 0.001) and intermediate when only NT-proBNP was elevated vs not elevated(HR = 4.15,95%CI:1.41-12.24; P < 0.01).Moreover,when CA125 was added to the clinical model with NT-proBNP,a 4%(P < 0.05) improvement in the IDI was found.CONCLUSION:CA125 > 60 KU/L identified patients in stable HF with poor survival.Circulating CA125 level adds prognostic value to NT-proBNP level in predicting HF outcomes. | Ana B Méndez Jordi Ordonez-Llanos Andreu Ferrero Mariana Noguero Teresa Mir Josefina Mora Antoni Bayes-Genis Sònia Mirabet Juan Cinca Eulàlia Roig | 2014 | World Journal of Cardiology2014，6，4： | 13 |
| 2 | A NETWORK ANALYSIS OF THE 2010 FIFA WORLD CUP CHAMPION TEAM PLAY显示文摘This paper analyzes the network of passes among the players of the Spanish team during the last FIFA World Cup 2010,where they emerged as the champion,with the objective of explaining the results obtained from the behavior at the complex network level.The team is considered a network with players as nodes and passes as(directed) edges.A temporal analysis of the resulting passes network is also done,looking at the number of passes,length of the chain of passes,and to network measures such as player centrality and clustering coefficient.Results of the last three matches(the decisive ones) indicate that the clustering coefficient of the pass network remains high,indicating the elaborate style of the Spanish team.The effectiveness of the opposing team in negating the Spanish game is reflected in the change of several network measures over time,most importantly in drops of the clustering coefficient and passing length/speed,as well as in their being able in removing the most talented players from the central positions of the network.Spain's ability to restore their combinative game and move the focus of the game to offensive positions and talented players is shown to tilt the balance in favor of the Spanish team. | COTTA Carlos MORA Antonio M MERELO Juan Julin MERELO-MOLINA Cecilia | 2013 | Journal of Systems Science & Complexity2013，26，1： | 4 |
| 3 | Rice Drying,Storage and Processing:Effects of Post-Harvest Operations on Grain Quality显示文摘Various post-harvest processes of rice are commonly employed,especially during the off-season,to ensure its consumption feasibility,which often affect the grain quality.Different forms of drying,storage and processing of rice are evaluated to identify their effects on grain quality.Microwave drying has emerged as an alternative to the widely-used intermittent-drying and fixed-bed-dryer methods of drying paddy rice.Control of drying-air temperatures(between 40℃ and 60℃)according to the rice variety can improve quality,especially for exotic varieties.Keeping stored grain in hygroscopic balance,with water content between 11%to 15%,at temperatures between 16℃ and 20℃ and with intergranular relative humidity near 60%,allows 12 months of storage in a controlled environment without significant deterioration.Other innovations,notably the application of artificial refrigeration to grain stored in bulk in vertical cylindrical silos and the use of impermeable packaging for storage,ensure the conservation of grain mass.The different stages and equipments used to obtain polished,brown and parboiled rice result in significant changes in the nutritional value of rice because of the removal of the outermost layers of the grains.Polishing reduces the nutritional value and physical homogeneity of rice.Brown rice retains more bioactive compounds and nutrients because it does not lose the outer layer of the grains in the polishing processes.Parboiled rice,although less nutritious than brown rice,has better grain integrity and milling yield and less loss of nutrients than white rice. | Amanda MÜLLER Marcela Trojahn NUNES Vanessa MALDANER Paulo Carteri CORADI Rosana Santos de MORAES Samuel MARTENS Andressa Fernandes LEAL Vladison Fogliato PEREIRA Cristielle König MARIN | 2022 | Rice science2022，29，1： | 3 |
| 4 | Fluorine-containing amorphous hydrogenated carbon films显示文摘 | Durrant S F Bica de Moraes M A | 1996 | Thin Solid Films1996，，： | 2 |
| 5 | Murine model to study brain,behavior and immunity during hepatic encephalopathy显示文摘AIM:To propose an alternative model of hepatic encephalopathy(HE) in mice,resembling the human features of the disease.METHODS:Mice received two consecutive intraperitoneal injections of thioacetamide(TAA) at low dosage(300 mg/kg).Liver injury was assessed by serum transaminase levels(ALT) and liver histology(hematoxylin and eosin).Neutrophil infiltration was estimated by confocal liver intravital microscopy.Coagulopathy was evaluated using prolonged prothrombin and partial thromboplastin time.Hemodynamic parameters were measured through tail cuff.Ammonia levels were quantified in serum and brain samples.Electroencephalography(EEG) and psychomotor activity score were performed to show brain function.Brain edema was evaluated using magnetic resonance imaging.RESULTS:Mice submitted to the TAA regime developed massive liver injury,as shown by elevation of serum ALT levels and a high degree of liver necrosis.An intense hepatic neutrophil accumulation occurred in response to TAA-induced liver injury.This led to mice mortality and weight loss,which was associated with severe coagulopathy.Furthermore,TAA-treated mice presented with increased serum and cerebral levels of ammonia,in parallel with alterations in EEG spectrum and discrete brain edema,as shown by magnetic resonance imaging.In agreement with this,neuropsychomotor abnormalities ensued 36 h after TAA,fulfilling several HE features observed in humans.In this context of liver injury and neurological dysfunction,we observed lung inflammation and alterations in blood pressure and heart rate that were indicative of multiple organ dysfunction syndrome.CONCLUSION:In summary,we describe a new murine model of hepatic encephalopathy comprising multiple features of the disease in humans,which may provide new insights for treatment. | Lindisley Ferreira Gomides Pedro Elias Marques Bruno Engler Faleiros Rafaela Vaz Pereira Sylvia Stella Amaral Thais Reis Lage Gustavo Henrique Souza Resende Patricia Alves Maia Guidine Giselle Foureaux Fabíola Mara Ribeiro Fabiana Paiva Martins Marco Antonio Peliky Fontes Anderson José Ferreira Remo Castro Russo Mauro Martins Teixeira Márcio Flávio Moraes Antonio Lúcio Teixeira Gustavo Batista Menezes | 2014 | World Journal of Hepatology2014，6，4： | 2 |
| 6 | Spectral classification of water masses under the influence of the Amazon River plume显示文摘The large amount of dissolved and particulate material discharged by the Amazon River into the Equatorial Atlantic Ocean cause distinct spectral response of its waters as compared to the nearby ocean waters. This paper shows the application of K-means clustering algorithm for classifying water masses in the region under the Amazon River plume influence according to their spectral behavior. Salinity and temperature data from 67 oceanographic stations were related to Sea-viewing Wide Field-of-view Sensor (SeaWiFS) remote sensing reflectances values and the following bio-optical products: (i) chlorophyll-a concentration, (ii) water attenuation coefficient and (iii) absorption coefficient for dissolved and detrital material. Four different water masses were identified such as: (1) oceanic water, (2) intermediate oceanic water, (3) intermediate river plume water and (4) Amazon River plume water. The spectral behavior of these water masses allowed concluding that the main active optical component of the waters in the region is the colored dissolved organic matter originated mostly from the Amazon River. | Gustavo Souto Fontes Molleri Milton Kampel Evlyn Mrcia Leo de Moraes Novo | 2010 | Acta Oceanologica Sinica2010，29，3： | 2 |
| 7 | Rheological and mechanical properties of filled rubber:silica-silicone显示文摘 | ARANGUREN M I MORA E | 1994 | Rubber Chemistry and Technology1994，67，： | 1 |
| 8 | Digestion of biological materials using the microwave-assisted sample combustion technique 显示文摘 | Mesko M F Moraes D P Barin J S Dressler V L Knapp G Flores E M M | 2006 | Microchem Journal2006，82，： | 1 |
| 9 | Resection of malignant brain tumors in eloquent cortical areas: a new multimodal approach combining 5 aminoIevulinic acid and intraoperative monitoring显示文摘 | Feigi GC Ritz R Moraes M | 2010 | J Neurosurg2010，113，2： | 1 |
| 10 | Percataneous ultra- sound-guided renal biopsy in children-safety, efficacy, indications and renal pathology findings: 14-year Brazilian university hospital experi- ence显示文摘 | Piotto G H Moraes M C Malheiros D M | 2008 | Clin Nephrol2008，69，6： | 1 |
| 11 | Schistosoma mansoni: In vitro schistosomicidal activity ofpiplartine 显示文摘 | de Moraes J Nascimento C Lopes P O M V | 2011 | Exp Parasitol2011，127，2： | 1 |
| 12 | Endotoxin-induced lung injury in mice : structural, functional, and biochemical responses显示文摘 | Rojas M Woods C R Mora A L | 2005 | Am J Physiol Lung Cell Mol Physiol2005，288，： | 1 |
| 13 | A Luenberger-observer for nonlinear systems 显示文摘 | Ciccarella G Dalla mora M Germani A | 1993 | International Journal of Control1993，57，3： | 1 |
| 14 | Characterization of my coviruses and analyses of chitinase secretion in the biocontrol fungus Metarhizium anisopliae显示文摘 | Gimenez-Pecci M de la Bogo P M R Santi L Moraes C K de Correa C T Vainstein M H Schrank A | 2002 | Current Microbiology2002，45，5： | 1 |
| 15 | Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma显示文摘 | Alaminos M Mora J Cheung NK Smith A Qin J Chen L Gerald WL | 2003 | Cancer Res2003，63，8： | 1 |
| 16 | Theoretical calculation for a two-axis magnetometer based on magnetization rotation显示文摘 | GARCIA A MORN C MORA M | 2000 | Sen- sors and Actuators A: Physical2000，81，13： | 1 |
| 17 | An adenovirus vectored mucosal adjuvant augments protection of mice immunized in- tranasally with an adenovirus-vectored foot-and-mouth disease vi- rus subunit vaccine显示文摘 | Alejo D M Moraes M P Liao X | 2013 | Vaccine2013，31，18： | 1 |
| 18 | Podophyllotoxin 显示文摘 | Canel C Moraes R M Frank E D | 2000 | Phytochem2000，54，2： | 1 |
| 19 | Mucocele of the gland of Blandin-Nuhn: Histological and clinical findings显示文摘 | De Camargo Moraes P Bonecker M Furuse C | 2009 | Clin Oral Investig2009，13，3： | 1 |
| 20 | Quebrachitolattenuates 6-Hydroxydopamine-Induced Cytotoxicity in Ratfetal Mesencephalic Cell Cultures显示文摘 | Nobre H V Cunba G M A Moraes M O | 2006 | Food Cheml Toxicol2006，44，： | 1 |
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