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171篇 您的检索式:作者名="Naing CM"
    题名 作者 年代 出处 被引量
1Association of telomere length with authentic pluripotency of ES/iPS cells显示文摘Telomerase 和 telomeres 为干细胞的不定的复制是重要的。最近,体的房间的 telomeres 被发现是 reprogrammed 在导致的 pluripotent 干细胞(iPSCs ) 伸长。然而,在在胚胎的干细胞(转换字符) 或 iPSCs 的 vivo 的发展 pluripotency 的 telomeres 的角色直接没被探讨。我们证明有长 telomeres 的转换字符展出真发展 pluripotency,由完全的转换字符小狗以及 germline 能干的怪物的产生证实了在啮齿类动物可得到的最紧的测试。有短 telomeres 的转换字符显示出减少的 teratoma 形成和怪物生产,并且没能产生完全的转换字符小狗。Telomere 长度高度被相关(r > 0.8 ) 与转换字符的发展 pluripotency。短 telomeres 减少 proliferative 率或转换字符的能力,改变与 telomere epigenetics 有关的基因的表示,为 embryogenesis 重要的下面调整基因并且破坏细菌房间区别。而且,有更长的 telomeres 的 iPSCs 与短 telomeres 比那些与更高的效率产生怪物。我们功能的 telomeres 为 ESCs/iPSCs 的发展 pluripotency 是必要的并且建议那 telomere 长度可以提供一个珍贵标记评估干细胞 pluripotency 的数据表演,特别地当紧测试不是可行的时。Junjiu Huang Fang Wang Maja Okuka Na Liu Guangzhen Ji Xiaoying Ye Bingfeng Zuo Minshu Li Ping Liang William W Ge John CM Tsibris David L Keefe Lin Liu 2011Cell Research2011,21,5:3
2遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人,刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM 2017中华高血压杂志2017,25,2:2
3Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors 显示文摘Lokker NA Sullivan CM Hollenbach S J 2002Cancer Res2002,62,13:1
4Dilated intercelhilar spaces as a marker of oesophageal damage:comparative results in gastroesophageal reflux disease with or without bile reflux显示文摘Tobey NA Hosseini SS Argote CM 2003Aliment Pharmacol Ther2003,18,:1
5The role of P selectin and ICAM-1 in acute lung injury as determined using blocking antibodies and mutant mice显示文摘Doerschuk CM Quinlan WM Doyle NA 1996J Immu- nol1996,157,10:1
6Surgical management for rectal prolapse: an update显示文摘Murphy PB Schlachta CM Alkhamesi NA 2015Minerva Chir2015,70,4:1
7Pulse pressure in normotensives: a make of cardiovarscular disease 显示文摘Zakopoulos NA Lekakis JP Papamichael CM 2011Am J Hypertens2011,14,3:1
8Regulation of erythropoietin gene expression depends on two different oxygen-sensing mechanisms 显示文摘Daghman NA Mchale CM Savage GM 1996Mol Genet Metab1996,67,2:1
9Regulation of Toll like receptor (TLR) 2 and TLR4 on CD14 + dim CD16 + monocytes in response to sepsis related antigens 显示文摘Skinner NA Maclsaac CM Hamilton JA 2005Clin Exp Immunol2005,141,2:1
10Pulse pressure in norrnotensives :a marker of cardiovascular disease显示文摘Zakopoulos NA Lekakis JP Papamichael CM 2001Am J Hypertens2001,14,3:1
11Pulse pressure in nomotensives: a marker of cardiovascular disease 显示文摘Zakopoulos NA Lekakis JP Papamichael CM 2001Am J Hypertens2001,14,3:1
12Pulse pressure in normotensives: a marker of cardiovascular disease 显示文摘Zakopoulos NA Lekakis JP Papamichael CM 2001Am J Hypemens2001,14,3:1
13Assessment of nuclear and cytoplasmic maturation in IVM MI human oocytes显示文摘Combelles CM Cekleniak NA Racowsky C 2002Hum Reprod2002,17,4:1
14Pulse pressure in normotensives:A marker of Cardiovascular disease显示文摘Zakopoulos NA Lekakis TP Papamichael CM 200114:195~ 1992001,14,:1
15Pulse pressure in normotensives:a maeker of cardiovascular disease 显示文摘Zakopoulos NA Lekakis JP Papamicchael CM 2001American Journal of Hypertension2001,14,3:1
16Pulse pressure in normotensive: a marker of cardiovascular disease显示文摘Zakopoulos NA Lekakis JP Papmichael CM 2001Am J Hypertension2001,14,:1
17Pulse pressure in normotensives:a marker of cardiovascular disease显示文摘 Lekakis JP Papamichael CM 2001Am J Hypertens2001,14,30:1
18A novel system for in vitro maturation of human oocytes 显示文摘CEKLENIAK NA COMBELLES CM GANZ DA 2001Fertil Steril2001,75,:1
19Randomized phase II trial of gemcitabine plus irinotecan or docetaxel in stage IIIB or stage IV NSCLC显示文摘Rocha Lima CM Rizvi NA Zhang C 2004Ann Oncol2004,15,3:1
20Pulse pressure in normotensives:a marker of cardiovascular disease显示文摘Zakopouls NA Lekakis JP Papamichael CM 2001Am J Hypertens2001,14,3:1
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