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| 1 | Ileal pouch surgery for ulcerative colitis显示文摘Ulcerative colitis (UC) is a relapsing and remitting disease characterised by chronic mucosal and submucosal inflammation of the colon and rectum. Treatment may vary depending upon the extent and severity of inflammation. Broadly speaking medical treatments aim to induce and then maintain remission. Surgery is indicated for inflammatory disease that is refractory to medical treatment or in cases of neoplastic transformation. Approximately 25% of patients with UC ultimately require colectomy. Ileal pouch-anal anastomosis (IPAA) has become the standard of care for patients with ulcerative colitis who ultimately require colectomy. This review will examine indications for IPAA, patient selection, technical aspects of surgery, management of complications and long term outcome following this procedure. | Simon P Bach Neil J Mortensen | 2007 | World Journal of Gastroenterology2007，13，24： | 10 |
| 2 | Transanal total mesorectal excision:a valid option for rectal cancer?显示文摘Low anterior resection can be a challenging operation, especially in obese male patients and in particular after radiotherapy. Transanal total mesorectal excision(Ta TME) might offer technical advantages over laparoscopic or open approaches particularly for tumors in the distal third of the rectum. The aim of this article is to review the current experience with Ta TME. The limits and future developments are also explored. Although the experience with Ta TME is still limited, it might be a promising alternative to laparoscopic TME, especially for difficult cases where laparoscopy is too demanding. The preliminary data on complications and short-term oncological outcomes are good, but also emphasize the importance of careful patient selection. Finally, there is a need for large-scale trials focusing on long-term outcomes and oncological safety before widespread adoption can be recommended. | Nicolas C Buchs Gary A Nicholson Frederic Ris Neil J Mortensen Roel Hompes | 2015 | World Journal of Gastroenterology2015，21，41： | 3 |
| 3 | Botulinum Toxin as Second-Line Therapy for Chronic Anal Fissure Failing 0.2 Percent Glyceryl Trinitrate显示文摘 | Ian Lindsey F.R.A.C.S. Oliver M. Jones F.R.C.S. Chris Cunningham M.D. F.R.C.S. Bruce D. George M.S. F.R.C.S. Neil J. M. Mortensen M.D. F.R.C.S | 2003 | Diseases of the Colon & Rectum2003，，3： | 2 |
| 4 | Comparative outcomes of rectal cancer surgery between elderly and non-elderly patients: a systematic review显示文摘 | Gilles Manceau Mehdi Karoui Andrew Werner Neil J Mortensen Laurent Hannoun | 2012 | Lancet Oncology2012，，12： | 2 |
| 5 | The pattern and outcome of acute severe colitis显示文摘 | Lotte C. Dinesen Alissa J. Walsh Marijana Nedeljkovic Protic Graham Heap Fraser Cummings Bryan F. Warren Bruce George Neil J.M. Mortensen Simon P.L. Travis | 2010 | Journal of Crohn’s and Colitis2010，，： | 1 |
| 6 | Impotence after mesorectal and close rectal dissection for inflammatory bowel disease显示文摘 | Ian Lindsey Bruce D. George Mike G. W. Kettlewell Neil J. Mc. C. Mortensen | 2001 | Diseases of the Colon & Rectum2001，，： | 1 |
| 7 | Randomized, Double-Blind, Placebo-Controlled Trial of Sildenafil (Viagra?) for Erectile Dysfunction After Rectal Excision for Cancer and Inflammatory Bowel Disease显示文摘 | Ian Lindsey Bruce George Michael Kettlewell Neil Mortensen | 2002 | Diseases of the Colon & Rectum2002，，： | 1 |
| 8 | Near-infrared (NIR) perfusion angiography in minimally invasive colorectal surgery显示文摘 | Frederic Ris Roel Hompes Chris Cunningham Ian Lindsey Richard Guy Oliver Jones Bruce George Ronan A. Cahill Neil J. Mortensen | 2014 | Surgical Endoscopy2014，，7： | 1 |
| 9 | Comparative outcomes of rectal cancer surgery between elderly and non-elderly patients: a systematic review显示文摘 | Gilles Manceau Mehdi Karoui Andrew Werner Neil J Mortensen Laurent Hannoun | 2012 | Lancet Oncology2012，，12： | 1 |
| 10 | Persistent pain and faecal urgency after stapled haemorrhoidectomy显示文摘 | Mark J Cheetham Neil JM Mortensen Per-Olof Nystrom Michael A Kamm Robin KS Phillips | 2000 | The Lancet2000，，9231： | 1 |
| 11 | Recurrence After Abdominal Surgery for Crohn?s Disease: Relationship to Disease Site and Surgical Procedure显示文摘 | Neil R. Borley Neil J. McC. Mortensen Mohammed A. Chaudry Said Mohammed Bryan F. Warren Bruce D. George Taane Clark Derek P. Jewell Michael G. W. Kettlewell | 2002 | Diseases of the Colon & Rectum2002，，3： | 1 |
| 12 | Comparative outcomes of rectal cancer surgery between elderly and non-elderly patients: a systematic review显示文摘 | Gilles Manceau Mehdi Karoui Andrew Werner Neil J Mortensen Laurent Hannoun | 2012 | Lancet Oncology2012，，12： | 1 |
| 13 | Fistulating Anal Crohn’s Disease: Results of Combined Surgical and Infliximab Treatment显示文摘 | Syed A. Hyder Simon P. L. Travis Derek P. Jewell Neil J. Mortensen Bruce D. George | 2006 | Diseases of the Colon & Rectum2006，，12： | 1 |
| 14 | Waist Circumference and Waist/Hip Ratio Are Better Predictive Risk Factors for Mortality and Morbidity after Colorectal Surgery Than Body Mass Index and Body Surface Area显示文摘 | Alex H. Kartheuser Daniel F. Leonard Freddy Penninckx Hugh M. Paterson Dimitri Brandt Christophe Remue Céline Bugli Eric Dozois Neil Mortensen Frédéric Ris Emmanuel Tiret | 2013 | Annals of Surgery2013，，5： | 1 |
| 15 | Denonvilliers’ Fascia Lies Anterior to the Fascia Propria and Rectal Dissection Plane in Total Mesorectal Excision显示文摘 | Ian Lindsey M.B.B.S. F.R.A.C.S. Bryan F. Warren F.R.C.P. Neil J. Mortensen M.D. F.R.C.S | 2005 | Diseases of the Colon & Rectum2005，，1： | 1 |
| 16 | Natural orifice transluminal endoscopic surgery and localized resection for colorectal neoplasia显示文摘Modern methods of surgical intervention have the potential to provide effective,definitive management of early stage colorectal neoplasia by truly minimally invasive means.Margin-free clearance of early colonic neoplasia from within the intestinal lumen can already now be effected by endoscopic submucosal dissection in the colon and transluminal endoscopic microsurgery(TEM) in the rectum.Natural orifice transluminal endoscopic surgery(NOTES) offers the potential for providing transmural,full thickness excision as TEM does but at sites in the colon proximal to the rectum.The next conceptual advance required to make this practice an effective reality lies in evolving surgical regional staging strategies to effectively partner localized resective approaches and allow their deployment as definitive curative therapy.As the most compelling modality for nodal status ascertainment in the absence of lymphatic basin excision for other malignant disease processes,it seems timely to reconsider sentinel node biopsy in cancer of the colon and rectum.Whether by this means or indeed any other,such an ability to confidently identify patients with node negative disease would allow nascent innovative techniques flourish as definitive management for confined(N0) T1 and T2 cancers and so allow the application of available advanced technology for clinical benefit.Conversely,the development of a specific clinical niche for NOTES(whether,as here,for full thickness localized colonic excision or nodal staging alone) would greatly benefit the evolution and incorporation of this surgical strategy into clinical care paradigms. | Ronan A Cahill Neil J Mortensen | 2010 | World Journal of Gastrointestinal Surgery2010，2，6： | 1 |
| 17 | Patterns of Fecal Incontinence After Anal Surgery显示文摘 | Ian Lindsey M.B.B.S. F.R.A.C.S. Oliver M. Jones F.R.C.S. M. M. Smilgin-Humphreys R.N. Chris Cunningham M.D. F.R.C.S. Neil J. Mortensen M.D. F.R.C.S | 2004 | Diseases of the Colon & Rectum2004，，10： | 1 |
| 18 | IBD care in Europe: A comparative audit of the inpatient management of Crohn’s disease and ulcerative colitis using the national UK IBD audit tool显示文摘 | Andrea Cassinotti Satish Keshav Sandro Ardizzone Neil Mortensen Gianluca Sampietro Paolo Fociani Piergiorgio Duca Bruce George Marco Lazzaroni Gianpiero Manes Brian Warren Diego Foschi Gianluca Vago Gabriele Bianchi Porro Simon Travis | 2009 | Journal of Crohn’s and Colitis2009，，： | 1 |
| 19 | Persistent pain and faecal urgency after stapled haemorrhoidectomy显示文摘 | Mark J Cheetham Neil JM Mortensen Per-Olof Nystrom Michael A Kamm Robin KS Phillips | 2000 | 2000 (9231)2000，，9231： | 1 |
| 20 | Natural history of uncomplicated sigmoid diverticulitis显示文摘While diverticular disease is extremely common, the natural history(NH) of its most frequent presentation(i.e., sigmoid diverticulitis) is poorly investigated. Relevant information is mostly restricted to populationbased or retrospective studies. This comprehensive review aimed to evaluate the NH of simple sigmoid diverticulitis. While there is a clear lack of uniformity in terminology, which results in difficulties interpreting and comparing findings between studies, this review demonstrates the benign nature of simple sigmoid diverticulitis. The overall recurrence rate is relatively low, ranging from 13% to 47%, depending on the definition used by the authors. Among different risk factors for recurrence, patients with C-reactive protein > 240 mg/L are three times more likely to recur. Other risk factors include: Young age, a history of several episodes of acute diverticulitis, medical vs surgical management, male patients, radiological signs of complicated first episode, higher comorbidity index, family history of diverticulitis, and length of involved colon > 5 cm. The risk of developing a complicated second episode(and its corollary to require an emergency operation) is less than 2%-5%. In fact, the old rationale for elective surgery as a preventive treatment, based mainly on concerns that recurrence would result in a progressively increased risk of sepsis or the need for a colostomy, is not upheld by the current evidence. | Nicolas C Buchs Neil J Mortensen Frederic Ris Philippe Morel Pascal Gervaz | 2015 | World Journal of Gastrointestinal Surgery2015，7，11： | 0 |
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