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| 1 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 2 | A comparison of a dispos-able skin stapler and nylon sutures for wound closure显示文摘 | Meiring L Cilliers K Barry R Nel CJ | | 0，，： | 1 |
| 3 | The personal and general hygiene practices in the deboning room of a high throughput red meat abattoir显示文摘 | Nel S Lues J F R Buys E M | 2004 | Food Control2004，15，： | 1 |
| 4 | Impact of allogeneic haematopoietic stem cell transplantation in patients with abnl(17p) acute myeloid leukaemia显示文摘 | Brigitte Mohr Johannes Schetelig Kerstin Sch?fer‐Eckart Norbert Schmitz Mathias H?nel Wolf R?sler Norbert Frickhofen Hartmut Link Andreas Neubauer Ulrich Schuler Uwe Platzbecker Jan M. Middeke Gerhard Ehninger Martin Bornh?user Markus Schaich Friedrich St | 2013 | Br J Haematol2013，，： | 1 |
| 5 | Effects of solution properties on solute and permeate flux in bovine serum albumin-IgG ultrafiltration显示文摘 | Nel R G Oppenheim S F Rodgers V G J | 1994 | Biotechnol Prog1994，10，： | 1 |
| 6 | Family history of malignant and benign thyroid diseases and risk of thyroid cancer: a population-based case–control study in New Caledonia显示文摘 | Christophe Leux Thérèse Truong Claire Petit Dominique Baron-Dubourdieu Pascal Guénel | 2012 | Cancer Causes & Control2012，，5： | 1 |
| 7 | Drug induced arousal from the permanent vegetative state 显示文摘 | Clauss R Nel W | 2006 | Neurorehabilitation2006，21，1： | 1 |
| 8 | Visual and nonvisual variables implicated in monovision wear显示文摘 | du Toit R Ferreira JT Nel ZJ | 1998 | Optom Vis Sci1998，75，2： | 1 |
| 9 | Bacterial populations associated with meat from the deboning room of a high throughput red meat abattoir 显示文摘 | NEL S LUESA J F R BUYS E M | 2004 | Meat Science2004，66，3： | 1 |
| 10 | Low serum testosterone and increased diastolic ocular perfusion pressure:a risk for retinal microvasculature显示文摘 | Malan NT Smith W von Knel R | 2015 | Vasa2015，44，6： | 1 |
| 11 | Public-health impact of outdoor and traffic-related air pollution: a European assessment显示文摘 | N Künzli R Kaiser S Medina M Studnicka O Chanel P Filliger M Herry F Horak V Puybonnieux-Texier P Quénel J Schneider R Seethaler J-C Vergnaud H Sommer | 2000 | The Lancet2000，，9232： | 1 |
| 12 | Growth optimization of Pediococcus damnosus NCFB 1832 and the influence of pH and nutrients on the production of pediocin PD-1 显示文摘 | NEL H A BAUER R VANDAMME E J | 2001 | Applied Microbiology2001，91，6： | 1 |
| 13 | Growth opti- mization of Pediococcus damnosus NCFB1832 and the influence of pH and nutrients on the production of pediocin PD-1显示文摘 | NEL H A BAUER R VANDAMME E J | 2001 | Ap- plied Microbiology2001，91，6： | 1 |
| 14 | Stress hormones in patients with posttraumatic stress disorder caused by myocardial infarction and role of comorbid depression显示文摘 | von K(a)nel R Schmid JP Abbas CC | | 0，，01： | 1 |
| 15 | Characterization of major histocompatibility complex DRB diversity in the endemic South African antelope Damaliscus pygargus: A comparison in two subspecies with different demographic histories显示文摘 | van der Walt J M Nel L H Hoelzel A R | 2001 | Molecular Ecology2001，10，7： | 1 |
| 16 | Clinical evaluation of the Nucleus? 6 cochlear implant system: Performance improvements with SmartSound iQ显示文摘 | Stefan J Mauger Chris D Warren Michelle R Knight Michael Goorevich Esti Nel | 2014 | International Journal of Audiology2014，，8： | 1 |
| 17 | Visual and nonvisual variables implicated in monovision wear 显示文摘 | du Toil R Ferreira JT Nel ZJ | 1998 | Optom Vis Sci1998，75，2： | 1 |
| 18 | The closure of coal mines and local development responses in Coal-Rim Cluster, Northern KwaZulu-Natal, South Africa显示文摘 | NEL ETIENNE L TREVOR R H | 2003 | Development Southern Africa2003，20，3： | 1 |
| 19 | Reservoir properties of the Upper Creta-ceous Lewis Shale,a new natural gas play in the San J uan Basin显示文摘 | Hill D G Nel son C R | 2000 | AAPG Bulletin2000，84，8： | 1 |
| 20 | Induction of attachment-independent biof ilm formation and repression of Hfq expression by low-f luid-shear cult ure of staphylococcus aureus显示文摘 | C st ro SL Nel m a n-Gon z alez M Nicke r son CA | 2011 | Appl Environ Microbiol2011，77，18： | 1 |
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