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413篇 您的检索式:作者名="Nichol A M"
    题名 作者 年代 出处 被引量
1Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly 2012Cellular & Molecular Immunology2012,9,3:3
2The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Trial显示文摘E Feldmann J L. Wilterdink A Kosinski M Lynn M I. Chimowitz J Sarafin H H. Smith F Nichols J Rogg H J. Cloft L Wechsler J Saver S R. Levine C Tegeler R Adams M Sloan 2007Neurology2007,,24:2
3Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb 显示文摘Li Yan Nichols M A Shay J W 1994Cancer Res1994,54,23:1
4Intrauterine lidocaine infusion for pain management in first-trimester abortions显示文摘EDELMAN A NICHOLS M D LECLAIR C 2004Obstet Gynecol2004,103,6:1
5查看详情显示文摘Renoncourt A Bauduin P Nicholl E Touraud D Verbavatz J.M Dubois M Drechsler M Kunz W 0,,:1
6B-type natriuretic peptides and ejection fraction for prognosis after myocardial infarction显示文摘Richards A M Nicholls M G Espiner E A 2003Circulation2003,107,22:1
7Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions显示文摘EDELMAN A NICHOLS M D LECLAIR C 2006Obstet Gynecol2006,107,21:1
8B-type natriuretic peptides and ejection fraction for prognosis after myovardial infraction 显示文摘Richards A M Nicholls M G Espiner E A 2003Circulation2003,107,22:1
9Haemorrhoids: pathology, pathophysiology and aetiology显示文摘Loder P B Kamm M A Nicholls R J 1994Br J Surg1994,81,7:1
10Pharmacokinetics of mycophenolate Mofetil(RS61443):a short review显示文摘Bullinghan RES Nicholls A Hale M 1996Transplant Proc1996,28,2:1
11Restored immune response to an MHC-II-Restrieted antigen in tumor-bearing hosts after elimination of regulatory T eells显示文摘Nicholl M Lodge A Brown I 2004J Pediatr Surg2004,39,6:1
12Growth effects of systemic versus inhaled steroids in chronic lung disease显示文摘Nicholl RM Greenough A King M 2002Arch Dis Child Fetal Neonatal Ed2002,87,1:1
13A Rac homolog functions downstream of Rasl to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformans显示文摘Vallim M A Nichols C B Fernandes L 2005Eukaryotic Cell2005,4,6:1
14ATPase and multidrug transportactivities of the overexpressed yeast ABC protein Yor1p 显示文摘Decottignies A Grant A M Nichols J W 1994J Biol Chem1994,269,12:1
15Dynamic lactate indices as predictors of outcome in critically ill patients显示文摘Nichol A Bailey M Egi M 2011Crit Care2011,15,5:1
16The incidence of deep venous thrombosis after laparoscopic holecystectomy 显示文摘Patel M T Hardman D T A Nicholls D 2001MJA2001,164,11:1
17Incidence of cryptosporidiosis species in paediatric patients in Malawi显示文摘MORSE T D NICHOLS R A GRIMASON A M 2007Epidemiology and Infection2007,135,:1
18An etficient new algorithm for 2D line clipping:its development and analysis显示文摘Nicholl T M Lee D T Nicholl R A 1987Computer Graphics1987,21,4:1
19Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis显示文摘Zhou H M Nichols A Meda P 2000EMBO J2000,19,17:1
20Review of the lubrication of metallic surfaces by zinc dialkyldithiophosphates显示文摘M A Nicholls T Do P R Norton 2004Tribology International2004,38,1:1
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