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| 1 | Durability of Radiofrequency Ablation in Barrett’s Esophagus With Dysplasia显示文摘 | Nicholas J. Shaheen Bergein F. Overholt Richard E. Sampliner Herbert C. Wolfsen Kenneth K. Wang David E. Fleischer Virender K. Sharma Glenn M. Eisen M. Brian Fennerty John G. Hunter Mary P. Bronner John R. Goldblum Ana E. Bennett Hiroshi Mashimo Richard I | 2011 | Gastroenterology2011，，2： | 3 |
| 2 | Colonoscopy quality with Entonox? vs intravenous conscious sedation:18608 colonoscopy retrospective study显示文摘AIM To compare colonoscopy quality with nitrous oxide gas(Entonox?) against intravenous conscious sedation using midazolam plus opioid.METHODS A retrospective analysis was performed on a prospectively held database of 18608 colonoscopies carried out in Lothian health board hospitals between July 2013 and January 2016.The quality of colonoscopies performed with Entonox was compared to intravenous conscious sedation(abbreviated in this article as IVM).Furthermore,the quality of colonoscopies performed with an unmedicated group was compared to IVM.The study used the following key markers of colonoscopy quality:(1) patient comfort scores;(2) caecal intubation rates(CIRs); and (3) polyp detection rates (PDRs).We used binary logistic regression to model the data.RESULTS There was no difference in the rate of moderate-toextreme discomfort between the Entonox and IVM groups (17.9% vs 18.8%; OR = 1.06,95%CI: 0.95-1.18,P = 0.27).Patients in the unmedicated group were less likely to experience moderate-to-extreme discomfort than those in the IVM group(11.4% vs 18.8%; OR = 0.71,95%CI: 0.60-0.83,P < 0.001).There was no difference in caecal intubation between the Entonox and IVM groups(94.4% vs 93.7%; OR = 1.08,95%CI: 0.92-1.28,P = 0.34).There was no difference in caecal intubation between the unmedicated and IVM groups (94.2% vs 93.7%; OR = 0.98,95%CI: 0.79-1.22,P = 0.87).Polyp detection in the Entonox group was not different from IVM group (35.0% vs 33.1%; OR = 1.01,95%CI: 0.93-1.10,P = 0.79).Polyp detection in the unmedicated group was not significantly different from the IVM group (37.4% vs 33.1%; OR = 0.97,95%CI: 0.87-1.08,P = 0.60).CONCLUSION The use of Entonox was not associated with lower colonoscopy quality when compared to intravenous conscious sedation using midazolam plus opioid. | Alexander R Robertson Nicholas A Kennedy James A Robertson Nicholas I Church Colin L Noble | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 3 |
| 3 | Comparison of Two Dose-response Relationship of Noise Exposure Evaluation Results with High Frequency Hearing Loss显示文摘Background: Complex noise and its relation to hearing loss are difficult to measure and evaluate. In complex noise measurement, individual exposure results may not accurately represent lifetime noise exposure. Thus, the mean LAcq.8h values of individuals in the same workgroup were also used to represent LAcq.8h in our study. Our study aimed to explore whether the mean exposure levels of workers in the same workgroup represented real noise exposure better than individual exposure levels did. Methods: A cross-sectional study was conducted to establish a model for cumulative noise exposure (CNE) and hearing loss in 205 occupational noise-exposed workers who were recruited from two large automobile manufacturers in China. We used a personal noise dosimeter and a questionnaire to determine the workers' occupational noise exposure levels and exposure times, respectively. A qualified audiologist used standardized audiometric procedures to assess hearing acuity after at least 16 h of noise avoidance. Results: We observed that 88.3% of workers were exposed to more than 85 dB(A) of occupational noise (mean: 89.3 ± 4.2 dB(A)). The personal CNE (CNEp) and workgroup CNE (CNEg) were 100.5 ± 4.7 dB(A) and 100.5 ± 2.9 dB(A), respectively. In the binary logistic regression analysis, we established a regression model with high-frequency hearing loss as the dependent variable and CNE as the independent variable. The Wald value was 5.014 with CNEp as the independent variable and 8.653 with CNEg as the independent variable. Furthermore, we found that the figure for CNEg was more similar to the stationary noise reference than CNEp was. The CNEg model was better than the CNEp model. In this circumstance, we can measure some subjects instead of the whole workgroup and save manpower. Conclusions: In a complex noise environment, the measurements of average noise exposure level of the workgroup can improve the accuracy and save manpower. | Hua Zhang Nan Li Qiu-Ling Yang Wei Qiu Liang-Liang Zhu Li-Yuan Tao Robert I Davis Nicholas Heyer Yi-Ming Zhao | 2015 | Chinese Medical Journal2015，，6： | 3 |
| 4 | Metasurface-based multi-harmonic freeelectron light source显示文摘Metasurfaces are subwavelength spatial variations in geometry and material where the structures are of negligible thickness compared to the wavelength of light and are optimized for far-field applications,such as controlling the wavefronts of electromagnetic waves.Here,we investigate the potential of the metasurface near-field profile,generated by an incident few-cycle pulse laser,to facilitate the generation of high-frequency light from free electrons.In particular,the metasurface near-field contains higher-order spatial harmonics that can be leveraged to generate multiple higher-harmonic X-ray frequency peaks.We show that the X-ray spectral profile can be arbitrarily shaped by controlling the metasurface geometry,the electron energy,and the incidence angle of the laser input.Using ab initio simulations,we predict bright and monoenergetic X-rays,achieving energies of 30 keV(with harmonics spaced by 3 keV)from 5-MeV electrons using 3.4-eV plasmon polaritons on a metasurface with a period of 85 nm.As an example,we present the design of a four-color X-ray source,a potential candidate for tabletop multicolor hard X-ray spectroscopy.Our developments could help pave the way for compact multi-harmonic sources of high-energy photons,which have potential applications in industry,medicine,and the fundamental sciences. | Gilles Rosolen Liang Jie Wong Nicholas Rivera Bjorn Maes Marin Soljačić Ido Kaminer | 2018 | Light(Science & Applications)2018，7，1： | 2 |
| 5 | Phase Ⅱ, Randomized, Double - Blind, Placebo - Controlled study of recombinant human intestinal trefoil factor oral spray for prevention of oral mucositis in patients with color- ectal cancer who are receiving fluoroutacil - based chemo- therapy显示文摘 | DOUGLAS E P NICHOLAS P B LILIA I A | 2009 | J Clin Oncol2009，27，： | 1 |
| 6 | Dysfunctional mitochondria contain endogenous high-affinity human Toll like receptor 4 (TLR4) ligands and induce TLR4 mediated in flammatory reactions 显示文摘 | Nicholas SA Coughlan K Yasinska I | 2011 | Int J Bioehem Cell Biol2011，43，4： | 1 |
| 7 | Researchers' e-journal use and information seeking behavior显示文摘 | Nicholas D Williams P Rowlands I Jamali H R | 2010 | Journal of Information Science2010，，36： | 1 |
| 8 | The Attitudes and Behaviours of Illegal Downloaders显示文摘 | Williams P Nicholas D Rowlands I | 2010 | Aslib Proceedings2010，62，3： | 1 |
| 9 | Student digital information-seeking behavior in context显示文摘 | Nicholas D Huntington P Jamali H R Rowlands I Fieldhouse M | 2009 | Journal of Documentation2009，65，1： | 1 |
| 10 | Biosynthesis of Vitamin B2 显示文摘 | Boris I Wolfgang E Nicholas S | 2005 | J Biol Chem2005，31，28： | 1 |
| 11 | Follistatin complexes myostatin and antagonises myostatin-mediated inhibition of myogenesis显示文摘 | Amthor H Nicholas G Mckinnell I | 2004 | DevBiol2004，270，1： | 1 |
| 12 | An Environmental Do- main Classification of Canada Using Earth Observation Data for Biodiversity Assessment显示文摘 | Nicholas C C Michael A W Donald I | 2009 | Ecological Informatics2009，4，： | 1 |
| 13 | Google generation II: Web behavior experiments with the BBC 显示文摘 | Nicholas D Rowlands I Clark D | 2011 | Aslib Proceedings2011，63，1： | 1 |
| 14 | Scholarly communication in the digital environment: the 2005 survey of journal author behaviour and attitudes显示文摘 | Rowlands I Nicholas D | 2005 | Aslib Proceedings2005，57，6： | 1 |
| 15 | Stochastic-constraints Method in Nonstationary Hot-clutter Cancellation-Part II:Unsupervised Training Applications显示文摘 | Yuri I A Nicholas K S Stuart J A | 2000 | IEEE Trans on Aerospace and Electronic Systems2000，36，1： | 1 |
| 16 | Observer bias and sub-sampling efficiencies for estimating the number of migrating fish in rivers using dual-frequency identification sonar(DIDSON)显示文摘 | Pertremana I C Nicholas E J Scott W M | 2014 | Fisheries Research2014，，155： | 1 |
| 17 | The missing link:journal usage metrics 显示文摘 | Rowlands I Nicholas D | 2007 | Aslib Proceedings2007，59，3： | 1 |
| 18 | Frequency and stress ratio effects in high cycle fatigue of Ti-6Al-4V显示文摘 | MORRISSEY R J MCDOWELL D I NICHOLAS T | 1999 | International Journal of Fatigue1999，21，7： | 1 |
| 19 | Directions in the immune targeting of cancer: lessons learned from the cancer-testis Ag NY-ESO-1 显示文摘 | Nicholaou T Ebert L Davis I D | 2006 | Immunol Cell Biol2006，84，3： | 1 |
| 20 | Holocene periodicity in North Atlantic climate and deep-ocean flow south of Iceland显示文摘 | Giancarlo G B Nicholas M I | 1999 | Nature1999，397，6719： | 1 |
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