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| 1 | Coronary artery calcium score on low-dose computed tomography for lung cancer screening显示文摘AIM: To evaluate the feasibility of coronary artery calcium score(CACS) on low-dose non-gated chest CT(ngCCT).METHODS: Sixty consecutive individuals(30 males; 73 ± 7 years) scheduled for risk stratification by means of unenhanced ECG-triggered cardiac computed to-mography(gCCT) underwent additional unenhanced ngCCT. All CT scans were performed on a 64-slice CT scanner(Somatom Sensation 64 Cardiac, Siemens, Germany). CACS was calculated using conventional methods/scores(Volume, Mass, Agatston) as previ-ously described in literature. The CACS value obtained were compared. The Mayo Clinic classification was used to stratify cardiovascular risk based on Agatston CACS. Differences and correlations between the two methods were compared. A P-value < 0.05 was considered sig-nificant.RESULTS: Mean CACS values were significantly higher for gCCT as compared to ngCCT(Volume: 418 ± 747 vs 332 ± 597; Mass: 89 ± 151 vs 78 ± 141; Agatston: 481 ± 854 vs 428 ± 776; P < 0.05). The correlation between the two values was always very high(Volume: r = 0.95; Mass: r = 0.97; Agatston: r = 0.98). Of the 6 patients with 0 Agatston score on gCCT, 2(33%) showed an Agatston score > 0 in the ngCCT. Of the 3 patients with 1-10 Agatston score on gCCT, 1(33%) showed an Agatston score of 0 in the ngCCT. Overall, 23(38%) patients were reclassified in a different car-diovascular risk category, mostly(18/23; 78%) shifting to a lower risk in the ngCCT. The estimated radiation dose was significantly higher for gCCT(DLP 115.8 ± 50.7 vs 83.8 ± 16.3; Effective dose 1.6 ± 0.7 mSv vs 1.2 ± 0.2 mSv; P < 0.01).CONCLUSION: CACS assessment is feasible on ngCCT; the variability of CACS values and the associated re-stratification of patients in cardiovascular risk groups should be taken into account. | Teresa Arcadi Erica Maffei Nicola Sverzellati Cesare Mantini Andrea I Guaricci Carlo Tedeschi Chiara Martini Ludovico La Grutta Filippo Cademartiri | 2014 | World Journal of Radiology2014，6，6： | 4 |
| 2 | Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients显示文摘 | Antonio Facciorusso Valentina Del Prete Nicola Crucinio Nicola Muscatiello Brian I Carr Alfredo Di Leo Michele Barone | 2015 | J Gastroenterol Hepatol2015，，11： | 2 |
| 3 | Ciliated hepatic foregut cyst:an increasingly diagnosed condition显示文摘BACKGROUND:Ciliated foregut cysts of the liver are rare, with only 96 cases diagnosed since the first description in 1857.They are being increasingly diagnosed recently;the majority of the cases have been reported in the last 15 years. Although they bear a close resemblance to the simple cyst of the liver which has essentially a benign course,ciliated hepatic foregut cysts(CHFCs)can progress to malignancy with devastating consequences.It is imperative that this group of conditions be diagnosed and treated adequately. DATA SOURCES:This review includes discussion of the data from all the 96 reported cases from English and non-English literature.Analysis of the incidence rates, embryogenesis,growth,clinical features,risk of malignancy and the prognosis are highlighted systematically.The roles of various diagnostic modalities including ultrasound, CT,MRI,fine needle aspiration cytology(FNAC), immunohistochemistry and surgery are further discussed. RESULTS:The mean age of patients with CHFC was 48± 12 years.The male/female ratio was 1.1∶1.The majority of patients with CHFC(62%)were asymptomatic,and the common mode of presentation was right upper abdominal pain.The cysts occurred in the left lobe in 51 patients, with sole location in segmentⅣin 44,and in the right lobe in 26.The average size of the cysts was 3.6±2.12 cm. The majority of the cysts were unilocular,and only 7 cases were multilocular.Cyst contents were described as viscous or mucinous in 73 patients,whereas bilious fluid was noted in 3.Large cysts having squamous carcinoma were cited in 3 patients,and 2 had extensive squamous metaplasia without malignancy.Others had benign histopathology. CONCLUSIONS:Clinicians have become increasingly aware of CHFC.Imaging alone is not diagnostic per se, but when considered in the context of the global picture does provide important clues to the diagnosis.FNAC is diagnostic by the presence of the ciliated columnar aspirate but lacks sensitivity.Infantile presentation is usually accompanied by biliary communication and mandates a different surgical approach.The demonstration of malignant transformation in 3 cases and its fatal course emphasizes the need for surgical resection in all cases once the diagnosis is made. | Sharad Sharma Amanda G.Dean Ayumi Corn Vivek Kohli Harlan I Wright Anthony Sebastian Nicolas Jabbour | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，6： | 2 |
| 4 | Lackof hepcidin gene expression and severe tissue iron o- verload in upstream stimulatory factor 2 (USF2) knockout mice 显示文摘 | NICOLAS G BENNOUN M DEVAUX I | 2001 | Proceedings of the National Acad- emy of Sciences of the United States of America2001，98，15： | 1 |
| 5 | Quaternion-MUSIC for vector-sensor array processing 显示文摘 | SEBASTIAN M NICOLAS L B JEROME I M | 2006 | IEEE Transactions on Signal Processing2006，54，4： | 1 |
| 6 | Driving Blind:Strategic Decision-making in Small Companies显示文摘 | Brouthers K.D Andriessen F Nicolaes I | | 0，，： | 1 |
| 7 | Lack of Hepcidin Gene Expression and Severe Tissue Iron Overload in Upstream Stimulatory Factor 2 (USF2) Knockout Mice显示文摘 | Nicolas G Bennoun M Devaux I | 2001 | PNAS2001，98，15： | 1 |
| 8 | MUSIC algorithm for vector-sensors array using hiquaternions 显示文摘 | Nicolas Le Bihan Sebastian Miron Mars J I | 2007 | IEEE Trans Signal Processing2007，55，9： | 1 |
| 9 | Microvascular obstruction assessed by 3 - tesla magnetic resonance imaging in acute myocardial infarction:correlation with plasma troponin I levels显示文摘 | Charles D Jerome I Nicolas M | 2010 | J Am Coll Cardiol2010，55，10： | 1 |
| 10 | Perceived Informa- tion Quality in Data Exchanges:Effects on Risk,Trust, and Intention to Use显示文摘 | NICOLAOU A I MCKNIGHT D H | 2006 | Information Systems Research2006，17，4： | 1 |
| 11 | Enzy- matic effect of hypoderminA, a parasite protease, on bovine lympho- cyte membrane antigens显示文摘 | MOIRE N NICOLAS - GAULARD I LE VERN Y | 1997 | Parasite Immunel1997，19，1： | 1 |
| 12 | MicroSAGE analysis of 2, 353 expressed genes in a single cell-derived colony of undifferentiated human mesenchymal stem cells reveals mRNAs of multiple cell lineages 显示文摘 | Nicola T Jarmo K David I | 2001 | Stem Cells2001，19，5： | 1 |
| 13 | Flavonoids: old and new aspects of a class of natural therapeutic drugs 显示文摘 | GIULIA D C NICOLA M ANGELO A I | 1999 | Life Sciences1999，65，4： | 1 |
| 14 | Effect of the parasite enzyme, hypoderminA, on bovine lymphocyte proliferation and interleukin -2 production via the prostaglandin pathway 显示文摘 | NICOLAS - GAULARD I MOIRE N BOULARD C | 1995 | lmmunelogy1995，85，1： | 1 |
| 15 | Folate status of reproductive age women and neural tube defect risk:The effect of long-term folic acid supplementation at doses of 140 tg and 400 μg per day显示文摘 | Nicola A Hursthouse I Andrew R | | 0，，： | 1 |
| 16 | Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice 显示文摘 | Nicolas G Bennoun M Devaux I | 2001 | Proc Natl Acad Sci USA2001，98，15： | 1 |
| 17 | Early inhaled nitric oxide im- proves oxidative balance in very preterm infants 显示文摘 | Hamon I Fresson J Nicolas MB | 2005 | Pediatr Res2005，57，5： | 1 |
| 18 | Retroperitoneal fi-brosis :typical and atypical manifestations 显示文摘 | Vivas I Nicolas Al Velazquez P | 2000 | Br J Radiol2000，73，： | 1 |
| 19 | French scallops: a new host for ostreid herpesvirus-1显示文摘 | Nicolas J L Davison A J Renault T | 2001 | Virology2001，290，： | 1 |
| 20 | Lack of hepcidin gene expression and severe tissue iron overload in up stream stimulatory factor 2 (USF2) knockout mice显示文摘 | Nicolas G Bennoun M Devaux I | 2001 | Proc Natl Acad Sci USA2001，98，： | 1 |
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