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| 1 | Metabolic syndrome and colorectal neoplasms:An ominous association显示文摘AIM:To evaluate the association of metabolic syndrome(MS) and colorectal cancer and adenomas in a Western country,where the incidence of MS is over 27%.METHODS:This was a prospective study between March 2013 and March 2014.MS was diagnosed according to the National Cholesterol Education ProgramATP III.Demographic characteristics,anthropometric measurements,metabolic risk factors,and colonoscopic pathologic findings were assessed in patients with MS(group 1) who underwent routine colonoscopy at our department.This data was compared with consecutive patients without metabolic syndrome(group 2),with no differences regarding sex and age.Patients with incomplete colonoscopy,family history,or past history of colorectal neoplasm were excluded.Informed consent was obtained and the ethics committee approved this study.Statistical analysis was performed using Student's t-test and χ2 test,with a P value ≤ 0.05 being considered statistically significant.RESULTS:Of 258 patients,129 had MS;51% males;mean-age 67.1 years(50-87).Among the MS group,94% had high blood pressure,91% had increased waist circumference,60% had diabetes,55% had low high-density lipoprotein cholesterol level,50% had increased triglyceride level,and 54% were obese [body mass index(BMI) 30 kg/m2].51% presented 4 criteria of MS.MS was associated with increased prevalence of adenomas(43% vs 25%,P = 0.004) and colorectal cancer(13% vs 5%,P = 0.027),compared with patients without MS.MS was also positively associated with multiple(≥ 3) adenomas(35% vs 9%,P = 0.024) and sessile adenomas(69% vs 53%,P = 0.05).No difference existed between location(P = 0.086),grade of dysplasia(P = 0.196),or size(P= 0.841) of adenomas.In addition,no difference was found between BMI(P = 0.078),smoking(P = 0.146),alcohol consumption(P = 0.231),and the presence of adenomas.CONCLUSION:MS is positively associated with adenomas and colorectal cancer.However,there is not enough information in western European countries to justify screening in patients with MS.To our knowledge,no previous study has evaluated this association in Portuguese patients. | Daniel Trabulo Suzane Ribeiro Cláudio Martins Cristina Teixeira Cláudia Cardoso Jo?o Mangualde Ricardo Freire élia Gamito Ana L Alves Fátima Augusto Ana P Oliveira Isabelle Cremers | 2015 | World Journal of Gastroenterology2015，21，17： | 5 |
| 2 | Appropriateness of outpatient gastrointestinal endoscopy in a non-academic hospital显示文摘AIM:To assess the appropriate use and the diagnostic yield of upper gastrointestinal endoscopy and colonoscopy in this subgroup of patients.METHODS:In total,789 consecutive outpatients referred for gastrointestinal(GI) endoscopy [381 for esophagogastroduodenoscopy(EGD) and 408 for colonoscopy] were prospectively enrolled in the study.The American Society for Gastrointestinal Endoscopy(ASGE) guidelines were used to assess the relationship between appropriateness and the presence of relevant endoscopic f indings.RESULTS:The overall inappropriate rate was 13.3%.The indications for EGD and colonoscopy were,respectively,appropriate in 82.7% and 82.6% of the exams,uncertain in 5.8% and 2.4% and inappropriate in 11.5% and 15%.The diagnostic yield was signif icant higher forEGDs and colonoscopies judged appropriate and uncertain when compared with those considered inappropriate(EGD:36.6% vs 36.4% vs 11.4%,P = 0.004;Colonoscopy:24.3% vs 20.0% vs 3.3%,P = 0.001).Of the 25 malignant lesions detected,all but one was detected in exams judged appropriate or uncertain.CONCLUSION:This study shows a good adherence to ASGE guidelines by the referring physicians and a significant increase of the diagnostic yield in appropriate examinations,namely in detecting neoplastic lesions.It underscores the importance that the appropriateness of the indication assumes in assuring high-quality GI endoscopic procedures. | Joo Mangualde Marie I Cremers Ana M Vieira Ricardo Freire lia Gamito Cristina Lobato Ana L Alves Fátima Augusto Ana P Oliveira | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，10： | 2 |
| 3 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 4 | Highly polymorphic microsatellite for identification of Candida albicans strains 显示文摘 | Sampaio P Gusmao L Alves C | 2003 | J Clin Microbiol2003，41，2： | 1 |
| 5 | End-to-end joining of tubes by plastic instability 显示文摘 | Alves L M Silva C M A Martins P A F | 2014 | Journal of Materials Processing Technology2014，214，9： | 1 |
| 6 | Support vector machines for transient stability analysis of large-scale power systems显示文摘 | Moulin L S Alves da Silva A P El-Sharkawi M A | 2004 | IEEE Transactions on Power Systems2004，19，2： | 1 |
| 7 | Parameterized fast deeoupled power flow methods for obtaining the maximum loading point of power systems Part Ⅰ and Part Ⅱ显示文摘 | Alves D A Da Silva L C P Castro C A | 2004 | Electric Power Systems Research2004，69，： | 1 |
| 8 | Mining user con- textual preferences 显示文摘 | DE AMO S BUENO M L P ALVES G | 2013 | Journal of InfmTnation & Data Manage- ment2013，4，1： | 1 |
| 9 | Thermal decom- position and structural reconstruction effect on Mg-Fe-based hydro- talcite compounds 显示文摘 | Ferreira O P Alves O L Gouveia D X et ol | 2004 | Journal of Solid State Chemistry2004，177，9： | 1 |
| 10 | Expansion and reduction of thin-walled tubes using a die : Experimental and theoretical investigation 显示文摘 | Almeida B P P Alves M L Rosa P A R | 2006 | International Journal of Machine Tools and Manufacture2006，46，1213： | 1 |
| 11 | Cold expansion and reduction of thin- walled PVC tubes using a die显示文摘 | Alves L M Martins P A F | 2009 | Journal of Materials Processing Technology2009，209，9： | 1 |
| 12 | A fuzzy classified vector quantizer for image coding显示文摘 | Corte-Real L Alves A P | 1995 | IEEE Transactions on Communication1995，43，234： | 1 |
| 13 | Ochratoxin A in some Portuguese wines: method validation and screening in Port wine and Vinho Verde显示文摘 | Festas I Herbert P Santos L Cabral M Barros P Alves A | 2000 | American Journal of Enology and Viticulture2000，51，2： | 1 |
| 14 | Cream cheese as a symbiotic food carrier using B ifidobacterium animalis B b‐12 and L actobacillus acidophilus L a‐5 and inulin显示文摘 | Larissa L Alves Neila S P S Richards Paula Mattanna Diego F Andrade Adriano P S Rezer Liana I G Milani Adriano G Cruz José A F Faria | 2012 | Int J Dairy Technol2012，，1： | 1 |
| 15 | Forming of thin-walled hollow spheres using sacrificial polymer mandrels显示文摘 | Alves L M Pardal T C D Martins P A F | 2009 | International Journal of Machine Tools and Manufacture2009，49，6： | 1 |
| 16 | Compression bead- ing and nosing of thin-walled tubes using a die : Experimental and theoretical investigation 显示文摘 | Gouveia B P P Alves M L Rosa P A R | 2006 | International Journal of Mechanics & Materials in Design2006，3，1： | 1 |
| 17 | Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin显示文摘 | Alves DS Pérez-Fons L Estepa A | 2004 | Biochem Pharmacol2004，68，3： | 1 |
| 18 | Effect of xylo oligosac eharides from corn cobs autohydrolysis on the intestinal microbiota of piglets after weaning 显示文摘 | Moura P Marques S Alves L | 2007 | Livestock Science2007，108，： | 1 |
| 19 | Magnetic behaviour of a nanocrystallized Fe73Si15B8Nb3Cu1显示文摘 | Waeckerle T Alves F Reydet P L | 2003 | J Magn Magn Mater2003，，254255： | 1 |
| 20 | Tube branching by asymmetric com- pression beading 显示文摘 | Alves L M Martins P A F | 2012 | Journal of Materials Processing Technology2012，212，5： | 1 |
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