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| 1 | Delayed gastric emptying is associated with pylorus-preserving but not classical Whipple pancreaticoduodenectomy:A review of the literature and critical reappraisal of the implicated pathomechanism显示文摘Pylorus-preserving pancreaticoduodenectomy (PPPD) is nowadays considered the treatment of choice for periampullary tumors, namely carcinoma of the head, neck, or uncinate process of the pancreas, the ampulla of Vater, distal common bile duct or carcinoma of the peri-Vaterian duodenum. Delayed gastric emptying (DGE) comprises one of the most troublesome complications of this procedure. A search of the literature using Pubmed/Medline was performed to identify clinical trials examining the incidence rate of DGE following standard Whipple pancreaticoduodenectomy (PD) vs PPPD. Additionally we performed a thorough in-depth analysis of the implicated pathomechanism underlying the occurrence of DGE after PPPD. In contrast to early studies, the majority of recently performed clinical trials demonstrated no significant association between the occurrence of DGE with either PD or PPPD. PD and PPPD procedures are equally effective operations regarding the postoperative occurrence of DGE. Further randomized trials are required to investigate the effi cacy of a recently reported (but not yet tested in large- scale studies) modifi cation, that is, PPPD with antecolic duodenojejunostomy. | Kosmas I Paraskevas Costas Avgerinos Costas Manes Dimitris Lytras Christos Dervenis | 2006 | World Journal of Gastroenterology2006，12，37： | 16 |
| 2 | How to identify which patients with asymptomatic carotid stenosis could benefit from endarterectomy or stenting显示文摘Offering routine carotid endarterectomy(CEA)or carotid artery stenting(CAS)to patients with asymptomatic carotid artery stenosis(ACS)is no longer considered as the optimal management of these patients.Equally suboptimal,however,is the policy of offering only best medical treatment(BMT)to all patients with ACS and not considering any of them for prophylactic CEA.In the last few years,there have been many studies aiming to identify reliable predictors of future cerebrovascular events that would allow the identification of patients with high-risk ACS and offer a prophylactic carotid intervention only to these patients to prevent them from becoming symptomatic.All patients with ACS should receive BMT.The present article will summarise the evidence suggesting ways to identify these high-risk asymptomatic individuals,namely:(1)microemboli detection on transcranial Doppler,(2)plaque echolucency on Duplex ultrasound,(3)progression in the severity of ACS,(4)silent embolic infarcts on brain CT/MRI,(5)reduced cerebrovascular reserve,(6)increased size of juxtaluminal hypoechoic area,(7)identification of intraplaque haemorrhage using MRI and(8)carotid ulceration.The evidence suggests that approximately 10%-15%of patents with asymptomatic stenosis might benefit from intervention;this will become more clear after publication of ongoing studies comparing stenting or endarterectomy with best medical therapy.In the meantime,no patient should be offered intervention unless there is evidence of high risk of ipsilateral stroke,from modalities such as those discussed here. | Kosmas I Paraskevas Frank J Veith J David Spence | 2018 | Stroke & Vascular Neurology2018，3，2： | 10 |
| 3 | The role of fibrinogen and fibrinolysis in penpheral arterial disease 显示文摘 | Paraskevas K I Baker D M Vrentzos G E | 2008 | Thromb Res2008，122，： | 1 |
| 4 | Ropivaeaine spinal anesthesia is not antagonized by ondansetron pretreatment显示文摘 | PARASKEVA A CHATZIARA V SIAFAKA I | 2009 | Anesth Ana]g2009，109，5： | 1 |
| 5 | Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-lalpha显示文摘 | Mylonis I Chachami G Samiotaki M Panayotou G Paraskeva E Kalousi A | 2006 | J Biol Chem2006，281，33： | 1 |
| 6 | Adsorption of atrazine on soils:Model study显示文摘 | KOVAIOS I D PARASKEVA C A KOUTSOUKOS P G | 2006 | Journal of Colloid and Interface Science2006，299，： | 1 |
| 7 | The roleof fibrinogen and fibrinolysis in peripheral arterial disease显示文摘 | Paraskevas K I Baker D M Vrentzos G E | 2008 | Thromb Res2008，122，1： | 1 |
| 8 | The role of fibrinogen and fibrinolysis in peripheral arterial disease显示文摘 | Paraskevas K I Baker D M Vrentzos G E | | 0，，01： | 1 |
| 9 | Irradia-tion-induced carotid artery stenosis:a preventable complication of neck radiotherapy显示文摘 | Paraskevas K I Giannoukas A D Mikhailidis D P | | 0，，03： | 1 |
| 10 | 显示文摘 | Tsang S C Caps V Paraskevas I | 2004 | Angew Chem Int Ed2004，43，42： | 1 |
| 11 | Magnetically separable,carbon-supported nanocatalysts for the manufacture of fine chemicals显示文摘 | S C Tsang V Caps I Paraskevas | | 0，，42： | 1 |
| 12 | The diag- nostic value of tau protein, beta amyloid ( 1 42) and their ratio for the discrimination of alcohol related congnitivedisorders from Alzheimer's disease in the early stages 显示文摘 | Kapaki E Liappas I Paraskevas GP | 2005 | Int J Geriatr Psychiatry2005，20，8： | 1 |
| 13 | Ankle-bra-chial index:a marker of both peripheral arterial disease andsystemic atherosclerosis as well as a predictor of vascular e-vents显示文摘 | Paraskevas KI Kotsikoris I Koupidis SA | 2010 | Angiology2010，61，6： | 1 |
| 14 | Comparison of the five 2011 guidelines for the treatment of carotid stenosis显示文摘 | PARASKEVAS K I MIKHAILIDIS D P VEITH F J | 2012 | J Vasc Surg2012，55，5： | 1 |
| 15 | Carotid artery stenting may be losing the battle against carotid endarterectomy for the management of symptomatic carotid artery stenosis,but the jury is still out显示文摘 | PARASKEVAS K I MIKHAILIDIS D P VEITH F J | 2009 | Vascular2009，17，4： | 1 |
| 16 | Dyslipidemia as a risk factor for erectile dysfunction 显示文摘 | Vrentzos G E Paraskevas K I Mikhailidis D P | 2007 | Curr Med Chem2007，14，16： | 1 |
| 17 | Leptin:a promising therapeutic target with pleiotropic action besides body weight regulation显示文摘 | Paraskevas K I Liapis C D Mikhailidis D P | 2006 | Curr Drug Targets2006，7，6： | 1 |
| 18 | Ankle-brachial index: a marker of both peripheral arterial disease and systemic atherosclerosis as well as a predictor of vascular events显示文摘 | Paraskevas KI Kotsikoris I Koupidis SA | 2010 | Angiology2010，61，6： | 1 |
| 19 | The role offibrinogen and fibrinolysis in peripheral arterial disease 显示文摘 | Paraskevas K I Baker D M Vrentzos G E ei al | 2008 | Thrombosis Research2008，122，1： | 1 |
| 20 | Syntheses of carbon encapsulated magnetic FeNi nanoparticle via decompositions of methane and benzene显示文摘 | Paraskevas I Caps V Tsang S C | 2006 | Carbon2006，44，： | 1 |
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