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| 1 | Adenoid cystic carcinoma of breast: Recent advances显示文摘Adenoid cystic carcinoma(ACC) of the breast is a rare special subtype of breast cancer characterized by the presence of a dual cell population of luminal and basaloid cells arranged in specific growth patterns. Most breast cancers with triple-negative, basal-like breast features(i.e., tumors that are devoid of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression, and express basal cell markers) are generally high-grade tumors with an aggressive clinical course. Conversely, while ACCs also display a triple-negative, basal-like phenotype, they are usually low-grade and exhibit an indolent clinical behavior. Many discoveries regarding the molecular and genetic features of the ACC, including a specific chromosomal translocation t(6;9) that results in a MYB-NFIB fusion gene, have been made in recent years. This comprehensive review provides our experience with ACC of the breast, as well as an overview of clinical, histopathological, and molecular genetic features. | Kosuke Miyai Mary R Schwartz Mukul K Divatia Rose C Anton Yong Wook Park Alberto G Ayala Jae Y Ro | 2014 | World Journal of Clinical Cases2014,2,12: | 16 |
| 2 | 干扰素调节因子5通过损伤胞葬作用控制动脉粥样硬化病变中的坏死核心形成显示文摘髓系细胞是动脉粥样硬化病变发展和易损斑块形成的核心。动脉吞噬细胞吸收凋亡细胞(胞葬作用)的能力受损,可促进病变生长并建立坏死核心。干扰素调节因子(interferon regulatory factor,IRF)5是髓系细胞功能的重要调节因子。该研究试图确定IRF5是否影响动脉粥样硬化病变的形成和表型。方法:通过两种互补模型,研究IRF5在动脉粥样硬化中的作用: | Seneviratne AN Edsfeldt AO Cole JE Kassiteridi C Swart M Park I Green P Khoyratty TE Saliba DG Goddard ME Sansom SN Goncalves I Krams R Udalova IA Monaco C 刘莉 叶鹏 | 2017 | 中华高血压杂志2017,25,8: | 9 |
| 3 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012,22,1: | 7 |
| 4 | A novel system design for continuous processing of plastic/wood-fiber composite foams with improved cell morphology显示文摘 | Rizvi G M Pop-Iliev R Park C B | 2002 | Journal of Cellular Plastics2002,38,5: | 2 |
| 5 | Electric load forecasting using an artificial neural network 显示文摘 | Park D C El-Sharkawi M A Marks R J | 1991 | IEEE Transactions on Power Systems1991,6,2: | 2 |
| 6 | Collagen denaturation can be quantified in burnqd human skin using polarization-sensitive optical coherence tomography 显示文摘 | PIERCE M C SHERIDAN R L PARK B H | 2004 | Burns2004,30,6: | 1 |
| 7 | Combined use of active and passive surface waves显示文摘 | Park C B Miller R D Ryden N | | Journal of Engineering and Environmental Geophysics (JEEG)0,,: | 1 |
| 8 | Molecular and functional characterization of a cyclophilin with antifungal activity from Chinese cabbage 显示文摘 | Lee J R Park S C Kim J Y | 2007 | Biochem Biophys Res Commun2007,353,3: | 1 |
| 9 | The impact of behavior and addiction on psychological models of cigarette and alcohol use during pregnancy显示文摘 | Moore P J Turner R Park C L | 1996 | Addictive Behavior1996,21,5: | 1 |
| 10 | Competitive interactions between endogenous LTD and LTP in the hippoeampus underlie the storage of emo- tional memories and stress-induced amnesia 显示文摘 | Diamond D M Park C R Campbell A M Woodson J C | 2005 | Hip- pocampus2005,15,: | 1 |
| 11 | Semiparametric effi- cient estimation of AR(1) panel data models显示文摘 | Park B U Sickles R C Simar L | 2003 | Jour- nal of Econometrics2003,117,2: | 1 |
| 12 | Effects of Prior Knowledge and Ex- perience and Phase of the Choice Process on Consumer Deci- sion Processes: A Protocol Analysis 显示文摘 | Bettman J R Park C W | 1980 | Journal of Consumer Research1980,7,6: | 1 |
| 13 | Kojic acid - amino acid amide metal complexes and their melanogenesis inhibitory activities 显示文摘 | KWAK S Y CHOI H R PARK K C | 2011 | J Pept Sci2011,17,: | 1 |
| 14 | Characterization of a heat-stable protein with antimicrobial activity from Arabidopsis thaliana显示文摘 | Park S C Lee J R Shin S O Park Y Lee S Y Hahm K S | | 0,,03: | 1 |
| 15 | Design of robust adaptive frequency hopping for wireless medical telemetry systems显示文摘 | Park K J Park T R Schmitz C D | | 0,,02: | 1 |
| 16 | Molecular aggregation of disklike benzene tri-carboxamides containing di-acety- lenic groups in bulk and organic solvents显示文摘 | LEE S J PARK C R CHANG J Y | 2004 | Langmuir2004,20,22: | 1 |
| 17 | Cytoprotective activity of gly- cyrrhizae radix extract against arsenite - induced cytotoxicity 显示文摘 | KIM S C PARK S J LEE J R | 2008 | Evid Based Complement Alternat Med2008,5,2: | 1 |
| 18 | Molecular and functional characterization of a cyclophilin with antifungal activity from Chinese cabbage 显示文摘 | LEE J R PARK S C KIM J Y LEE S S PARK Y CHEONG G W HAHM K S LEE S Y | 2007 | Biochem Biophys Res Commun2007,353,3: | 1 |
| 19 | Variation in poly-phenol oxidase activity and quality characteristics among hard white wheat and hard red winter wheat samples 显示文摘 | Park W J Shelton D R Peterson C J | 1997 | Cereal Chemistry1997,74,: | 1 |
| 20 | Numerical flow analysis of single-stage ducted marine propulsor 显示文摘 | Park W G Jung Y R Kim C K | 2005 | Ocean Engineering2005,32,10: | 1 |