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| 1 | Portal vein thrombosis, mortality and hepatic decompensation in patients with cirrhosis: A meta-analysis显示文摘AIM: To determine the clinical impact of portal vein thrombosis in terms of both mortality and hepatic decompensations(variceal hemorrhage, ascites, portosystemic encephalopathy) in adult patients with cirrhosis.METHODS: We identified original articles reported through February 2015 in MEDLINE, Scopus, Science Citation Index, AMED, the Cochrane Library, and relevant examples available in the grey literature. Two independent reviewers screened all citations for inclusion criteria and extracted summary data. Random effects odds ratios were calculated to obtain aggregate estimates of effect size across included studies, with 95%CI.RESULTS: A total of 226 citations were identified and reviewed, and 3 studies with 2436 participants were included in the meta-analysis of summary effect. Patients with portal vein thrombosis had an increased risk of mortality(OR = 1.62, 95%CI: 1.11-2.36, P = 0.01). Portal vein thrombosis was associated with an increased risk of ascites(OR = 2.52, 95%CI: 1.63-3.89, P < 0.001). There was insufficient data available to determine the pooled effect on other markers of decompensation including gastroesophageal variceal bleeding or hepatic encephalopathy. CONCLUSION: Portal vein thrombosis appears to increase mortality and ascites, however, the relatively small number of included studies limits more generalizable conclusions. More trials with a direct comparison group are needed. | Jonathan G Stine Puja M Shah Scott L Cornella Sean R Rudnick Marwan S Ghabril George J Stukenborg Patrick G Northup | 2015 | World Journal of Hepatology2015，7，27： | 42 |
| 2 | Spontaneous bacterial peritonitis prevalence in pretransplant patients and its effect on survival and graft loss post-transplant显示文摘AIM To investigate the incidence of spontaneous bacterial peritonitis(SBP) in pre-transplant patients and its effect on post transplant mortality and graft failure. METHODS We conducted a retrospective cohort study of patient records from the organ procurement and transplant network data set. Patients were identified by the presence of SBP pre-transplant. Univariate post-transplant survival models were constructed using the Kaplan-Meier technique and multivariate models were constructed using the Cox proportional hazards model. Variables that affected post-transplant graft survival were identified in the SBP population. RESULTS Forty-seven thousand eight hundred and eighty patient records were included in the analysis for both groups, and 1966(4.11%) patients were identified in the data set as having pre-transplant SBP. Patients that had pre-transplant SBP had higher rates of graft loss from recurrent hepatitis C virus(HCV)(3.6% vs 2.0%, P < 0.0001), infections leading to graft loss(1.9% vs 1.3%, P = 0.02), primary non-function(4.3% vs 3.0%, P < 0.0001) and chronic rejection(1.1% vs 0.7%, P = 0.04). Kaplan-Meier survival analysis showed a statistically significant difference in all-cause survival in patients with a history of SBP vs those without(P < 0.0001). Pretransplant history of SBP was independently predictiveof mortality due to recurrent HCV(HR = 1.11, 95%CI: 1.02-1.21, P < 0.017) after liver transplantation.CONCLUSION HCV patients prior to the advent of directing acting anti-viral agents had a higher incidence of pre-transplant SBP than other patients on the liver transplant wait list. SBP history pre-transplant resulted in a higher rate of graft loss due to recurrent HCV infection and chronic rejection. | Neeral L Shah Nicolas M Intagliata Zachary H Henry Curtis K Argo Patrick G Northup | 2016 | World Journal of Hepatology2016，8，36： | 2 |
| 3 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003，，8： | 2 |
| 4 | Whorl and stalk dam- age by European and Southwestern corn borers to four events of Bacillus thuringiensis transgenic maize 显示文摘 | Archer T L Schuster G Patrick C | 2000 | Crop Protec- tion2000，19，3： | 1 |
| 5 | Synthesis and scale-up of HNIW from 2, 6, 8, 12-tetraacetyl-4, 10-dibenzyl-2, 4, 6, 8, 10, 12-hexaazaisowurtzitane显示文摘 | Nikolaj V L Ulf W Patrick G | 2000 | Org Proc Res & Development2000，4，3： | 1 |
| 6 | Synthesis and Application of Some Polycondensable Fluorescent Dyes 显示文摘 | Patrick L G F Whiting A | 2002 | Dyes and Pigments2002，52，2： | 1 |
| 7 | Synthesis and scale-up of HNIW from 2,6,8,12-tetraacetyl-4,10-dibenzyl-2,4,6,8,10,12-hexaazaisowurtzitane显示文摘 | V L Nikolaj W Ulf G Patrick | 2000 | Org Proc Res & Develop2000，4，3： | 1 |
| 8 | MR monitoring of laserinduced lesions of the liver in vivo in a low-field open magnet:temperature mapping and lesion size prediction显示文摘 | Delphine G Patrick C Alexandre L | 2001 | JMRI2001，13，： | 1 |
| 9 | Extraction of proteins from plant tissues for two-dimensional electrophoresis analysis显示文摘 | Patrick G Eckhardn Hans L | 2003 | Eleclrophoresis2003，24，1： | 1 |
| 10 | Sesquiterpenes from clove (Eugenia caryophyllata) as potential antlcarcinogenie agents显示文摘 | Zheng G Q Patrick M K Luke K T L | 1992 | J Natur Pro1992，55，7： | 1 |
| 11 | Adaptive wavelet transform for vibration signal modeling and application in fault diagnosis of water hydraulic motor 显示文摘 | Chen H X Patrick S K Chua G H L | 2006 | Mechanical Systems and Signal Processing2006，，20： | 1 |
| 12 | 显示文摘 | Marc L Patrick G Mircea A M | 2009 | International Journal of Pharmaceutics2009，382，12： | 1 |
| 13 | V ertica 1 Integ ra tionin Am er icanM anufacturing, 1899-1948显示文摘 | Harold C L ivesay Patrick G Porter | 1969 | The Journalof Econom icH isto ry1969，29，3： | 1 |
| 14 | Quality of life of persons with urinary incontinence: Development of a new measure 显示文摘 | Wagner T H Patrick D L Bavendam T G | 1996 | Urology1996，47，： | 1 |
| 15 | The kinetics of the hydriding of uranium metal显示文摘 | POWELL G L HARPER W L KIRK- PATRICK J R | 1991 | J Less-Common Met1991，，： | 1 |
| 16 | Clinical indications for noninvasive positive pressure ventilation in chronic respiratory failure due to restrictive lung disease,COPD,and nocturnal hypoventilation -a consensus conference report显示文摘 | Allen G Patrick L Nicholas H | | 0，，2： | 1 |
| 17 | Whorl and stalk damage by European and Southwestern corn borers to four events of Bacillus thuringiensis transgenic maize crop显示文摘 | Archer T L Schuster G Patrick C | 2000 | Protection2000，19，3： | 1 |
| 18 | Disease outbreak detection system using syndromic data in the greater Washington DC area 1 1 Information for the full text of this article is available via AJPM Online at www.ajpm-online.net.显示文摘 | Michael D Lewis Julie A Pavlin Jay L Mansfield Sheilah O’Brien Louis G Boomsma Yevgeniy Elbert Patrick W Kelley | 2002 | American Journal of Preventive Medicine2002，，3： | 1 |
| 19 | Conversion of p35 to p25Deregulates cdk5 activity and promotes neurodegeneration显示文摘 | Patrick G N Zukerberg L Nikolic M et a1 | 1999 | Nature1999，402，6762： | 1 |
| 20 | Singapore venture capitalists (VSC) investment evaluation criteria:a re-examination显示文摘 | WEE L T PATRICK G G | 1999 | Small Business Economics1999，，13： | 1 |
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