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| 1 | 常规脂蛋白检测和载脂蛋白在心血管病预测中的比较显示文摘总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀类药物、有相关的脂质指标(n=346 686)的受试者。 | Welsh C Celis-Morales CA Brown R Mackay DF Lewsey J Mark PB Gray SR Ferguson LD Anderson JJ Lyall DM Cleland JG Jhund PS Gill J MR Pell JP Sattar N Welsh P 刘青(译) 叶鹏(摘、审校) | 2019 | 中华高血压杂志2019，27，7： | 10 |
| 2 | Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development显示文摘cytosine 的 Methylation 是与基因压抑联系的 DNA 修正。最近,新奇 cytosine 修正, 5-hydroxymethylcytosine (5-hmC ) 被发现了。这里,我们在哺乳动物的开发期间并且在细胞的系统检验 5-hmC 分发,并且证明 5-hmC 的发展动力学与 5-methylcytosine (5-mC ) 的那些不同;特别地 5-hmC 与成年纸巾相比在胚胎的上下文被充实。一个可检测的 5-hmC 信号在在父亲的染色体受到 5-mC 的染色体宽的 hydroxylation 的地方,在接合子阶段开始的培植前开发出现,它精确在父亲的前核与 5-mC 信号的损失与一致。5-hmC 的层次与在老鼠的表示 nestin 房间人口在在胚囊,和修正 colocalises 的内部房间团的房间高培植以后的胚胎。比作另外的成年哺乳动物的机关, 5-hmC 强烈在骨头髓和大脑被充实, 5-hmC 内容在那里高是 neuronal 祖先和 mitotic 以后神经原的一个特征。我们证明 5-hmC 的那高水平是在老鼠和人的胚胎的干细胞(转换字符) 的不仅现在并且,在区别期间输以前被报导了,而且在导致的 pluripotent 干细胞的产生期间重现;因此, 5-hmC 丰富与一个 pluripotent 房间状态相关。我们的调查结果建议除了 neuronal 系的房间, genomic 5-hmC 的高水平是胚胎的房间人口和细胞的 pluri 系和多系力量的一个 epigenetic 特征。到我们的知识, 5-hmC 那么代表其丰富是的发现的 DNA 的第一 epigenetic 修正房间类型特定。 | Alexey Ruzov Yanina Tsenkina Andrea Serio Tatiana Dudnakova Judy Fletcher Yu Bai Tatiana Chebotareva Steve Pells Zara Hannoun Gareth Sullivan Siddharthan Chandran David C Hay Mark Bradley Ian Wilmut Paul De Sousa | 2011 | Cell Research2011，21，9： | 4 |
| 3 | Detection and characterization of putative metastatic precursor cells in cancer patients显示文摘 | Aiix-Panabières C Vendrell J-P Pellé O | 2007 | Clin Chem2007，53，： | 1 |
| 4 | Stages in the development of thick cobalt oxide films exhibiting reversible redox behavior and pseudocapacitance显示文摘 | LIU T C PELL W G CONWAY B E | 1999 | Electrochimica Acta1999，44，17： | 1 |
| 5 | Diagnostic analyses for mechanisms of self-discharge of electrochemical capaci- tors and batteries显示文摘 | Brian E B Pell W G Liu T C | 1997 | Journal of Power Sources1997，65，12： | 1 |
| 6 | Prediction of ruminal volatile fatty acids and pH within thd net carbohydrate and protein system显示文摘 | Pitt R E Van Kessel J S Fox D G Pell A N Barry M C Van Soest P J | 1996 | Journal of Animal Science1996，74，： | 1 |
| 7 | Detection and characterization of putative metastatic precursor cells in cancer patients显示文摘 | Alix-Panabieres C Vendrell JP Pelle O | 2007 | Clin Chem2007，53，3： | 1 |
| 8 | Predictingcesarean section and uterine rupture among women at-tempting vaginal birth after prior cesarean section显示文摘 | Smith G C White I R Pell J P Dobbie R | 2005 | PLoS Med2005，2，： | 1 |
| 9 | Microbial adaptation,process performance and a suggested control strategy in a pre-denitrification system with ethanol dosage显示文摘 | HALLIN S LINDBERG C F PELL M | 1996 | Wat Sci Tech1996，34，12： | 1 |
| 10 | Detection and characterization of putative metastatic precursor ceils in cancer patients显示文摘 | Alix-Panabieres C Vendrell JP Pelle O | 2007 | Clin Chem2007，53，： | 1 |
| 11 | Complexity of coupled human and natural systems显示文摘 | Liu J Dietz T Carpenter SR Alberti M Folke C Moran E Pell AN Deadman P Kratz T Lubchenco J Ostrom E Ouyang Z Provencher W Redman CL Schneider SH Taylor WW | 2007 | Science2007，317，： | 1 |
| 12 | The movements of the components of the Hastings bipolar prosthesis 显示文摘 | Chen S C Badrinath K Pell L H | 1989 | J Bone Joint Surg Br1989，71，2： | 1 |
| 13 | Detection and characterization of putative metastatic precursor cells in cancer patients显示文摘 | Alix-Panabieres C Vendrell JP Pelle O | 2007 | Clin Chem2007，53，3： | 1 |
| 14 | Ozone-induced oxidative stress:mechanisms of action and reaction显示文摘 | Pell E J Schlagnhaufer C D Arteca R N | 1997 | Physiologia Plantarum1997，100，： | 1 |
| 15 | Self discharge and potential recovery phenomena at thermally and electrochemically prepared RuO2 supercapacitor electrodes 显示文摘 | Liu T C Pell W G Conway B E | 1997 | Electrochim Aeta1997，42，23： | 1 |
| 16 | The effect of a ruminal nitrogen (N) deficiency in dairy cows: evaluation of the Cornell Net Carbohydrate and Protein System ruminal nitrogen deficiency adjustment显示文摘 | Ruiz R Tedeschi L O Marini J C Fox D G Pell A N Jarvis G Russell J B | 2002 | Journal of Dairy Science2002，85，： | 1 |
| 17 | Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons显示文摘 | Pelled D Raveh T Riebeling C | 2002 | J Biol Chem2002，277，19： | 1 |
| 18 | Finite element simulation of destructive tire testing显示文摘 | Tseng N T Pelle R G Warholic T C | 1991 | Tire Science and Technology1991，19，1： | 1 |
| 19 | Sequential expression of two 1-aminocyclopropane-1-carboxylate synthase gene in response to biotic and abiotic stresses in potato leaves 显示文摘 | SCHLAGNHAUFER C ARTECA R PELL E | 1997 | Plant Mol Biol1997，35，： | 1 |
| 20 | Differential actions of growth hormone and insulin like growth factor-1 on tissue protein metabolism in dwarf mice 显示文摘 | Pell J M Bates P C | 1992 | Endocrinology1992，130，： | 1 |
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