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| 1 | Therapeutic effect of transcatheter arterial chemoembolization and percutaneous injection of acetic acids on primary liver cancer显示文摘BACKGROUND: The resection rate of primary liver tumor in China is only about 20%. A lot of patients with moderate and advanced liver tumor may lose the chance of opera- tion. The objective of present research was to study the ef- ficacy of transcatheter arterial chemoembolization (TACE) combined with percutaneous injection of chemical agents and acetic acids in the treatment of patients with primary liver cancer (PLC). METHODS: Thirty-three patients with middle and ad- vanced stage of PLC were divided into two groups: percu- taneous injection of chemical agents and acetic acids (15 patients, group A) and TACE (18 patients, group B). RESULTS: Tumor diameter and serum AFP level reduced to 86.6% and 83.3% in group A, and 55.5% and 40% in group B, respectively. There was significant difference be- tween the two groups ( P < 0 . 0 1 ) . The 1-, 2-, 3-, 4-year survival rates of group A were 96.7%, 86.6%, 51.3%, 33.3%, respectively and in group B were 66.7%, 44.4%, 16.7%, 0%, respectively (P<0.01). CONCLUSION: TACE combined with percutaneous injec- tion of chemical agents and acetic acids is efficacious to in- crease the survival rate of patients with PLC. | Hong-Bin Chen, Yue Huang, Dong-Ling Dai, Xia Zhang, Zhong-Wen Huang, Qi-Kai Zhang, Hui-Hua Wang, Jun-Su Zhang and Ge Pan Sanming, China Departments of Gastroenterology , Interventional Therapy , Ultrasonography and CT , Sanming Municipal First Hospital, Sanming 365000, China Department of Gastroenterology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400000, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，1： | 4 |
| 2 | Murine fertilized ovum, blastomere and morula cells lacking SP phenotype显示文摘In the field of stem cell research, SP (side population) phenotype is used to define the property that cells maintain a high efflux capability for some fluorescent dye, such as Hoechst 33342. Recently, many researches proposed that SP phenotype is a phenotype shared by some stem cells and some pro- genitor cells, and that SP phenotype is regarded as a candidate purification marker for stem cells. In this research, murine fertilized ova (including conjugate and single nucleus fertilized ova), 2-cell stage and 8-cell stage blastomeres, morulas and blastocysts were isolated and directly stained by Hoechst 33342 dye. The results show that fertilized ovum, blastomere and morula cells do not demonstrate any ability to efflux the dye. However, the inner cell mass (ICM) cells of blastocyst exhibit SP phenotype, which is consistent with the result of embryonic stem cells (ESCs) in vitro. These results indicate that the SP phenotype of ICM-derived ESCs is an intrinsic property and independent of the culture condition in vitro, and that SP phenotype is one of the characteristics of at least some pluripotent stem cells, but is not shared by totipotent stem cells. In addition, the result that the SP phenotype of ICM cells disap- peared when the inhibitor verapamil was added into medium implies that the SP phenotype is directly associated with ABCG2. These results suggest that not all the stem cells demonstrate SP phenotype, and that SP phenotype might act as a purification marker for partial stem cells such as some pluripo- tent embryonic stem cells and multipotent adult stem cells, but not for all stem cells exampled by the totipotent stem cells in the very early stage of mouse embryos. | XU YiXin1, HE ZhiYing2, ZHU HaiYing2, CHEN XueSong2, LI JianXiu2, ZHANG HongXia2, PAN XingHua3 & HU YiPing2 1 ChangZheng Hospital, affiliated to Second Military Medical University, Shanghai 200003, China 2 Department of Cell Biology, Second Military Medical University, Shanghai 200433, China 3 Department of Genetics, Yale University School of Medicine, New Haven, CT 06519, USA | 2007 | Science China(Life Sciences)2007，50，6： | 2 |
| 3 | Mutations in the DNAH1 I (axonemal heavy chain dynein type I 1 ) gene cause one form of situs inversus totalis and most likely primary cili- ary dyskinesia显示文摘 | 13artoloni L Blouin JL Pan Y ct al | 2002 | roe Natl Acad Sci USA2002，99，10： | 1 |
| 4 | PKC mediates fluetuant ERK-paxillin signaling for hepatocyte growth factor-in- duced migration of hepatoma cell HepG2 显示文摘 | Hu CT Cheng CC Pan SM | 2013 | Cell Signal2013，25，6： | 1 |
| 5 | Mitogenic effect of oxidized low density lipoprotein on vascular smooth musele cells mediated by activation of Ras/Raf/MEK/MAPK pathway 显示文摘 | Chien CS Hsiao LD Pan SL wang CC Chiu CT Lin CC | 2001 | Br J Pharmacol2001，132，： | 1 |
| 6 | Cyclooxygenasc 2 Cpregulates CCR7 via EP2/EP4 Receptor Signaling Pathways to Enhance Lymphatic Invasion of Breast Cancer Cells显示文摘 | Pan MR Hou MF Chang HC ct al | 2008 | J Biol Chem2008，283，11： | 1 |
| 7 | Drug therapy for ulcerative colitis显示文摘 | Xu CT Meng SY Pan BR | 2004 | World J Gastroenterol2004，10，16： | 1 |
| 8 | Glil inhibition induces cell -cycle arrest and enhanced apoptosis in brain glioma cell lines 显示文摘 | Wang K Pan L Che X ct al | 2010 | J Neuroonco12010，98，3： | 1 |
| 9 | Drug therapy for ulcerative colitis显示文摘 | XU CT MENG SY PAN BR | 2004 | World J Gatroenterol2004，10，16： | 1 |
| 10 | Drug therapy for ulcerative colitis 显示文摘 | Xu CT Meng SY Pan BR | 2004 | World J Gastroenrol2004，10，16： | 1 |
| 11 | Suppression of lipopolysaccharide-induced nuclear factor-kappaB activity by theaflavin-3,3'-digallate from black tea and other polyphenols through down-regulation of IkappaB kinase activity in macrophages显示文摘 | Pan MH Lin-Shiau SY Ho CT | 2000 | Biochem Pharmacol2000，59，4： | 1 |
| 12 | Enhancement of analgesic effect of intrathecal neostigmine and clonidine on bupivacaine spinal anesthesia显示文摘 | Pan PM Huang CT Wei TT | 1998 | Reg Anesth Pain Med1998，23，1： | 1 |
| 13 | Growth of straight nanotubcs with a cobalt-nickel catalyst by chemical vapor deposition显示文摘 | Sun L F Mao J M Pan Z W ct al | 1999 | Applied Physics Letters1999，74，5： | 1 |
| 14 | Fabrication of gapless dual-curvature microlens as a diffuser for a LED package显示文摘 | CT Pan etc | 2009 | Sensors and Actuators2009，，： | 1 |
| 15 | Voltage constraint tracking based field weakening control of IPM synchronous motor drives显示文摘 | SUE SM PAN CT | 2008 | IEEE Transactions on Industrial Electronics2008，55，1： | 1 |
| 16 | Sensing characteristics of double layer film ofZnO 显示文摘 | Xu J Q Shun Y A Pan Q Y ct al | 2000 | Sensors and Actuators B2000，66，： | 1 |
| 17 | Drug therapy for ulcerative colitis显示文摘 | Xu CT Meng SY Pan BR | 2004 | World J Gastroenterol2004，10，： | 1 |
| 18 | New isoprenylated flavonoids and cytotoxic constituents from Artocarpus tonkinensis 显示文摘 | Ma J P Qiao X Pan S ct al | 2010 | J Asian Nat Prod Res2010，12，7： | 1 |
| 19 | Isolation and characterization of a variant porcine epidemic diarrhea virus in China显示文摘 | Pan Y Tian X Li W ct al | 2012 | Virol J2012，9，： | 1 |
| 20 | Effects of Astragalus polysaccharides(APS) on the expression of immune response genes in head kidney,gill and spleen of the common carp,Cyprinus carpio L显示文摘 | Yuan CT Pan XP Gong Y | 2008 | Interna Immunopharmacol2008，8，： | 1 |
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