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| 1 | Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing显示文摘AIM:To investigate the low gastric cancer incidence rate relative to the highly prevalent Helicobacter pylori(H.pylori)infection;data relevant to H.pylori infection during gastric carcinogenesis in Indian patients is currently lacking.METHODS:The present study examines the prevalence of H.pylori infection in DNA derived from 156endoscopic gastric biopsies of different disease groups that represent gastric pre-cancer[intestinal metaplasia(n=15),dysplasia(n=15)],cancer[diffuse adenocarcinoma(n=44),intestinal adenocarcinoma(n=21)],and symptomatic but histopathologically-normal controls(n=61).This was done by generic ureC polymerase chain reaction(PCR)and cagA-specific PCR that could specifically identify the carcinogenic H.pylori strain.RESULTS:Our analysis showed the presence of H.pylori infection in 61%of symptomatic histopathologically-normal individuals,however only 34%of control tissues were harboring the cagA+H.pylori strain.A similar proportion of H.pylori infection(52%)and cagA(26%)positivity was observed in the tumor tissue of the gastric cancer group.In comparison,H.pylori infection(90%)and cagA positivity(73%)were the highest in gastric pre-cancer lesions.In relation to tobacco and alcohol abuse,H.pylori infection showed an association with tobacco chewing,whereas we did not observe any association between tobacco smoking or alcohol abuse with prevalence of H.pylori infection in the tissue of any of the patient groups studied.CONCLUSION:High incidence of H.pylori infection and carcinogenic cagA positive strain in pre-cancer lesions during gastric carcinogenesis may be | Arvind Pandey Satyendra Chandra Tripathi Sutapa Mahata Kanchan Vishnoi Shirish Shukla Sri Prakash Misra Vatsala Misra Suresh Hedau Ravi Mehrotra Manisha DwivediZ Alok C Bharti | 2014 | World Journal of Gastroenterology2014，20，22： | 4 |
| 2 | Clinical evaluation of xylazine with barbiturate and non - barbitturate anesthesia in dogs显示文摘 | Pathak J C Pandey S S Sukla B P | 1998 | Indian Veterinary Journal1998，75，10： | 2 |
| 3 | Solid-state fermentation for the production of Monascus pigments from jackfruit seed 显示文摘 | Babitha S Soccol C R Pandey A | 2007 | Bioresouree Technology2007，98，8： | 1 |
| 4 | Multilayer perceptron in damage detection of bridge structures显示文摘 | Pandey P C Barai S V | 1995 | Computers & Structures1995，54，4： | 1 |
| 5 | Performance modeling of multistage production systems operating under hybrid push/pull control显示文摘 | Pandey P C Prontep Khokhajaikiat | 1996 | International Journal of Production Economics1996，43，1： | 1 |
| 6 | Nanoindentationstudy of magnetron-sputtered CrN and CrSiN coatings显示文摘 | Shah H N Jayaganthan R Pandey A C | | Materials and Design0，32，： | 1 |
| 7 | Endovascular coil embolization of ruptured and unruptured posterior circulation aneurysms:review of a 10-year expemrience显示文摘 | PANDEY A S KOEBBE C ROSENWASSER R H | 2007 | Neurosurgery2007，60，4： | 1 |
| 8 | Drought stress inducedchanges in lipid peroxidation and antioxidant system in genus avena显示文摘 | Pandey Harish C Baig M J Chandra A | 2010 | The Journal of Environmental Biology2010，31，4： | 1 |
| 9 | Production of flammulina velulipes on coffee husk and coffee spent-ground显示文摘 | Leifa F Pandey A Soccol C R | 2001 | Brazilian Archives of Biology and Technology2001，44，2： | 1 |
| 10 | Effect of heavy metals Co^2+ , Ni^2+ and Cd^2- on growth and metabolism of cabbage 显示文摘 | PANDEY N SHARMA C P | 2002 | Plant Science2002，163，4： | 1 |
| 11 | Solid-state fermentation for the production of Monascus pigments from jackfruit seed显示文摘 | BABITHA S SOCCOL C R PANDEY A | 2007 | Bioresource Technology2007，98，8： | 1 |
| 12 | Analysis and modeling of EDM parameters显示文摘 | Jilani S T Pandey P C | 1982 | Precision Engineering1982，4，4： | 1 |
| 13 | Identification of critical erosion prone areas in the small agricultural watershed using USLE, GIS and remote sensing 显示文摘 | A PANDEY V M CHOWDARY B C MAL | 2007 | Water Resources Management2007，21，4： | 1 |
| 14 | Two novel GPCR- type G proteins are abscisic acid receptors in Arabidopsis 显示文摘 | Pandey S Nelson D C Assmann S M | 2009 | Cell2009，136，1： | 1 |
| 15 | New development in solid state fermentation: l-bioprocess and products 显示文摘 | PANDEY A C R SOCCOL C R MITCHELL D | 2000 | Process Biochemistry2000，35，10： | 1 |
| 16 | A gradient method for computing the optimal H∞ norm 显示文摘 | Pandey P Kenney C Packare A | 1991 | IEEE T Automatic Control1991，36，7： | 1 |
| 17 | Thermochemical Model of a 2-Stage Smelting Reduction Process for Iron-Making显示文摘 | Koria S C Barui M K Pandey L K | 1999 | Scandinavian Journal of Metallurgy1999，28，11： | 1 |
| 18 | Runoffand sediment yield modeling from a small agriculturalwatershed in India using the WEPP model显示文摘 | PANDEY A CHOWDARY V M MAL B C | 2008 | Journal ofHydrology2008，348，34： | 1 |
| 19 | Recent advances in solid-state fermentation 显示文摘 | Singhania R R Patel A k Soccol C R Pandey A | 2009 | Biochem Eng J2009，44，： | 1 |
| 20 | 显示文摘 | Singh A P Singh P C Pandey K K | 1988 | Ind Eng Chem Res1988，27，9： | 1 |
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