维普中文期刊产品整合服务
102篇 您的检索式:作者名="Pasare"
    题名 作者 年代 出处 被引量
1Animal models of portal hypertension显示文摘Animal models have allowed detailed study of hemodynamic alterations typical of portal hypertension and the molecular mechanisms involved in abnormalities in splanchnic and systemic circulation associated with this syndrome. Models of prehepatic portal hypertension can be used to study alterations in the splanchnic circulation and the pathophysiology of the hyperdynamic circulation. Models of cirrhosis allow study of the alterations in intrahepatic microcirculation that lead to increased resistance to portal ? ow. This review summarizes the currently available literature on animal models of portal hypertension and analyzes their relative utility. The criteria for choosing a particular model, depending on the specific objectives of the study, are also discussed.Juan G Abraldes Marcos Pasarín Juan Carlos García-Pagán 2006World Journal of Gastroenterology2006,12,41:14
2Intrahepatic vascular changes in non-alcoholic fatty liver disease: potential role of insulin-resistance and endothelial dysfunction显示文摘Metabolic syndrome is a cluster of several clinical conditions characterized by insulin-resistance and high cardiovascular risk. Non-alcoholic fatty liver disease is the liver expression of the metabolic syndrome, and insulin resistance can be a frequent comorbidity in several chronic liver diseases, in particular hepatitis C virus infection and/or cirrhosis. Several studies have demonstrated that insulin action is not only relevant for glucose control, but also for vascular homeostasis. Insulin regulates nitric oxide production, which mediates to a large degree the vasodilating, antiinflammatory and antithrombotic properties of a healthy endothelium, guaranteeing organ perfusion. The effects of insulin on the liver microvasculature and the effects of IR on sinusoidal endothelial cells have been studied in animal models of non-alcoholic fatty liver disease. The hypotheses derived from these studies and the potential translation of these results into humans are critically discussed in this review.Marcos Pasarín Juan G Abraldes Eleonora Liguori Beverley Kok Vincenzo La Mura 2017World Journal of Gastroenterology2017,23,37:6
3Toll pathway- dependent blockade of CD4^+ CD25^+ T cell-mediated suppression by dendritic cells显示文摘Pasare C Medzhitov R 2003Science2003,299,:1
4Toll-like receptors: balancing host resistance with immune tolerance 显示文摘Pasare C Medzhitnv R 2003Curr Opin Immunol2003,15,6:1
5Toll pathway-dependent blockade of CD4 + CD25 + T cell-mediated suppression by dendritic cells 显示文摘PASARE C MEDZHITOV R 2003Science2003,299,5609:1
6Toil-like receptors: linking innate and adaptive immunity显示文摘Pasare C Medzhltov R 2004Microbes and Infection2004,6,15:1
7Toll-like receptors: linking innate and adaptive immunity 显示文摘Pasare C Medzhitov R 2004Microbes Infect2004,6,15:1
8Control of B-cell responses by Toll-like receptors 显示文摘Pasare C Medzhitov R 2005Natur2005,438,7066:1
9Toll-like receptors: linking innate and adaptive immunity显示文摘Pasare C Medzhitov R 2004Microbes Infect2004,6,15:1
10Toll-like receptors:linking innate and adaptive immunity 显示文摘Pasare C Medzhitov R 2005Adv Exp Med Biol2005,560,:1
11Toll pathway-dependent blockade of CD4 + CD25 +T cell-mediated suppression by dendritic cells 显示文摘Pasare C Medzhitov R 2003Science2003,299,5609:1
12Toll pathway-dependent blockade of CD4+CD25 + T cell-mediated suppression by dentritic cells 显示文摘Pasare C Medzhitov R 2003Science2003,299,5609:1
13Toll-like receptors:blancing host resistance with immune tolerance显示文摘Pasare C Medzhitov R 2003Curr Opin Immunol2003,15,6:1
14Toll-like receptors: balancing host resistance with immune tolerance显示文摘Pasare C Medzhitov R 2003Curr Opin Immuno12003,15,6:1
15Toll pathway dependent blockade of CD4 + CD25 + T cell-mediated suppression by dendritic cells 显示文摘Pasare C Medzhitov R 2003Science2003,299,5609:1
16Toll pathway-dependent blockade of CD4^+ CD25^+ T cell-mediated suppression by dendritic cells显示文摘Pasare C Medzhitov R 2003Science2003,299,5609:1
17Toll pathway-dependent blockade of CD4^+CD25^+ T cell-mediated suppe ression by dendritic cells显示文摘Pasare C Medzhitov R 2003Science2003,299,5624:1
18Toll pathway-dependent blockadeof CD4 + CD25 + T cell-mediated suppression by dendriticcells显示文摘Pasare C Medzhitov R 2003Science2003,299,5609:1
19Toll pathway-dependent blockade of CD4+CD25+T cell-mediated suppression by dendriticcells 显示文摘Pasare C Medzhitov R 2003Selene e2003,299,5609:1
20Toll-like receptors:balancing host resistance with immune tolerance显示文摘Pasare C Medzhitov R 2003Curr Opin Immunol2003,15,6:1
返回顶部 每页显示:
共6页 首页 上一页 第1页 下一页 末页 /6 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费