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63篇 您的检索式:作者名="Patial"
    题名 作者 年代 出处 被引量
1Peroxisome proliferator-activated receptor gamma as a therapeutic target for hepatocellular carcinoma:Experimental and clinical scenarios显示文摘Hepatocellular carcinoma(HCC)is the most common type of liver cancer worldwide.Viral hepatitis is a significant risk factor for HCC,although metabolic syndrome and diabetes are more frequently associated with the HCC.With increasing prevalence,there is expected to be>1 million cases annually by 2025.Therefore,there is an urgent need to establish potential therapeutic targets to cure this disease.Peroxisome-proliferator-activated receptor gamma(PPARγ)is a ligand-activated transcription factor that plays a crucial role in the pathophysiology of HCC.Many synthetic agonists of PPARγsuppress HCC in experimental studies and clinical trials.These synthetic agonists have shown promising results by inducing cell cycle arrest and apoptosis in HCC cells and preventing the invasion and metastasis of HCC.However,some synthetic agonists also pose severe side effects in addition to their therapeutic efficacy.Thus natural PPARγagonists can be an alternative to exploit this potential target for HCC treatment.In this review,the regulatory role of PPARγin the pathogenesis of HCC is elucidated.Furthermore,the experimental and clinical scenario of both synthetic and natural PPARγagonists against HCC is discussed.Most of the available literature advocates PPARγas a potential therapeutic target for the treatment of HCC.Swati Katoch Vinesh Sharma Vikram Patial 2022World Journal of Gastroenterology2022,28,28:2
2Acute fatal paraquat poisoning 显示文摘Patial RK 2003J Assoc Physicians India2003,51,:1
3Role of acidity for the production of earvaerol from earvone over surfated zircona显示文摘SINGH B PATIAL J SHARMA P 2011Indian journal of chemical teehnology2011,,18:1
4Acute fatal paraquat poisoning显示文摘Patial RK 2003J Assoc Physicians India2003,51,:1
5Acute fatal paraquat poisoning显示文摘Patial RK 2003J Assoc Physicians India2003,51,:1
6Acute fatal paraquat poisoning显示文摘Patial RK 2003J Assoc Physicians India2003,51,1:1
7Tumor Necrosis Factor- α Signaling in Macrophages 显示文摘Narayanan Parameswaran Sonika Patial 2010Critical Reviews in Eukaryotic Gene Expression2010,20,2:1
8Acute fatal paraquat poisoning 显示文摘Patial RK 2003J Assoc Physicians India2003,51,:1
9Influence of acidity, of montmorillonite and modified montmorillonite clay minerals for the conversion of longifolene to isolongifolene显示文摘B Singh J Patial P Sharma 2006Journal of Molecular Catalysis A: Chemical2006,266,:1
10Virus neutralizing antibodyresponse in mice and dogs with a bicistronic DNA vaccineencoding rabies virus glycoprotein and canine parvovirus VP2显示文摘Patial S Chaturvedi VK Rai A 2007Vaccine2007,25,20:1
11G-protein-coupled receptor kinases mediate TNFα-indueed NFKB signalling via direct interaction with and phosphorylation of IKBα 显示文摘Patial S Luo J Porter KJ 2010Biochem J2010,425,1:1
12Acute fatal paraquat poisoning 显示文摘Patial R K 2003J Assoc Physicians India2003,51,:1
13Acute fatal paraquat poisoning 显示文摘Patial RK 2003J Assoc Physicians India2003,51,:1
14Acute fatal paraquat poisoning显示文摘Patial R K 2003J Assoc phy- sicians India2003,51,:1
15Cationic imidazolium monomeric surfactants: their synthesis and surface active properties显示文摘AHMAD I PATIAL P KAUR C 2014J Surfactants Deterg2014,17,2:1
16Virus neutralizing anti- body response in mice and dogs with a bicistronic DNA vaccine encoding rabies virus glycoprotein and canine parvovirus VP2 显示文摘Patial S Chaturvedi V K Rai A 2007Vaccine2007,25,20:1
17Tumor Necrosis Factor- αSignaling in Macrophages 显示文摘P N Patial S 2010Crit Rev Eukaryot Gene Expr2010,20,2:1
18G-protein coupled receptor ki-nase 5 mediates lipopolysaccharide-induced NF-jcB activation inprimary macrophages and modulates inflammation in vivo in mice显示文摘Patial S Shahi S Saini Y 2011J Cell Physiol2011,226,5:1
19Acute fatal paraquat poisoning显示文摘Patial RK 2003J Assoc Physi- cians India2003,51,5:1
20G-protein-coupled-receptor ki-nases mediate TNF a-induced NF-kB signalling via direct interac-tion with and phosphorylation of I/cBa显示文摘Patial S Luo J Porter K J 2010Biochem J2010,425,1:1
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