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| 1 | Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart显示文摘出生后的心通过 hypertrophic 生长适应应力和超载,可能病理学或有益的一个过程(生理的肥大) 。生理的肥大改进心脏的性能在健康并且 diseased 个人,然而,宣传这有利改编的机制仍然保持糟糕定义。我们识别 cytokine cardiotrophin (CT1 ) 1 作为能够包括导致的导出 cardiomyocyte 的 angiogenic 信号的心肌层,和刺激的短暂、可逆的肥大概括心的生理的生长的特色的一个因素增加了由脉管形成。CT1 的能力从 caspase 激活的调停 CK2 的制止发源导致生理的肥大,阻止到无限制的病理学的生长的转变。外长的 CT1 蛋白质交货稀释了病理并且在正确的心失败的一个严格的模型恢复了可收缩的功能,建议为这难处理的心脏病的一种新奇处理选择。 | Mohammad Abdul-Ghani Colin Suen Baohua Jiang Yupu Deng Jonathan J Weldrick Charis Putinski Steve Brunette Pasan Femando Tom T Lee Peter Flynn Frans H H Leenen Patrick G Burgon Duncan J Stewar Lynn A Megeney | 2017 | Cell Research2017,27,10: | 8 |
| 2 | COX-2 polymorphisms-765G→C and-1195A→G and colorectal cancer risk显示文摘AIM:To determine the possible modulating effect of the COX-2 polymorphisms,-765G→C and-1195A→G, on the risk of colorectal cancer(CRC)in a Dutch population. METHODS:This case-control study includes 326 patients with CRC and 369 age-and gender-matched controls.Genotypes of the COX-2 polymorphisms -765G→C and-1195A→G were determined by polymerase chain reaction-based restriction fragment length polymorphism.COX-2 genotypes and haplotypes were analyzed and odds ratios with 95%confi- dence intervals were estimated by logistic regression. RESULTS:The-765GG genotype was associated with an increased risk of developing CRC(OR,1.45; 95%CI,1.03-2.04).No significant difference was observed in the genotype distribution of the-1195A→ G polymorphism between patients and controls.The GG/AC haplotype was present significantly less often in patients than in controls(OR 0.44;95%CI,0.22-0.85). When the AC,AG and GG haplotypes were investigated separately,the AC haplotype showed a tendency to be less frequent in patients than in controls(OR(AG/AC)0.78; 95%CI,0.57-1.06). CONCLUSION:The-765GG genotype is associatedwith an increased risk of developing CRC and the GG/ AC haplotype seems to protect against CRC.These findings suggest a modulating role for the COX-2 polymorphisms-765G→C and-1195A→G in the development of CRC in a Dutch population. | Juliёt H Hoff Rene HM te Morsche Hennie MJ Roelofs Elise MJ van der Logt Fokko M Nagengast Wilbert HM Peters | 2009 | World Journal of Gastroenterology2009,15,36: | 6 |
| 3 | Variations in Wool Growth with Nutrient Supply in Northern China显示文摘Field studies on essessment of nutritional status of the grazing sheep were carried out in each of the three major grassland regions, the eastern Inner Mongolia and beyond grassland, the Inner Mongolia - Ningxia - Gansu grassland and the Xinjiang grassland, in northern China. The results obtained showed that the wool production of fine wool sheep in these regions varied between regions and seasons, with similar seasonal patterns in all regions and that reducing the seasonal variations in nutrient supply would enhance wool production substantially. Nutritional limitations to wool growth of the grazing sheep in these regions were suggested, those were: the shortage of protein supply in winter and early spring; the poor quality of much of the pasture and the hay used as supplements, the low energy intake during winter which probably necessitated the use of body stores to maintain body temperature. | D X Lu,Iner(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)Z C Feng,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)H R Wang,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)R Z Yang,(Xinjiang Institute of Animal Science.Xinjiang Academy of Animal Science.Yiu Hou Road.Urumqi.Xinjiang Uygur Autonomous Region PRC)C T Ma,(Chinese Academy of Agricultural Sciences.Lanzhou.Gansu.PRC)D B Purser,(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)J R Lindsay(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)D W Peter(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014) | 1997 | 畜牧与饲料科学1997,22,S1: | 3 |
| 4 | Racial differences in effectiveness of α-fetoprotein for diagnosis of hepatocellular carcinoma in hepatitis C virus cirrhosis显示文摘 | Mindie H Nguyen Ruel T Garcia Peter W Simpson Teresa L Wright Emmet B Keeffe | 2002 | Hepatology2002,,2: | 2 |
| 5 | Severe valproic acid intoxication is associated with atrial tachycardia: secondary detoxication by hemoperfusion 显示文摘 | MEYER S KUHLMANN M K PETERS F T LIMBACH H G LINDINGER A | 2005 | Klin Padiatr2005,217,2: | 1 |
| 6 | Langerhans cells utilize CDla and langerin to efficiently present nonpeptide antigens to T cells显示文摘 | Robert E H Peter A S Maria T | 2004 | J Clin Invest2004,113,5: | 1 |
| 7 | RolEnact:role-basedenactable models of business processes显示文摘 | KEITH T PETER H ROBERT J | 1998 | Information and Soft-ware Technology1998,40,3: | 1 |
| 8 | Pharmacological significance of an enteric- coated formulation of garlic powder显示文摘 | GLEITZ J PETERS T H | 1995 | Medizinische Welt1995,46,: | 1 |
| 9 | New equations for omnidirec- tional sonic temperature variance and buoyancy heat flux with a sonic anemometer显示文摘 | Liu H P Peters G Foken T | 2011 | Bound-Layer Meteor2011,100,: | 1 |
| 10 | Towards an Intemational Classif- ication for Patient Safety: key concepts and terms 显示文摘 | William R Peter H Richard T | 2009 | International Journal for Quality in Health Care2009,21,1: | 1 |
| 11 | Primary malignant mixed mullerian tumor of the uterus: findings on sonography, CT, and gadolinium-enhanced MRI 显示文摘 | TEO S Y BABAGBEMI K T PETERS H E | 2008 | AJR2008,191,1: | 1 |
| 12 | Geochemistry of crude oils from eastern Indonesia显示文摘 | Peters K E Fraser T H Amris W | 1999 | American Association of Petroleum Geologists Bulletin1999,83,12: | 1 |
| 13 | A physical concept of soil-water equilibria for nonionic organic compounds 显示文摘 | CHIOU C T PETERS L J FREED V H | 1979 | Science1979,206,16: | 1 |
| 14 | Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma显示文摘 | Matthias L?hr Anne Hoffmeyer Jens-Christian Kr?ger Mathias Freund Johannes Hain Albrecht Holle Peter Karle Wolfram T Kn?fel Stefan Liebe Petra Müller Horst Nizze Matthias Renner Robert M Saller Thomas Wagner Karlheinz Hauenstein Walter H Günzburg Brian Sa | 2001 | The Lancet2001,,9268: | 1 |
| 15 | Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes metabolism and hormonal regulation显示文摘 | William G H Lorie C P | 1990 | Journal of Nutrition1990,120,: | 1 |
| 16 | A physical concept of soil water equilibria for nouionic organic compounds 显示文摘 | Chiou C T Peters L J Freed V H | 1979 | Science1979,206,: | 1 |
| 17 | Vascular plant diversity in natural and anthropogenic ecosystems in the Andes of southern Ecuador studies from the Rio San Francisco valley显示文摘 | PETERS T DIERTL K H GAWLIK J | 2010 | Mountain Research and Development2010,30,4: | 1 |
| 18 | A physical concept of soil-water equilibria for nonionic organic compounds显示文摘 | Chiou C T Peter L J Fred V H | 1979 | Science1979,206,: | 1 |
| 19 | Successful percutaneous coronary intervention with stent implantation in anomalous right coronary arteries arising from the left sinus of valsalva:a report of two cases显示文摘 | COHEN M G TOLLESON T R PETER R H | 2002 | Catheter Cardiovasc Interv2002,55,: | 1 |
| 20 | New equations for sonic temperature variance and buoyancy heat flux with an omnidirectional sonic anemometer 显示文摘 | Liu H Peters G Foken T | 2001 | Boundary-Layer Meteorology2001,100,: | 1 |