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| 1 | 英国胃肠病学会关于胃癌风险患者的诊断和管理指南显示文摘胃癌预后较差,部分原因在于诊断较晚。胃癌的危险因素包括幽门螺杆菌(H.pylori,HP)感染和胃癌家族史,尤其是遗传性弥漫性胃癌和恶性贫血。胃癌发展的阶段包括慢性胃炎、胃黏膜萎缩(GA)、胃黏膜肠化生(GIM)和异型增生。胃癌早期发现和提高生存率的关键是在内镜检查前以非侵入性方式识别高危人群。然而,尽管生物标志物可能有助于检测慢性萎缩性胃炎,但尚无足够的证据支持其用于人群筛查。高质量内镜检查是胃癌早期发现的重要组成部分,图像增强内镜结合组织病理学活检是GA和GIM最佳的诊断方法,并能准确进行风险分层。按照悉尼标准从胃窦、角切迹、小弯和大弯进行活检,既能明确诊断,也能对胃癌进行风险分层。理想状态应当是在高质量内镜检查中对GA或GIM区域活检。英国属于低危地区,可根据需要接受常规诊断性胃镜检查,但没有足够证据支持筛查,对于广泛GA或GIM的患者,每3年检查内镜。对于胃异型增生和早期癌,只要满足标准,内镜下黏膜切除术或内镜黏膜下剥离术的治疗有效,成功率高,复发率低。 | Matthew Banks David Graham Marnix Jansen TakujiGotoda Sergio Coda Massimiliano di Pietro NoriyaUedo Pradeep Bhandari D Mark Pritchard Ernst J Kuipers Manuel Rodriguez-Justo Marco R Novelli KrishRagunath Neil Shepherd Mario Dinis-Ribeiro 乌雅罕(译) 张冬雪(译) 牛占岳(校) 刘鑫(校) 丁士刚(译/校) | 2020 | 中华胃肠内镜电子杂志2020，7，2： | 10 |
| 2 | 尼泊尔喜马拉雅山冰川分布特征显示文摘在中段喜马拉雅山南坡的尼泊尔境内,利用尼泊尔两次编目数据、2009—2010年Landsat遥感影像及数字高程模型,得到最新尼泊尔喜马拉雅山冰川分布图.利用GIS和统计软件分析了该地区冰川的空间分布、规模、类型特征.结果如下:水平方向上,冰川面积在经度上呈波状分布;垂直方向上,最大面积高度及对应的最大面积值分布流域从大到小是Gandaki、Koshi、Karnali流域.冰川面积在垂直空间的集中性与冰川作用差呈负相关;各流域发育小型冰川的条数较多,中型冰川的面积较多.大型冰川对地势和降水条件要求高,只分布在尼泊尔中部和东部;形态类型以复式流域、复式盆地和单一盆地为主,表碛覆盖冰川和雪崩补给冰川分布普遍. | 殷俊琦 谢自楚 吴立宗 MOOL K PRADEEP BAJRACHARYA R SAMJWAL | 2012 | 湖南师范大学自然科学学报2012，35，3： | 3 |
| 3 | Optoelectronic properties and Seebeck coefficient in SnSe thin films显示文摘SnSe thin films of thickness 180 nm have been deposited on glass substrates by reactive evaporation at an optimized substrate temperature of 523 ± 5 K and pressure of 10^(-5) mbar.The as-prepared SnSe thin films are characterized for their structural,optical and electrical properties by various experimental techniques.The p-type conductivity,near-optimum direct band gap,high absorption coefficient and good photosensitivity of the SnSe thin film indicate its suitability for photovoltaic applications.The optical constants,loss factor,quality factor and optical conductivity of the films are evaluated.The results of Hall and thermoelectric power measurements are correlated to determine the density of states,Fermi energy and effective mass of carriers and are obtained as 2.8×10^(17)cm^(-3),0.03 eV and 0.05m_0 respectively.The high Seebeck coefficient ≈ 7863 μV/K,reasonably good power factor ≈7.2×10^(-4) W/(m·K^2) and thermoelectric figure of merit ≈1.2 observed at 42 K suggests that,on further work,the prepared SnSe thin films can also be considered as a possible candidate for cryogenic thermoelectric applications. | K S Urmila T A Namitha J Rajani R R Philip B Pradeep | 2016 | Journal of Semiconductors2016，37，9： | 2 |
| 4 | Generalized structure of a multilevel PWM inverter显示文摘 | Pradeep M Bhagwat V R Stefanovic | | 0，，06： | 1 |
| 5 | Clinical effectiveness of au tologous platelet rich plasma and Peptide enhanced bone graft in the treatment of intrabony defects显示文摘 | Pradeep A R Shetty S K Garg G | 2009 | J Periodontol2009，80，1： | 1 |
| 6 | Use of hot EGR for NOx control in a com- pression ignition engine fuelled with bio- diesel from Jatropha oil 显示文摘 | Pradeep V Sharma R P | 2007 | Renewable Energy2007，32，： | 1 |
| 7 | Modeling ductal carcinoma in situ: a HER2-Notch3 collaboration enables luminal filling显示文摘 | Pradeep C R Kstler W J Lauriola M | 2012 | Oncogene2012，31，7： | 1 |
| 8 | Gingivalcrevicular fluid VEGF levels in periodontal health and dis-ease显示文摘 | Prapulla D V Sujatha P B Pradeep A R ei al | 2007 | J Periodontol2007，，： | 1 |
| 9 | Use of HOT EGR for NOx control in a compression ignition engine fuelled with bio-diesel from Jatropha oil显示文摘 | Pradeep V Sharma R P | | 0，，07： | 1 |
| 10 | Treatment of 3-Wall Intrahony Defects in Chronic Periodontitis Subjects With Autologous Platelet Rich Fi- brin A Randomized Controlled Clinical Trial 显示文摘 | Sharma A Pradeep A R | 2011 | J Periodontol2011，82，12： | 1 |
| 11 | Early carcinoma of the gallbladder : an elusive disease 显示文摘 | Kapoor VK pradeep R Haribhakti SP | 1996 | Journal of surgical Oncology1996，62，： | 1 |
| 12 | Effect of piperine on the inhibition of lung metastasis induced by B16F-10 melanoma cells in mice显示文摘 | PRADEEP C R KUTTAN G | 2002 | Clinical Experimental Metastasis2002，19，： | 1 |
| 13 | Clinical effect of autologous platelet- rich fibrin in the treatment of intra-bony defects: a controlled clinical trial 显示文摘 | Thorat M Pradeep A R Pallavi B | 2011 | J Clin Periodontol2011，38，10： | 1 |
| 14 | Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in tumor angiogenesis and malignancies显示文摘 | Pradeep C R Sunila E S Kuttan G | 2005 | Integr Cancer Ther2005，4，4： | 1 |
| 15 | Embracing Dynamic Evolution in Distributed Systems显示文摘 | Fung K H Graham L Pradeep K R | 2004 | IEEE Software2004，21，2： | 1 |
| 16 | Effect of low-cost storage andpackaging on quality and nutritive value of fresh and dehydratedcarrot显示文摘 | Pradeep S N Susanta K R | 2000 | Journal of the Science of Food and Agriculture2000，，80： | 1 |
| 17 | Association of progranulin and high sensitivity CRP concentrations in gingival crevicular fluid and serum in chronic periodontitis subjects with and without obesity显示文摘 | Pradeep A R Priyanka N Prasad M V | 2012 | Dis Markers2012，33，4： | 1 |
| 18 | Hypoxia-me- diated downregulation of miRNA biogenesis promotes tumour progression 显示文摘 | RUPAIMOOLE R WU S Y PRADEEP S | 2014 | Nat Commun2014，5，： | 1 |
| 19 | Semi-preparative isolation and structural elucidation of an impurity in citalopram by LC/MS/MS显示文摘 | BHANU R BRAJESH A S PRADEEP D G | 2009 | J Pharm Biomed Anal2009，50，： | 1 |
| 20 | Controlled porosity osmotic pump-based controlled release systems of pseudoephedrine显示文摘 | Sapna N Makhija Pradeep R Vavia | 2003 | Journal of Controlled Release2003，，1： | 1 |
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