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| 1 | Inuence of oxytetracycline on the structure and activity of microbial community in wheat rhizosphere soil显示文摘The microbial community composition in wheat rhizosphere was analyzed by detecting colony forming units (CFUs) in agar plates. The total CFUs in rhizosphere were 1.04 × 109/g soil with 9.0 × 108/g bacteria, 1.37 × 108/g actinomyces and 3.6 × 106/g fungi. The 10 dominant bacteria were isolated from wheat rhizosphere and were grouped into genus Bacillus according to their full length 16S rRNA gene sequences. Although belonging to the same genus, the isolated strains exhibited dierent sensitivities to oxytetracycline. When a series of the rhizosphere soil was exposed under various concentrations of oxytetracycline, the microbial community structure was highly aected with significant decline of CFUs of bacteria and actinomyces (22.2% and 31.7% at 10 mg/kg antibiotic, respectively). This inhibition was clearly enhanced with the increase exposure dosage of antibiotic and could not be eliminated during 30 d incubation. There was no obvious inuence of this treatment on fungi population. Among the four soil enzymes (alkaline phosphatase, acidic phosphatase, dehydrogenase and urease), only alkaline phosphatase was sensitive to oxytetracycline exposure with 41.3% decline of the enzyme activity at 10 mg/kg antibiotic and further decrease of 64.3%-80.8% when the dosage over 30 mg/kg. | YANG Qingxiang, ZHANG Jing, ZHU Kongfang, ZHANG Hao College of Life Sciences, Henan Normal University, Xinxiang 453007, China. | 2009 | Journal of Environmental Sciences2009，21，7： | 36 |
| 2 | Assessment of the uncertainties in temperature change in China during the last century显示文摘We have used the China Homogenized Historic Temperature dataset and some long-term station series of the neighbor countries from CRUTEM3,a 5°×5° gridded dataset of monthly mean temperature since 1900,to provide a 107-year record of surface temperature trends and variability.We derived a comprehensive set of uncertainty estimates to accompany the data:measurement and sampling errors,uncertainties in temperature bias estimates,and uncertainties arising from limited observational coverage on large-scale averages have all been estimated.We reanalysed the temperature changes during the period of record.The best estimates of trends for 1900-2006 with uncertainties at 95% confidence range are about 0.09±0.017°C/decade for the year as a whole,and 0.14±0.021°C/decade,0.11±0.021°C/decade,0.04±0.017°C/decade,and 0.07±0.017°C/decade for winter,spring,summer and autumn respectively.For 1954-2006,the trends for annual,winter,spring,summer and autumn are:0.26±0.032°C/decade,0.35±0.046°C/decade,0.25±0.051°C/decade,0.16±0.037°C/decade and 0.22±0.055°C/decade.Winter saw the most significant warming trend in both 1900-2006 and 1954-2006,while during the most recent period(the satellite era,1979-2006),all the seasons show similar warming trends:0.45±0.13°C/decade,0.51±0.11°C/decade,0.52±0.16°C/decade,0.37±0.10°C/decade and 0.50±0.16°C/decade for annual,winter,spring,summer and autumn.Trends arising from urbanization have been evaluated as less than 5% of the total warming trend for 1951-2001,so this bias was not removed. | LI QingXiang DONG WenJie LI Wei GAO XiaoRong JONES P KENNEDY J PARKER D | 2010 | Chinese Science Bulletin2010，55，19： | 26 |
| 3 | Effect of Saccharomyces cerevisiae on alfalfa nutrient degradation characteristics and rumen microbial populations of steers fed diets with different concentrate-to-forage ratios显示文摘Live yeast(Saccharomyces cerevisiae) constitutes an effective additive for animal production;its probiotic effect may be related to the concentrate-to-forage ratio(CTFR).The objective of this study was to assess the effects of S.cerevisiae(SC) on fiber degradation and rumen microbial populations in steers fed diets with different levels of dietary concentrate.Ten Simmental × Local crossbred steers(450 ± 50 kg BW) were assigned to a control group or an SC group.Both groups were fed the same basal diet but the SC group received SC supplementation(8 × 10~9 cfu/h/d through the ruminal fistula)following a two-period crossover design.Each period consisted of four phases,each of which lasted 17 d:10 d for dietary adaptation,6 d for degradation study,and 1 d for rumen sample collection.From the 1^(st) to the 4^(th) phase,steers were fed in a stepwise fashion with increasing CTFRs,i.e.,30:70,50:50,70:30,and 90:10.The kinetics of dry matter and fiber degradation of alfalfa pellets were evaluated;the rumen microbial populations were detected using real-time PCR.The results revealed no significant(P> 0.05) interactions between dietary CTFR and SC for most parameters.Dietary CTFR had a significant effect(P< 0.01) on degradation characteristics of alfalfa pellets and the copies of rumen microorganism;the increasing concentrate level resulted in linear,quadratic or cubic variation trend for these parameters.SC supplementation significantly(P< 0.05) affected dry matter(DM) and neutral detergent fiber(NDF)degradation rates(c_(DM),c_(NDF)) and NDF effective degradability(ED_(NDF)).Compared with the control group,there was an increasing trend of rumen fungi and protozoa in SC group(P < 0.1);copies of total bacteria in SC group were significantly higher(P< 0.05).Additionally,percentage of Ruminobacter amylophilus was significantly lower(P< 0.05)but percentage of Selenomonas ruminantium was significantly higher(P< 0.05) in the SC group.In a word,dietary CTFR had a significant effect on degradation characteristics of forage and rumen microbial population.S.cerevisiae had positive effects on DM and NDF degradation rate or effective degradability of forage;S.cerevisiae increased rumen total bacteria,fungi,protozoa,and lactate-utilizing bacteria but reduced starch-degrading and lactate-producing bacteria. | Gengzhi Ding Ying Chang Liping Zhao Zhenming Zhou Liping Ren Qingxiang Meng | 2014 | Journal of Animal Science and Biotechnology2014，5，4： | 15 |
| 4 | A comparison of the energy consumption and carbon emissions for different modes of transportation in open-cut coal mines显示文摘Transportation accounts for 80% of open-cut coal mine carbon emissions.With regard to the energy consumption and carbon emissions of transportation within an open-cut mine,this paper systematically compared the work and energy consumption of a truck and belt conveyor on a theoretical basis,and constructed a model to calculate the energy consumption of open-cut mine transportation.Life cycle carbon emission factors and power consumption calculation model were established through a Process Analysis–Life Cycle Analysis(PA–LCA).The following results were obtained:(1) the energy consumption of truck transportation was four to twelve times higher than that of the belt conveyor;(2) the CO2 emissions from truck transportation were three to ten times higher than those of the belt conveyor;(3) with the increase in the slope angle for transportation,the ratio of truck to belt conveyor for both energy consumption and carbon emissions gradually decreased;(4) based on 2013 prices in China,the energy cost of transportation using a belt conveyor in open-cut coal mines could save 0.6–2.4 Yuan/(t km) compared to truck transportation. | Liu Fuming Cai Qingxiang Chen Shuzhao Zhou Wei | 2015 | International Journal of Mining Science and Technology2015，25，2： | 12 |
| 5 | Zonal extraction technology and numerical simulation analysis in open pit coal mine显示文摘In order to enhance coal recovery ratio of open pit coal mines,a new extraction method called zonal mining system for residual coal around the end-walls is presented.The mining system can improve economic benefits by exploiting haulage and ventilation roadways from the exposed position of coal seams by utilizing the existing transportation systems.Moreover,the main mining parameters have also been discussed.The outcome shows that the load on coal seam roof is about 0.307 MPa and the drop step of the coal seam roof about 20.3 m when the thickness of cover and average volume weight are about 120 m and 0.023 MN/m 3 respectively.With the increase of mining height and width,the coal recovery ratio can be improved.However,when recovery ratio is more than 0.85,the average stress on the coal pillar will increase tempestuously,so the recovery ratio should also be controlled to make the coal seam roof safe.Based on the numerical simulation results,it is concluded that the ratio of coal pillar width to height should be more than 1.0 to make sure the coal pillars are steady,and there are only minor displacements on the end-walls. | Chen Yanlong Cai Qingxiang Shang Tao Peng Hongge Zhou Wei Chen Shuzhao | 2012 | International Journal of Mining Science and Technology2012，22，4： | 11 |
| 6 | Development of China homogenized monthly precipitation dataset during 1900-2009显示文摘Based on the collection and processing of the China national-wide monthly station observational precipitation data in 1900-2009,the data series for each station has been tested for their homogeneity with the Standard Normalized Homogeneity Test(SNHT) method and the inhomogeneous parts of the series are adjusted or corrected.Based on the data,the precipitation anomalies during 1900-2009 and the climatology normals during 1971-2000 have been transformed into the grid boxes at 5°×5° and 2°×2° resolutions respectively.And two grid form datasets are constructed by combining the normal and anomalies.After that,the missing values for the 5°×5° grid dataset are interpolated by Empirical Orthogonal Function(EOF) techniques.With the datasets of different resolutions,the precipitation change series during 1900-2009 over China's Mainland are built,and the annual and seasonal precipitation trends for the recent 110 years are analyzed.The result indicates that the annual precipitation shows a slight dryer trend during the past 110 years,notwithstanding lack of statistical confidence.It is worth noting that after the interpolation of the missing values,the annual precipitation amounts in the early 1900s become less,which increases the changing trend of the annual precipitation in China for the whole 110 years slightly(from-7.48 mm/100a to-6.48 mm/100a). | LI Qingxiang PENG Jiadong SHEN Yan | 2012 | Journal of Geographical Sciences2012，22，4： | 11 |
| 7 | A New Method for Quality Control of Chinese Rawinsonde Wind Observations显示文摘In 2006, the National Meteorological Information Center(NMIC) of the China Meteorological Administration(CMA)developed its real-time quality control(QC) system of rawinsonde observations coming from the Global Telecommunications System(GTS) and established the Global Upper-air Report Dataset, which, with the NMIC B01 format, is generally referred to as the B01 dataset and updated on a daily basis. However, when the B01 dataset is applied in climate analysis, some wind errors as well as some accurate values with incorrect error marks are found. To improve the quality and usefulness of Chinese rawinsonde wind observations, a new QC method(NewQC) is proposed in this paper. Different from the QC approach used for B01 datasets, the NewQC includes two vertical-wind-shear checks to analyze the vertical consistency of winds, in which the constant height level winds are used as reference data for the QC of mandatory pressure level winds. Different threshold values are adopted in the wind shear checks for different stations and different vertical levels. Several typical examples of QC of different error types by the new algorithm are shown and its performance with respect to 1980–2008 observational data is statistically evaluated. Compared with the radiosonde QC algorithms used in both the Meteorological Assimilation Data Ingest System(MADIS, http://gffzz1938ac3c542049bahwvqbo05bcbv56kpx.ffgz.tsg.suse.edu.cn/madis raob qc.html) of the National Oceanic and Atmospheric Administration(NOAA) and the B01 dataset, the NewQC shows higher accuracy and better reliability, particularly when used to judge successive observation errors. | LIAO Jie WANG Bin LI Qingxiang | 2014 | Advances in Atmospheric Sciences2014，31，6： | 10 |
| 8 | Global land-surface air temperature change based on the new CMA GLSAT data set显示文摘The China Meteorological Administration(CMA)has recently developed a new global monthly homogenized land-surface air temperature data set.Based on this data set,we reanalyzed the change in global annual mean land-surface air temperature(LSAT)during three time periods(1901–2014,1979–2014 and 1998–2014).The results show that the linear trends of global annual mean LSAT were 0.104°C/decade,0.247°C/decade and 0.098°C/decade for the three periods,respectively.The trends were statistically significant except for the period 1998–2014,the period that | Xiubao Sun Guoyu Ren Wenhui Xu Qingxiang Li Yuyu Ren | 2017 | Science Bulletin2017，62，4： | 10 |
| 9 | Experimental research of overburden movement and subsurface water seeping in shallow seam mining显示文摘Shallow seam coal field has the largest coal reserve in China. Mining in shallow depth causes serious problems, and sub- surface dewatering is a major issue. In this paper, the physical simulating models were prepared to study overburden movement and aquiclude stability in the shallow seam mining of Yushuwan Coalfield, China. According to the characteristic of clay aquiclude and bedrock in the overburden, the proper simulation materials for simulating the plastic clay aquiclude layers and brittle bedrock layers were determined by the stress-strain tests and hydrophilic tests. The physical simulating models of solid medium and two phases of solid-liquid medium were carried out to simulate the failure and caving process of the roof and overburden, as well as the subsurface water seeping. Based on the simulation, it was found that the movement of clay aquiclude follows the movement of the underlying bedrock layers. The stability of aquiclude is mainly affected by cracks in fracture zone. The tests also showed that the best way to control the stability of aquiclude is to reduce the subsiding gradient, and there is a possibility of ground water conservation under longwall mining in Yushuwan Mine. This research provides a foundation for further study on mining dewatering and water conserva- tion. | Qingxiang Huang | 2007 | Journal of University of Science and Technology Beijing2007，14，6： | 10 |
| 10 | Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer显示文摘To flourish,cancers greatly depend on their surrounding tumor microenvironment(TME),and cancer-associated fibroblasts(CAFs)in TME are critical for cancer occurrence and progression because of their versatile roles in extracellular matrix remodeling,maintenance of sternness,blood vessel formation,modulation of tumor metabolism,immune response,and promotion of cancer cell proliferation,migration,invasion,and therapeutic resistance.CAFs are highly heterogeneous stromal cells and their crosstalk with cancer cells is mediated by a complex and intricate signaling network consisting of transforming growth factor-beta,phosphoinositide 3-kinase/AKT/mammalian target of rapamycin,mitogen-activated protein kinase,Wnt,Janus kinase/signal transducers and activators of transcription,epidermal growth factor receptor,Hippo,and nuclear factor kappa-light-chain-enhancer of activated B cells,etc.,signaling pathways.These signals in CAFs exhibit their own special characteristics during the cancer progression and have the potential to be targeted for anticancer therapy.Therefore,a comprehensive understanding of these signaling cascades in interactions between cancer cells and CAFs is necessary to fully realize the pivotal roles of CAFs in cancers.Herein,in this review,we will summarize the enormous amounts of findings on the signals mediating crosstalk of CAFs with cancer cells and its related targets or trials.Further,we hypothesize three potential targeting strategies,including,namely,epithelial-mesenchymal common targets,sequential target perturbation,and crosstalk-directed signaling targets,paving the way for CAF-directed or host cell-directed antitumor therapy. | Fanglong Wu Jin Yang Junjiang Liu Ye Wang Jingtian Mu Qingxiang Zeng Shuzhi Deng Hongmei Zhou | 2021 | Signal Transduction and Targeted Therapy2021，6，7： | 9 |
| 11 | The Assessment of Global Surface Temperature Change from 1850s:The C-LSAT2.0 Ensemble and the CMST-Interim Datasets显示文摘Based on C-LSAT2.0,using high-and low-frequency components reconstruction methods,combined with observation constraint masking,a reconstructed C-LSAT2.0 with 756 ensemble members from the 1850s to 2018 has been developed.These ensemble versions have been merged with the ERSSTv5 ensemble dataset,and an upgraded version of the CMSTInterim dataset with 5°×5°resolution has been developed.The CMST-Interim dataset has significantly improved the coverage rate of global surface temperature data.After reconstruction,the data coverage before 1950 increased from 78%−81%of the original CMST to 81%−89%.The total coverage after 1955 reached about 93%,including more than 98%in the Northern Hemisphere and 81%−89%in the Southern Hemisphere.Through the reconstruction ensemble experiments with different parameters,a good basis is provided for more systematic uncertainty assessment of C-LSAT2.0 and CMSTInterim.In comparison with the original CMST,the global mean surface temperatures are estimated to be cooler in the second half of 19th century and warmer during the 21st century,which shows that the global warming trend is further amplified.The global warming trends are updated from 0.085±0.004℃(10 yr)^(–1)and 0.128±0.006℃(10 yr)^(–1)to 0.089±0.004℃(10 yr)^(–1)and 0.137±0.007℃(10 yr)^(–1),respectively,since the start and the second half of 20th century. | Wenbin SUN Qingxiang LI Boyin HUANG Jiayi CHENG Zhaoyang SONG Haiyan LI Wenjie DONG Panmao ZHAI Phil JONES | 2021 | Advances in Atmospheric Sciences2021，38，5： | 8 |
| 12 | Effect of Rare Earth Elements on Austenite Growth Dynamics of Steel 9Cr2Mo显示文摘The growth dynamics of austenite grain was investigated in steel 9Cr2 Mo with different rare earth(RE)element addition.The results show that austenite grains of steel 9Cr2 Mo can be refined and their growth can be restrained by adding a certain amount of RE.According to the results,the n and Q were calculated and the mechanism of the refinement of austenite grains was discussed. | Yang Qingxiang Wang Airong Gao Ming Wu Haoquan Guo Tiebo | 1996 | Journal of Iron and Steel Research(International)1996，3，1： | 8 |
| 13 | Reconstituted high-density lipoproteins: novel biomimetic nanocarriers for drug delivery显示文摘High-density lipoproteins(HDL) are naturally-occurring nanoparticles that are biocompatible,non-immunogenic and completely biodegradable. These endogenous particles can circulate for an extended period of time and transport lipids, proteins and micro RNA from donor cells to recipient cells.Based on their intrinsic targeting properties, HDL are regarded as promising drug delivery systems. In order to produce on a large scale and to avoid blood borne pollution, reconstituted high-density lipoproteins(rHDL) possessing the biological properties of HDL have been developed. This review summarizes the biological properties and biomedical applications of rHDL as drug delivery platforms. It focuses on the emerging approaches that have been developed for the generation of biomimetic nanoparticles rHDL to overcome the biological barriers to drug delivery, aiming to provide an alternative,promising avenue for efficient targeting transport of nanomedicine. | Xinyi Ma Qingxiang Song Xiaoling Gao | 2018 | Acta Pharmaceutica Sinica B2018，8，1： | 7 |
| 14 | Molecule modification and mass deposition induced by the implantation of low energy Fe^+ ion beams into amino acids显示文摘Fe+ ion beams with the energy of 110 keV were implanted into films of L(+)-cysteine (HSCH2CH(NH2)COOH). One of the single crystals grown in hydrochloric acid solution with the implanted samples through slow evaporation was structurally characterized by the X-ray crystallography. The crystal is monoclinic, space group C2, with a = 1.8534(4) nm, b=0.5234(1) nm, c = 0.7212(1) nm, β=103.722°, V = 0.67965(3) nm3, Z = 4, F(000) = 144.0, Dclac = 1.763 g·cm-3, μ (MoKa) = 1.06 mm-1, T = 293(2) K.R = 0.0379, wR = 0.0835 for 660 observed reflections (I>2σ(I)). The structural formula of the crystal compound is (CH2CH(NH2)NO2)ClFe (Mr = 180.38u). Products of heavy ion beam irradiation were purified and it was directly confirmed that the implanted Fe+ ions had been deposited in the novel molecules. The same doses of Fe+ ion beams of the same energy were implanted into films of L(+)-cysteine hydrochloride monohydrate. FTIR spectroscopy of the implanted samples proved that some of the original molecules were | YUAN Shibin WEI Zengquan GAO Qingxiang | 2002 | Chinese Science Bulletin2002，47，8： | 6 |
| 15 | 3D stability analysis method of concave slope based on the Bishop method显示文摘In order to study the stability control mechanism of a concave slope with circular landslide, and remove the influence of differences in shape on slope stability, the limit analysis method of a simplified Bishop method was employed. The sliding body was divided into strips in a three-dimensional model, and the lateral earth pressure was put into mechanical analysis and the three-dimensional stability analysis methods applicable for circular sliding in concave slope were deduced. Based on geometric structure and the geological parameters of a concave slope, the influence rule of curvature radius and the top and bottom arch height on the concave slope stability were analyzed. The results show that the stability coefficient decreases after growth, first in the transition stage of slope shape from flat to concave, and it has been confirmed that there is a best size to make the slope stability factor reach a maximum. By contrast with average slope, the stability of a concave slope features a smaller range of ascension with slope height increase, which indicates that the enhancing effect of a concave slope is apparent only with lower slope heights. | Zhang Tianwen Cai Qingxiang Han Liu Shu Jisen Zhou Wei | 2017 | International Journal of Mining Science and Technology2017，27，2： | 6 |
| 16 | Effect of preparation methods on the structure and catalytic performance of Fe–Zn/K catalysts for CO2 hydrogenation to light olefins显示文摘Potassium promoted iron–zinc catalysts prepared by co-precipitation method(C–Fe–Zn/K),solvothermal method(S–Fe–Zn/K)and hydrothermal method(H–Fe–Zn/K)could selectively convert CO_2to light olefins,respectively.The physicochemical properties of the obtained catalysts were determined by SEM,N_2physisorption,XRD,H_2-TPR,CO_2-TPD and XPS measurements.The results demonstrated that preparation methods had great influences on the morphology,phase structures,reduction and adsorption behavior,and hence the catalytic performance of the catalysts.The samples prepared by hydrothermal and co-precipitation method generated small uniform particles and led to lower specific surface area.In contrast,microspheres with larger specific surface area were formed by self-assembly of nanosheets using solvothermal method.ZnFe_2O_4was the only detectable phase in the fresh C–2Fe–1Zn/K,S–3Fe–1Zn/K and S–2Fe–1Zn/K samples.ZnFe_2O_4and ZnO co-existed with increasing Zncontent in S–1Fe–1Zn/K sample,while ZnO and Fe_2O_3could be observed over H–2Fe–1Zn/K sample.All the used samples contained Fe_3O_4,ZnO and Fe_5C_2.The peak intensity of ZnO was strong in the AR-H–2Fe–1Zn/K sample while it was the lowest in the AR-C–2Fe–1Zn/K sample after reaction.The formation of ZnFe_2O_4increased the interaction between iron and zinc for C–2Fe–1Zn/K and S–Fe–Zn/K samples,causing easier reduction of Fe_2O_3to Fe_3O_4.The surface basicity of the sample prepared by co-precipitation method was much more than that of the other two methods.During CO_2hydrogenation,all the catalysts showed good activity and olefin selectivity.The CO selectivity was increased with increasing Zncontent over S–Fe–Zn/K samples.H–2Fe–1Zn/K catalyst preferred to the production of C_5^+hydrocarbons.CO_2conversion of 54.76%and C_2~=–C_4~=contents of 57.38%were obtained on C–2Fe–1Zn/K sample,respectively. | Xu Wang Jianli Zhang Jingyu Chen Qingxiang Ma Subing Fan Tiansheng Zhao | 2018 | Chinese Journal of Chemical Engineering2018，26，4： | 6 |
| 17 | Geochronology and geochemistry of Permo-Triassic sandstones in eastern Jilin Province(NE China): Implications for final closure of the Paleo-Asian Ocean显示文摘In the eastern part of the Central Asian Orogenic Belt(CAOB) in northeastern(NE) China, scattered outcrops of molasse deposits mark the ending of an orogeny and are crucial for understanding the evolution of the Paleo-Asian Ocean(PAO). However, the timing of tectonic events and the relationships among these strata remain controversial. To better constrain these geologic events, a comprehensive study of the detrital zircon U-Pb geochronology and geochemistry of the sandstones of the Kaishantun(KST) Formation and Kedao(KD) Group in eastern Jilin Province, NE China, was conducted. The KST Formation is traditionally considered a molasse deposit. The sandstones display low CIA, PIA and high ICV values and low Th/U and Rb/Sr ratios, which suggest that the rocks were derived from an immature intermediate-felsic igneous source and experienced a simple sedimentary recycling history with relatively weak chemical weathering. LA-ICP-MS U-Pb dating of detrital zircons from two samples of the KST Formation yields ages of 748-252 Ma, suggesting that the KST Formation was deposited between 254.5 Ma and 252 Ma in Late Permian. The zircons were mainly derived from the continental northern part of the North China Craton(NCC). In contrast, the U-Pb dating of detrital zircons from five samples of the KD Group yields ages of 2611-230 Ma, suggesting that the KD samples were deposited in the Early to Middle Triassic(ca. 248-233 Ma). The detrital zircon ages for the KD samples can be divided into groups with peaks at 2.5 Ga, 1.8 Ga, 800-1000 Ma, 500 Ma and 440-360 Ma, which suggest that the samples were derived from bidirectional provenances in the Jiamusi-Khanka Block and the NCC. These new data,combined with previously published results, suggest that at least three orogenic events occurred in central-eastern Jilin Province during the Early Permian(270-262 Ma), Early Triassic(254-248 Ma) and Middle-Late Triassic(242-227 Ma). The final closure of the PAO occurred during 242-227 Ma in the Middle-Late Triassic along the Changchun-Yanji suture zone. The detrital zircon geochronological data clearly record plate convergence and the scissor-like closure of the PAO in the eastern CAOB. | Qingxiang Du Zuozhen Han Xiaoli Shen Chao Han Zhigang Song Lihua Gao Mei Han Wenjian Zhong | 2019 | Geoscience Frontiers2019，10，2： | 6 |
| 18 | Modified Blumgart anastomosis without pancreatic duct-to-jejunum mucosa anastomosis for pancreatoduodenectomy:a feasible and safe novel technique显示文摘Objective:This study proposed a modified Blumgart anastomosis(m-BA)that uses a firm ligation of the main pancreatic duct with a supporting tube to replace the pancreatic duct-to-jejunum mucosa anastomosis,with the aim of simplifying the complicated steps of the conventional BA(c-BA).Thus,we observe if a difference in the risk of postoperative pancreatic fistula(POPF)exists between the two methods.Methods:The m-BA anastomosis method has been used since 2010.From October 2011 to October 2015,147 patients who underwent pancreatoduodenectomy(PD)using BA in Tianjin Medical University Cancer Institute and Hospital were enrolled in this study.According to the type of pancreatojejunostomy(PJ),50 patients underwent m-BA and 97 received c-BA.The two patient cohorts were compared prospectively to some extent but not randomized,and the evaluated variables were operation time,the incidence rate of POPF,and other perioperative complications.Results:The operation time showed no significant difference(P>0.05)between the two groups,but the time of duct-to-mucosa anastomosis in the m-BA group was much shorter than that in the c-BA group(P<0.001).The incidence rate of clinically relevant POPF was 12.0%(6/50)in the modified group and 10.3%(10/97)in the conventional group(P>0.05),which means that the modified anastomosis method did not cause additional pancreatic leakage.The mean length of postoperative hospital stay of the m-BA group was 23 days,and that of the c-BA group was 22 days(P>0.05).Conclusions:Compared with the conventional BA,we suggest that the modified BA is a feasible,safe,and effective operation method for P J of PD with no sacrifice of surgical quality.In the multivariate analysis,we also found that body mass | Xiaoqing Wang Yang Bai Mangmang Cui Qingxiang Zhang Wei Zhang Feng Fang Tianqiang Song | 2018 | Cancer Biology & Medicine2018，15，1： | 6 |
| 19 | Effects of glucose on the decolorization of Reactive Black 5 by yeast isolates显示文摘葡萄糖的 cometabolic 角色在偶氮的染料的 decolorization 被调查,反应黑色 5,由酵母孤立, Debaryomyces 多形体我们和 Candida 热带。结果显示由二酵母的染料降级高度在媒介与酵母生长过程和葡萄糖存在被联系。200 mg dye/L 的颜色移动从 5 ~ 10 g/L 随葡萄糖的增加在 18 24 h 以内在 60 h 以内从 76.4% ~ 92.7% 被增加到 100% ,尽管锰依赖者过氧化物酶(MnP ) 的活动在这种情况中到 2 8 次减少了。233.3 μ g /L 的过氧化氢在 6 hin D 被检测。多形体我们文化。葡萄糖和过氧化氢的 cometabolic 功能能被 95.8% 或 78.9% 的进一步的颜色移动也在 7 g glucose/L 或 250 μ g H2O2/L 和 200 mg dye/L 分别地被外加的 decolorization 测试的第二个周期证实。 | YANG Qingxiang TAO Lingxia YANG Min ZHANG Hao | 2008 | Journal of Environmental Sciences2008，20，1： | 6 |
| 20 | Synthesis of a reduction-sensitive Bletilla striata polysaccharide amphiphilic copolymer显示文摘Recently, much special attention has been focused on the development of amphiphilic copolymers.Herein, a reduction-sensitive stearic acid grafted-Bletilla striata polysaccharide copolymer(BSP-ss-SA)was synthesized and characterized. BSP-ss-SA copolymer could spontaneously form micelles with an average particle size of(106 ? 4.36) nm. Particle sizes were dramatically larger under 10 mmol/L dithiothreitol(DTT) than that in absence of 10 mmol/L DTT. Docetaxel loading content and encapsulation efficiency of micelles were 5.94 wt% and 72.75 wt%, respectively. The docetaxel release rate in vitro in micelles could be remarkably accelerated in pH 7.4 phosphate buffer solution(PBS) containing 10 mmol/L DTT compared with that of micelles(0 mmol/L DTT). Furthermore, MTT results demonstrated the anticancer activities in vitro of docetaxel-loaded BSP-ss-SA micelles on HepG2 were superior to that of docetaxel injection. BSP-ss-SA copolymer might be a promising nanocarrier for cancer chemotherapy drugs. | Dandan Sun Miao Wang Danyang Ji Jin Qiao Tong He Xin Liu Qingxiang Guan | 2018 | Chinese Chemical Letters2018，29，6： | 5 |
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