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| 1 | Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders显示文摘Deep brain stimulation(DBS) is emerging as a pow-erful tool for the alleviation of targeted symptoms in treatment-resistant neuropsychiatric disorders. Despite the expanding use of neuropsychiatric DBS, the mecha-nisms responsible for its effects are only starting to be elucidated. Several modalities such as quantitative elec-troencephalography as well a intraoperative recordings have been utilized to attempt to understand the under-pinnings of this new treatment modality, but functional imaging appears to offer several unique advantages. Functional imaging techniques like positron emission tomography, single photon emission computed tomog-raphy and functional magnetic resonance imaging have been used to examine the effects of focal DBS on activ-ity in a distributed neural network. These investigations are critical for advancing the field of invasive neuro-modulation in a safe and effective manner, particularly in terms of defining the neuroanatomical targets and refining the stimulation protocols. The purpose of this review is to summarize the current functional neuroim-aging findings from neuropsychiatric DBS implantation for three disorders: treatment-resistant depression, obsessive-compulsive disorder, and Tourette syndrome. All of the major targets will be discussed(Nucleus ac-cumbens, anterior limb of internal capsule, subcallosal cingulate, Subthalamic nucleus, Centromedial nucleus of the thalamus-Parafasicular complex, frontal pole, and dorsolateral prefrontal cortex). We will also address some apparent inconsistencies within this literature, and suggest potential future directions for this promis-ing area. | Nolan R Williams Joseph J Taylor Kayla Lamb Colleen A Hanlon E Baron Short Mark S George | 2014 | World Journal of Radiology2014，6，10： | 6 |
| 2 | NGF, DCX, and NSE upregulation correlates with severity and outcome of head trauma in children显示文摘 | A Chiaretti G Barone R Riccardi A Antonelli P Pezzotti O Genovese L Tortorolo G Conti | 2009 | Neurology2009，，7： | 3 |
| 3 | The moderator-mediator vairable distinction in social psychological research:conceptual,strategic,and statistical considerations显示文摘 | BARON R M KENNY D A | 1986 | J Pers Soc Psychol1986，51，6： | 1 |
| 4 | The moderator - mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations 显示文摘 | Baron R M Kenny D A | 1986 | Journal of Personality and Social Psychology1986，51，： | 1 |
| 5 | The moderator-mediator variable distinction in social psychological research: Concep- tual, strategic, and statistical considerations 显示文摘 | Baron R M Kenny D A | 1986 | Journal of Personality and Social Psychology1986，51，6： | 1 |
| 6 | The moderator-mediator varia- ble distinction in social psychological research: Con- ceptual, strategic, and statistical considerations显示文摘 | Baron R M Kenny D A | 1986 | Journal of Personality and Social Psychology1986，51，6： | 1 |
| 7 | The Moderator-Mediator Variable Distinction in Social Psychological Research:Conceptual, Strategic ,and Statistical Considerations显示文摘 | Baron R M kenny D A | 1986 | Journal of Per- sonality and Social Psychology1986，51，6： | 1 |
| 8 | Medical tourism and health care outsourcing in a global world显示文摘 | Viladrich A Baron F R | 2012 | Advances in Medicine and Biology2012，61，1： | 1 |
| 9 | Opportunity recognition as the detection of meaningful patterns: Evidence from comparisons of novice and experienced entrepre- neurs显示文摘 | Baron R A Ensley M D | 2006 | Management Science2006，52，9： | 1 |
| 10 | The Moderator-mediator Variable Distinction in Social Psychological Research:Conceptual,Strategic,and Statistical Considerations显示文摘 | Baron R M David D A | 1986 | Journal of Personality and Social Psychology1986，51，6： | 1 |
| 11 | The moderator-mediator variable distinction in social psychological research: conceptual stragetic, and statistical considerations显示文摘 | BARON R M KENNY D A | 1986 | Journal of Personality and Social Psychology1986，51，6： | 1 |
| 12 | Person-entrepreneurship fit: Why some people are more successful as entrepreneurs thanothers显示文摘 | Markman D G and Baron A R | 2003 | Human Resource Management Review2003，13，2： | 1 |
| 13 | The Moderator Variable Distinction inSocial Psychological Research: Conceptual, Strategic, and StatisticalConsiderations 显示文摘 | BARON R M DAVID A K | 1999 | J Clin Psychy1999，60，9： | 1 |
| 14 | The Moderator - mediator Variable Distinction in Social Psychological Research:Conceptu- al, Strategic and Statistical Considerations显示文摘 | Baron R M Kenny D A | 1986 | Journal of Person- ality and Social Psychology1986，51，06： | 1 |
| 15 | A clinical study of the out- tomes and complications associated with maxillary sinus augmentation 显示文摘 | Barone A SS Sbordone L Crespi R | 2006 | fnt J Oral MaxiIlofac Implants2006，21，1： | 1 |
| 16 | Neuropathic pain:diagnosis,pathophysiological mechanisms,and treatment显示文摘 | Baron R Binder A Wasner G | | 0，，08： | 1 |
| 17 | The moderator-mediator variable distinc- tion in social psychological research: Conceptual, strategic, and sta- tistical considerations显示文摘 | Baron R M Kermy D A | 1986 | Journal of Personality and Social Psychol- ogy1986，51，6： | 1 |
| 18 | The moderator-mediator variable distinction in social psychological research Conceptual, strategic, and statistical considerations 显示文摘 | Baron R M Kenny D A | 1986 | Journal of Personality and Social Psychology1986，51，6： | 1 |
| 19 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations 显示文摘 | Baron R M Kenny D A | 1986 | Journal of Personality and Social Psychology1986，51，6： | 1 |
| 20 | The moderator-mediator variable distinction in social psychological research:conceptual,strategic,and statistical considerations显示文摘 | BARON R M KENNY D A | 1986 | Journal of Personality and Social Psychology1986，21，2： | 1 |
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