维普期刊资源整合服务平台（V6.5）

209篇 您的检索式：作者名="R Gent"

选中清除导出查看参考文献查看引证文献引用追踪共11页首页上一页第1页下一页末页 /11 跳转

	题名	作者	年代	出处	被引量
1	Why interleukin-10 supplementation does not work in Crohn's disease patients显示文摘Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) or ulcerative colitis are chronic intestina disorders, which are on the increase in 'Westernised' countries. IBD can be caused by both genetic and environmental factors. Interleukin-10 (IL-10) is an immunoregulatory cytokine that has been identified as being involved in several diseases including IBD. Studies have shown that polymorphisms in the promoter region reduce serum levels of IL-10 and this reduction has been associated with some forms of IBD. Mouse models have shown promising results with IL-10 supplementation, as such IL-10 supplementation has been touted as being a possible alternative treatment for CD in humans. Clinical trials have shown that recombinant human IL-10 is safe and well tolerated up to a dose o 8 μg/kg. However, to date, the results of the clinica trials have been disappointing. Although CD activity was reduced as measured by the CD activity index IL-10 supplementation did not result in significantly reduced remission rates or clinical improvements when compared to placebo. This review discusses why IL-10supplementation is not effective in CD patients currently and what can be addressed to potentially make IL-10 supplementation a more viable treatment option in the future. Based on the current research we conclude that IL-10 supplementation is not a one size fits all treatment and if the correct population of patients is chosen then IL-10 supplementation could be of benefit.	Gareth J Marlow Dominique van Gent Lynnette R Ferguson	2013	World Journal of Gastroenterology2013，19，25：	9
2	Comparative study of two whole-body imaging techniques in the case of melanoma metastases: Advantages of multi-contrast MRI examination including a diffusion-weighted sequence in comparison with PET-CT显示文摘	Valérie Laurent Grégory Trausch Olivier Bruot Pierre Olivier Jacques Felblinger Denis Régent	2009	European Journal of Radiology2009，，3：	2
3	In- cidence and determinants of lower extremity running injuries in long distance runners: a systematic submitted for publication 显示文摘	VAN GENT R N SIEM D VAN MIDDELKOOP M	2007	Brit J Sports Med2007，41，8：	1
4	Viral-bacterial interactions and risk of acute otitis media complicating upper respiratory tract infection 显示文摘	PETTIGREW M M GENT J F PYLES R B	2011	J ClinMicrobiol2011，49，：	1
5	The community climatesystem model version 4 显示文摘	Gent P R Danabasoglu G Donner L J	2011	J Climate2011，24，：	1
6	Long-term restoration of the human T-cell compartment after thymectomy during infancy: a role for thymic regeneration?显示文摘	van Gent R Schadenberg AW Otto SA	2011	Blood2011，118，3：	1
7	Half-wavelength power transmis- sion lines显示文摘	Hubert G J Gent M R	1965	IEEE Trans on Power Apparatus and Sys- tems1965，84，10：	1
8	Increased risk of atherosclerosis by elevated plasma levels of phospholipid transfer protein显示文摘	VAN HAPEREN R VAN TOL A VAN GENT T	2002	J Biol Chem2002，277，48：	1
9	Predicting Time Series by a Fully Corrected Neural Network Trained by Back Propagation显示文摘	Sheppard C P	1992	Computing and Control Engineering Journal1992，12，5：	1
10	The community climate system model version 4显示文摘	Gent P R Danabasoglu G Donner L J	2011	Journal of Climate2011，24，19：	1
11	Peel mechanics for an elastic-plastic adherend 显示文摘	Gent A N Hamed G R	1977	J Appl Polymer Sci1977，21，：	1
12	Canadian implantable defibrillator study(CIDS):a random ized trial of implantable cardioverter defibrillator against am iodarone显示文摘	CCONNOLLY S I GENT M ROBERTS R S	2000	Circulation2000，101，：	1
13	Elevation of plasma phospholipid transfer protein in transgenic mice increases VLDL secretion显示文摘	LIE J DE CROM R VAN GENT T	2002	J Lipid Res2002，43，11：	1
14	Half-wavelength power transmission lines显示文摘	Hubert F J Gent M R	1965	IEEE Trans on Power Apparatus and Systems1965，84，10：	1
15	Predicting time series by a fully cor- rected neural network trained by back propagation 显示文摘	GENT C R SHEPPARD C P	1992	Computing and Control Engineering Journal1992，12，5：	1
16	Elevation of plasma phospholipid transfer protein increases the risk of atherosclerosis despite lower apolipoprotein B-containing lipoproteins显示文摘	LIE J DE CROM R VAN GENT T	2004	J Lipid Res2004，45，5：	1
17	Half-wavelength power transmission lines显示文摘	Hubert F J Gent M R	1965	IEEE Trans on Power Apparatus and Systems1965，84，10：	1
18	Peel mechanics for an elastic-plastic adherend显示文摘	Gent A N Hamed G R	1977	J Appl Polymer Sci1977，21，：	1
19	The Community Climate System Model Version 4显示文摘	Gent P R Danabasoglu G	2011	Journal of Climate2011，19，24：	1
20	Half-wavelength power transmission lines显示文摘	Hubert F J Gent M R	1965	IEEE Trans on Power Apparatus and Systems1965，84，10：	1

返回顶部每页显示：

共11页首页上一页第1页下一页末页 /11 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示