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| 1 | Diabetic neuropathic pain:Physiopathology and treatment显示文摘Diabetic neuropathy is a common complication of both type 1 and type 2 diabetes,which affects over 90% of the diabetic patients.Although pain is one of the main symptoms of diabetic neuropathy,its pathophysiological mechanisms are not yet fully known.It is widely accepted that the toxic effects of hyperglycemia play an important role in the development of this complication,but several other hypotheses have been postulated.The management of diabetic neuropathic pain consists basically in excluding other causes of painful peripheral neuropathy,improving glycemic control as a prophylactic therapy and using medications to alleviate pain.First line drugs for pain relief include anticonvulsants,such as pregabalin and gabapentin and antidepressants,especial y those that act to inhibit the reuptake of serotonin and noradrenaline.In addition,there is experimental and clinical evidence that opioids can be helpful in pain control,mainly if associated with first line drugs.Other agents,including for topical application,such as capsaicin cream and lidocaine patches,have also been proposed to be useful as adjuvants in the control of diabetic neuropathic pain,but the clinical evidence is insufficient to support their use.In conclusion,a better understanding of the mechanisms underlying diabetic neuropathic pain will contribute to the search of new therapies,but also to the improvement of the guidelines to optimize pain control with the drugs currently available. | Anne K Schreiber Carina FM Nones Renata C Reis Juliana G Chichorro Joice M Cunha | 2015 | World Journal of Diabetes2015，6，3： | 34 |
| 2 | Acute gouty synovitis associated with 'urate milk' 显示文摘 | FAM A G REIS M D SZALAI J P | 1997 | J Rheumatol1997，24，12： | 1 |
| 3 | Vanadium oxide nanostructures derived from a novel vanadium(Ⅳ) alkoxide precursor显示文摘 | Willian G Menezes Dayane M Reis | 2007 | Chem Phys Lett2007，445，46： | 1 |
| 4 | Integrated transport and reaction in an ion exchange membrane bioreactor 显示文摘 | Velizarov S Reis M A M Crespo J G | 2002 | Desali- nation2002，149，13： | 1 |
| 5 | Experimental analy- sis of an all-optical packet router显示文摘 | Reis C Parca G Bougioukos M | 2014 | Journal of Optical Communications and Networking2014，6，7： | 1 |
| 6 | Effect of spacing and age on nitrogen and phosphorus distribution in biomass of Eucalyptus camaldulensis,Eucalyptus pellita and Eucalyptus urophylla plantations in southeastern Brazil显示文摘 | Harrison R B Reis G G Reis M D G F | 2000 | Forest Ecology and Management2000，133，3： | 1 |
| 7 | Removal of trace mono-valent inorganic pollutants in an ion exchange membrane bioreactor: analysis of transport rate in a denitrification process 显示文摘 | VELIZAROV S REIS M A CRESPO J G | 2003 | Journal of Membrane Science2003，217，12： | 1 |
| 8 | Localization and pattern of expression of a female specific mRNA in Schistosoma mansoni显示文摘 | Reis M G Kuhns J Blanton R | 1989 | Mol Biochem Parasitol1989，32，： | 1 |
| 9 | Removal of tracemono-valent inorganic pollutants in an ion exchange membrane bio- reactor: Analysis of transport rate in a denitrification process 显示文摘 | Velizarov S Reis M A M Crespo J G | 2003 | Journal of Membrane Science2003，217，12： | 1 |
| 10 | Validation of a matrix solid phase dispersion (MSPD) technique for determination of pesticides in lyophilized eggs of the chicken Gallus gallus domesticus显示文摘 | dos Reis Souza M K Moreira C O de Lima T G | 2013 | Microchem J2013，110，： | 1 |
| 11 | Integrated transport and reaction in an ion exchange membrane bioreactor显示文摘 | Velizarov S Reis M A Crespo J G | 2002 | Desalination2002，149，： | 1 |
| 12 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G Yuan Z Kelley J Blackall L L Reis M A M | 2007 | Water Research2007，41，11： | 1 |
| 13 | Clarification and purification of aqueous Stevia extract using membrane separation process 显示文摘 | REIS M H M SILVA F V ANDRADE C M G | 2009 | Journal of Food Process Engineering2009，32，3： | 1 |
| 14 | Growth of pruned eucalypt clone in an agroforestry system in southeastern Brazil显示文摘 | FONTAN I REIS G REIS F M | 2011 | Agroforestry Systems2011，83，2： | 1 |
| 15 | EIS investigation on A1 5052 alloy surface preparation for self-assembling monolayer显示文摘 | Reis F M DeMelo H G Costa I | 2006 | Electrochimica Acta2006，51，： | 1 |
| 16 | Removal of trace mono-valent inorganic pollutants in an ion exchange membrane bioreactor:analysis of transport rate in a denitrification process显示文摘 | Velizarov S Reis M A Crespo J G | 2003 | Journal of Membrane Science2003，217，： | 1 |
| 17 | Bone plasticity in response to exercise is sex-dependent in rats显示文摘 | VICENTE W S DOS REIS L M GRACIOLLI R G | 2013 | PLoS One2013，8，64： | 1 |
| 18 | Purification and characterization of Aspergillus terreus a-galactosidases and their use for hydrolysis of soymilk oligosaccharides显示文摘 | FERREIRA J G REIS A P GUIMARAES V M | 2011 | Applied Biochemistry and Biotechnology2011，164，7： | 1 |
| 19 | Towards design principles for optimal transport networks显示文摘 | Li G Reis S D S M oreira A A | 2010 | PRL2010，104，01： | 1 |
| 20 | Ion exchange membrane bioreactor for selective removal of nitrate from drinking water:Control of ion fluxes and process performance显示文摘 | Velizarov S Crespo J G Reis M A | 2002 | Biotechnol Progress2002，18，： | 1 |
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