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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Effect of the preparation method on the catalytic activity of La1_xCaxFeO3 perovskite-type oxides显示文摘 | Pecchi G Reyes P Zamora R Campos C | 2008 | Catalysis Today2008，，： | 1 |
| 3 | Speech/music classification based on distributed evolutionary fuzzy logic for intelligent audio coding显示文摘 | Munoz J E Reyes N R Galan S G | 2007 | Pattern Recognition and Image2007，4478，： | 1 |
| 4 | Efficient multi-camera vehicle detection, tracking, and identification in a tunnel surveil- lance application 显示文摘 | Reyes R C Tinne T Lue V G | 2012 | Computer Vision and Image Understanding2012，116，： | 1 |
| 5 | Properly assess maldistribution in packed towers 显示文摘 | KILLAT G R REY T D | 1996 | Chemical Engineering and Processing1996，92，3： | 1 |
| 6 | Ozonolysis of cinnamic acid in water medium显示文摘 | Aguilar G Perez Rey R Baluja C | 2001 | Ozone: Science & Engineering2001，23，2： | 1 |
| 7 | Characterization by computed X-Ray tomography of the evolution of the pore structure of a dolomite rock during freeze-thaw cyclic tests显示文摘 | DE ARGANDONA R V G REY A R CELORIO C | | 0，，： | 1 |
| 8 | Sequence-independent, single-primer amplification(SISPA) of complex DNA populations显示文摘 | Reyes G R Kim J P | 1991 | Mol Cell Probes1991，5，： | 1 |
| 9 | Isolation ora cDNA fiom the virus responsible for enterically transmitted non-A,non-B hepatitis显示文摘 | Reyes G R Purdy M A KimJ p | 1990 | Science1990，，247： | 1 |
| 10 | Surface properties and performance for VOCs combustion of LaFel yNiyO3 perovskite oxides显示文摘 | Pecchi G Reyes P Zamora R | 2008 | Journal of Solid State Chemistry2008，181，4： | 1 |
| 11 | Ameloblasticcarcinoma: report of an aggressive case with multiple bonymetastases 显示文摘 | Datta R Winston JS Diaz -Reyes G | 2003 | Am J Otolaryngol2003，24，1： | 1 |
| 12 | Composition controlled spin polarization in Co1-x FexS2 alloys 显示文摘 | C Leighton M Manno A Cady J W Freeland L Wang K Umenoto R M Wentzcovitch T Y Chen C L Chien P L Kuhns M J R Hoch A P Reyes W G Moulton E D Dahlberg J Checkelsky J Eckert | 2007 | Journal of Physics : Condensed Matter2007，19，31： | 1 |
| 13 | Polarographic determination of nitrate in vegetables显示文摘 | Ximenes M I N Rath S Reyes F G R | 2000 | Talanta2000，51，1： | 1 |
| 14 | Characterization by computed X-ray tomography of the evolution of the pore structure of a dolomite rock during freeze-thaw cyclic tests 显示文摘 | Ruiz de Argandona V G Rey A R Celorio C | 1999 | Physics and Chemistry of the Earth Part A: Solid Earth and Geodesy1999，24，7： | 1 |
| 15 | NT-proBNP in cardiac surgery:a new tool for the management of our patients 显示文摘 | Reyes G Fores G Rodriguez-Abella R H | 2005 | Interactive Cardiovas Thorac Surg2005，4，3： | 1 |
| 16 | Characterization by computed X-ray tomography of the evolution of the pore structure of a dolomite rock during freeze-thaw cyclic tests 显示文摘 | RUIZDE ARGANDONA V G REY A R CELORIO C | 1999 | Physical Chemical and Earth Sciences (A)1999，24，7： | 1 |
| 17 | Numerical and experimental investigations of the cavitating behavior of an inducer显示文摘 | Bakir F Rey R Gerber A G | 2004 | International Journal of Rotating Machinery2004，10，1： | 1 |
| 18 | Use of quantitative methods to determine leaf biomass on 15 woody shrub species in northeastern Mexico显示文摘 | FOROUGHBAKHCH R REYES G ALVARADO-VAZQUEZ M A | 2005 | Forest Ecology and Management2005，216，： | 1 |
| 19 | Harmonic balance methods for nonlinear feedback identification 显示文摘 | Casas R A Jacobson C A Rey G J | 1997 | Allerton1997，2，： | 1 |
| 20 | Evaluation of seven procedures for detection of abnormal milk due to mastitis显示文摘 | Read R B Reyes A L Bradshaw J G | 1969 | Journal of Dairy Science1969，52，13： | 1 |
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