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| 1 | Gastric cancer in a Caucasian population: Role of pepsinogen C genetic variants显示文摘瞄准:在胃蛋白酶原 C (PGC ) 基因学习插入 / 删除多型性的角色,为胃粘膜的终端区别的一个有效标记,在到胃的损害的开发的危险性。方法:没有肿瘤的疾病的证据,学习与已知的胃的损害的 99 件样品和 127 件样品被执行。PCR 被采用, 6 多态的等位基因被放大:等位基因 1 (510 bp ) ,等位基因 2 (480 bp ) ,等位基因 3/4 (450/460 bp ) ,等位基因 5 (400 bp ) 并且等位基因 6 (310 bp ) 。结果:我们的结果表明等位基因 6 搬运人似乎对任何胃的损害的发展有保护(或 = 0.34;P<0.001 ) ,与象萎缩或肠的组织变形那样的胃的腺癌联系的 non-dysplastic 损害(或 = 0.28;P<0.001 ) 或侵略 GC (或 = 0.39;P = 0.004 ) 。结论:我们的学习表明等位基因 6 搬运人地位在胃的损害的发展有一个保护的角色,可能由于它有 PGC 的更高的表示的协会。而且,在控制组的等位基因 6 搬运人的频率比在亚洲人口获得了高是远的,它可能代表在白种人和亚洲人口之间的基因差距。 | Ana L Pinto-Correia Hugo Sousa Maria Fragoso Luís Moreira-Dias Carlos Lopes Rui Medeiros Mário Dinis-Ribeiro | 2006 | World Journal of Gastroenterology2006，12，31： | 6 |
| 2 | Association between EGF +61A/G polymorphism and gastric cancer in Caucasians显示文摘AIM: To investigate the association between epidermal growth factor (EGF) +61A/G polymorphism and susceptibility to gastric cancer, through a cross-sectional study. METHODS: Polymerase chain reaction resctriction fragment lenght polymorphism analyses were used to genotype EGF +61 in 207 patients with gastric lesions (162 patients with gastric adenocarcinomas, 45 with atrophy or intestinal metaplasia) and 984 controls. All subjects were Caucasian. RESULTS: Genotype distribution was 23.5% for GG and 76.5% for GA/AA in the control group, 18.4% for GG and 68.6% for GA/AA in the entire group with gastric lesions and 17.9% for GG and 82.1% for GA/AA in the group with gastric adenocarcinoma. No statistically significant associations were found between EGF +61 variants and risk for developing gastric cancer [odds ratios (OR) = 1.41, 95% confidence intervals (CI): 0.90-2.21, P = 0.116]. However, the stratification of individuals by gender revealed that males carrying A alleles (EGF +61A/G or AA) had an increased risk for developing gastric cancer as compared to GG homozygous males (OR = 1.55, 95% CI: 1.05-2.28, P = 0.021). CONCLUSION: In summary, we found that males who were A carriers for EGF +61 had an increased risk for developing gastric cancer. This result may be explained by the suggestion that women secrete less gastric acid than men. | Ana Paula Araújo Bruno M Costa Ana L Pinto-Correia Maria Fragoso Paula Ferreira Mário Dinis-Ribeiro Sandra Costa Rui M Reis Rui Medeiros | 2011 | World Journal of Gastroenterology2011，17，4： | 3 |
| 3 | GM1 ganglioside treatment protects against long-term neu- rotoxic effects of neonatal X-irradiation on cerebellar cor- tex cytoarchitecture and motor function 显示文摘 | Guelman L R Zorrilla Zubilete M A Rios H | 2008 | Brain Res2008，858，2： | 1 |
| 4 | The empty sella turcica syndnmle associated wit 11 hypopituitarisnl显示文摘 | BARRIOS F J L RIOS V M J GARRID R H et td | 1999 | An Medlnter- ha1999，16，： | 1 |
| 5 | Natural senescence of pea leaves(an activated-oxygen-mediated function for peroxisomes) 显示文摘 | Pastori G M Del Rio L A | 1997 | Plant Physiology1997，113，2： | 1 |
| 6 | Value of indirect hem agglutination and coagglutiation test for serotyping Haemophilus parasuis显示文摘 | Del Rio M L Gut ierrez B C Rodriguez Ferri E F | 2003 | Clin Microbio 12003，41，2： | 1 |
| 7 | Cytotoxic activity of moronic acid and identification of the new triterpene 3,4-seco-olean-18-ene-3,28-dioic acid from Phoradendron reichenbachianum显示文摘 | RIOS M Y SALINA D VILLARREAL M L | 2001 | Planta Med2001，67，5： | 1 |
| 8 | Defective human T - cell lympho- tropic virus type I (HTLV -I) provirus in 10 Chilean seronegative pa- tients with tropical spastic paraphrases or HTLV - I - associated myelop- athy 显示文摘 | Ramirez E Cartier L Rios M | 1998 | American Society for Microbiology1998，36，6： | 1 |
| 9 | Self-assembled monolayer- based piezoelectric flow immunosensor for the determination of canine immunoglobulin 显示文摘 | Arce L Zougagh M Arce C Moreno A Rios A Valcarcel M | 2007 | Biosensors and Bioelectronics2007，22，12： | 1 |
| 10 | Direct determination of biogenic amines in wine by integrating continuous flow clean-up and capillary electrophoresis with indirect UV detection显示文摘 | Arce L Rios A Valcarcel M | 1998 | J Chromatogr A1998，803，： | 1 |
| 11 | aroA gene PCR-RFLP diversity patterns in Haemophilus parasuis and Actinobacillus species显示文摘 | del Rio M L Martin C B Navas J | 2006 | Research in Veterinary Science2006，80，： | 1 |
| 12 | Expression analysis of the Ara-bidopsis peroxidase multigenic family显示文摘 | VALéRIO L DE MEYER M PENEL C | 2004 | Phytochemistry2004，65，10： | 1 |
| 13 | Posterior ure- thral stricture repair following trauma and pelvic fracture 显示文摘 | Rios E Martinez - Pineiro L Alvarez - Maestro M | 2014 | Arch Esp Urol2014，67，1： | 1 |
| 14 | Membrane fouling in cross - flow uhrafiltration of mineral oil assisted by pressuresed CO2显示文摘 | Rodriguez C Sarrade S Schrive L Dresch - Bazile M Paolucei D Rios G M | 2002 | Desilination2002，144，： | 1 |
| 15 | Value of fndirect hemagglutination and coagglutination tests for serotyping Haemophilus parasuis显示文摘 | Del Rio M L Gutierrez C B Rodriguez Ferri E F | 2003 | J Clin Microbiol2003，41，2： | 1 |
| 16 | Cucurbitacins as in- ducers of cell death and a rich source of potential anticancer com- pounds 显示文摘 | Rios J L Aud0jar I Escandell J M | 2012 | Curr Pharm Des2012，18，12： | 1 |
| 17 | 黄粉虫替代蛋白质饲料对太平洋白虾(凡纳滨对虾)消化性能的影响显示文摘试验旨在评估黄粉虫粉(MM)作为凡纳滨对虾养殖中蛋白质来源的可行性。饲料分为正常饲料和试验饲粮,试验饲料中包含正常饲料85%和MM 15%,两种饲料中均含有氧化铬0.5%作为惰性标记,试验采用表观消化率系数(ADC)对两种饲料进行检测。为评估MM消化价值,对虾饲料中采用鱼粉替代MM,替代比例分别为0%、25%、50%、75%和100%,在清水中饲养6周后,对生长参数和整个虾体成分进行评估。干物质ADC为45.9%,能量ADC为66.5%,粗蛋白质ADC为76.1%,必须氨基酸ADC为72%~86%。MM中蛋氨酸为第一限制性氨基酸。饲料中添加MM后,各组间对虾的体增重、特定生长率、采食量、饲料转化率、存活率和蛋白质合成率均无显著变化(P>0.05),虾体蛋白质含量无显著差异(P>0.05)。而随着鱼粉替代比例上升,虾体脂含量从1.13%升至1.88%。结果表明,黄粉虫粉可作为凡纳滨对虾饲料中的替代蛋白质饲料,但添加时应注意补充蛋氨酸。 | Panini R L Freitas L E L Guimarǎes A M Rios C da Silva M F O Vieira F N Fracalossi D M Samuels R I | 2017 | 饲料博览2017，0，7： | 1 |
| 18 | Polyphenolic composition of hazelnut skin显示文摘 | DEL RIO D CALANI L DALL'ASTA M | 2011 | Agricultural and Food Chemistry2011，59，： | 1 |
| 19 | Value of indi- rect hemagglutination and coagglutination tests for serotyping Haemophilus parasuis 显示文摘 | Del Rio M L Gutierrez C B Rodriguez Ferri E F | 2003 | J Clin Microbiol2003，41，2： | 1 |
| 20 | Constitutive arginine-dependent nitric oxide synthase activity in different organs of pea seedlings during plant development显示文摘 | CORPAS F J BARROSO J B CARRERAS A VALDERRAMA R PALMA J M LEON A M SANDALIO L M DEL RIO L A | 2006 | Planta2006，224，2： | 1 |
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