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| 1 | Antimicrobial activity,cytotoxicity,and phytochemical screening of Voacanga globosa(Blanco) Merr.leaf extract(Apocynaceae)显示文摘Objective:To determine the antibacterial,antifungal,antiprotozoal,cytotoxic,and phytochemical properties of ethanol extracts of leaves of Voacanga globosa(Blanco) Merr.(V.globosa). Methods:The extracts were tested against bacteria and fungus through disc diffusion assay; against protozoa through growth curve determination,antiprotozoal and cytotoxicity assays. Results:The extract revealed antibacterial activities,inhibiting the growth of Staphylococcus aureus,Bacillus cereus,Pseudomonas aeruginosa,Micrococcus luteus,and Salmonella typhimurium.Antifungal assay showed that it inhibited Candida albicans.The antiprotozoal assay against Trichomonas vaginalis and Entamoeba histolytica showed that V.globosa can inhibit the parasites,wherein the action can be comparable to metronidazole.With the in situ cell death detection kit.Trichomonas vaginalis and Entamoeba histolytica exposed to V.globosa leaf extract was observed to fluoresce simultaneously in red and yellow signals signifying apoptotic-like changes.Preliminary phytochemical screening revealed the chemical composition of plant extract containing alkaloids,saponins,2-deoxysugars,and hydrolysabie tannins.Conclusions: Thus,thus study provides scientific evidence on the traditional use of V.globosa leaf extract in treating microbial diseases.Further,the leaf extract can possibly be used to produce alternative forms of antimicrobials. | Pierangeli G Vital Windell L Rivera | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，10： | 5 |
| 2 | 显示文摘 | Ren Y Rivera J G He L | 2011 | BMC Biotcchnology2011，11，1： | 1 |
| 3 | Drug delivery to the inner ear:strategies and their therapeutic implications for sensorineural hearing loss显示文摘 | RIVERA T SANZ L CAMARERO G | 2012 | Curr Drug Deliv2012，9，： | 1 |
| 4 | Hydrodistillation of caraway by direct induction heating assisted by a magnetic field process 显示文摘 | Lagunez Rivera L Vilarem G | 2007 | Flavour and Fragrance Journal2007，22，： | 1 |
| 5 | Solidification of gray cast iron 显示文摘 | Rivera G L Boeri R E Sikora J A | 2004 | ScriptaMaterialia2004，，50： | 1 |
| 6 | Research advances in ductile iron solidification 显示文摘 | Rivera G L Boeri R E Sikora J A | 2003 | AFS Transactions2003，111，： | 1 |
| 7 | A psychometric evaluation of the Arm Motor Ability Test显示文摘 | O'Dell MW Kim G Rivera L | 2013 | J Rehabil Med2013，45，6： | 1 |
| 8 | Increasing day-length induces spring flushing of tropical dry forest trees in the absence of rain显示文摘 | Rivera G Elliott S Caldas L S | 2002 | Trees-Structure and Function2002，16，7： | 1 |
| 9 | Effects of age of introduction of complementary foods on iron status of breast - fed infants in Honduras显示文摘 | DEWEY K G COHEN R J RIVERA L L | 1998 | Am J Clin Nutr1998，67，5： | 1 |
| 10 | Development of an HPLC method for determination of diphenidol in plasma and its application in an oral multi-dose bioequivalence study in a healthy female Mexican population显示文摘 | HERNANDEZ J MARCELIN J G RIVERA L | 2005 | Pharm Biomed Anal2005，38，4： | 1 |
| 11 | Bone marrow recurrence after initial intensive treatment for childhood acute lymphoblastic leukemia显示文摘 | Rivera G K Zhou Y Hancock M L | 2005 | Cancer2005，103，2： | 1 |
| 12 | Drug delivery to the inner ear:strategies and their therapeutic implications for sensorineural hearing loss显示文摘 | Rivera T Sanz L Camarero G | 2012 | Curr Drug Deliv2012，9，3： | 1 |
| 13 | A revealing the solidification structure of nodular iron显示文摘 | Rivera G L Boeri R E Sikora J | 1995 | Cast metals1995，8，1： | 1 |
| 14 | JNarl显示文摘 | RELLING M V HANCOCK M L RIVERA G K | 1999 | Cancer lnst1999，91，3： | 1 |
| 15 | Persistence of lymphoblasts in bone marrow on day 15 and days 22 to 25 of remission induction predicts a dismal treatment outcome in children with acute lymphoblastic leukemia显示文摘 | Sandlund J T Harrison P L Rivera G | 2002 | Blood2002，100，1： | 1 |
| 16 | Alterations in ultrastructural morphology of two-cell bovine embryos produced in vitro and in vivo following a physiologically relevant heat shock显示文摘 | Rivera M Kelley K L Erdos G W | | 0，，06： | 1 |
| 17 | Alterations in ultrastructural morphology of two-cell bovine embryos produced in vitro and in vivo following a physiologically relevant heat shock 显示文摘 | RIVERA R M KELLEY K L ERDOS G W | 2003 | Biol Reprod2003，69，6： | 1 |
| 18 | Reorganization of microfilaments and microtubules by thermal stress in two-cell bovine embryos显示文摘 | RIVERA R M KELLEY K L ERDOS G W | 2004 | Biol Reprod2004，70，6： | 1 |
| 19 | Development of an HPLC method for determination of diphenidol in plasma and its application in an oral multi-dose bioequivalence study in a healthy female Mexican population显示文摘 | Hernandez J Marcelin-Jimenez G Rivera L | 2005 | J Pharm Biomed Anal2005，38，4： | 1 |
| 20 | Cognitive and executive functions in ADHD显示文摘 | Yanez G Romero H Rivera L | 2012 | Aetas Esp Psiquiatr2012，40，6： | 1 |
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