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| 1 | Long-term follow-up of distal intestinal obstruction syndrome in cystic fibrosis显示文摘AIM: To investigate the long-term follow-up of distal intestinal obstruction syndrome(DIOS) in Israeli cystic fibrosis(CF) patients.METHODS: This is a multi-center,comparative,retrospective study in which we reviewed the medical records of all CF patients from three major CF centers in Israel who were treated in the period from 1980 to 2012.Patients diagnosed with DIOS were defined as the study group.The patients were diagnosed with DIOS based on their clinical presentation and typical findings on either abdominal X-ray or computerized tomography scan.For the control group,CF patients with no DIOS were matched to the patients in the study group for age,sex,and cystic fibrosis transmembrane conductance regulator(CFTR) mutations.For both groups,the collected data included age,sex,CFTR genotype,weight,height,and body mass index.Clinical data included respiratory function tests in the last five years prior to the study,respiratory function test immediately before and after the DIOS event,number of hospitalizations,sputum culture results,and CFrelated conditions diagnosed according to the CF clinical practice guidelines.In the study group,data on the DIOS treatment and tendency for DIOS recurrence were also analyzed.RESULTS: The medical charts for a total of 350 CF patients were reviewed.Of the 350 CF patients,26(7.4%) were diagnosed with DIOS.The control group included 31 CF patients with no DIOS diagnosis.The mean follow-up period was 21.6 ± 8.2 years.The total of DIOS episodes in the follow-up period was 60.The distribution of DIOS episodes was as follows: 6/26(23.1%) study patients had one episode of DIOS intheir lifetime,7/26(26.9%) had two episodes,7/26(26.9%) had three episodes,and 6/26(23.1%) had four or more episodes.Compared to the control group,DIOS patients had a significantly higher incidence of meconium ileus in the past(65.4% vs 0%,respectively,P < 0.02),more Aspergillus spp.colonization(34.6% vs 3.2%,respectively,P < 0.02),and a higher number of hospitalizations due to respiratory exacerbations(8.6 vs 6.2 mean total hospitalizations per follow-up period,respectively,P < 0.02).No other significant differences were found between the control and study groups.The conservative treatment of DIOS,which mainly includes hydration and stool softeners,was successful in 82% of the episodes.The survival rate was similar for both groups.CONCLUSION: CF patients with DIOS suffer from recurrent hospitalizations and airway pathogen acquisition.Although recurrence of DIOS is common,conservative treatment is successful in most patients. | Moran Lavie Tzipora Manovitz Daphna Vilozni Sarina Levy-Mendelovich Ifat Sarouk Ilana Weintraubv David Shoseyov Malena Cohen-Cymberknoh Joseph Rivlin Ori Efrati | 2015 | World Journal of Gastroenterology2015，21，1： | 10 |
| 2 | Vulvar granular cell tumor显示文摘Granular cell tumors are rare,usually benign,soft tissue neoplasms of neural origin.They occur more often in females than males,the peak age incidence is in the fourth through fifth decades.They can occur anywhere in the body with up to 15% situated in the vulva.The commonest presentation is as an asymptomatic mass.Microscopic findings are usually sufficient,but immunohistochemistry can also be helpful in confirming the diagnosis.The vulvar tumors are benign in 98% of cases with 2% reported as malignant.In this case report we describe a woman with a granular cell tumor confirmed by biopsy who underwent excision of the mass but with focal extension to the resection margin on microscopy.Our recommendation of re-excision was declined.Since it is not uncommon with these tumors to find groups of tumor cells extending beyond the macroscopic limits of growth,we conclude that it is advisable to have margins assessed intraoperatively by frozen section such that further excision can be performed for positive margins.Our patient has been followed for 18 mo without recurrence,should the tumor recur,re-excision,with frozen section control,is indicated.Recurrence rates are reported as 2%-8% with clear margins and 20% with positive margins. | Michel E Rivlin G Rodney Meeks Mohamed A Ghafar Jack R Lewin | 2013 | World Journal of Clinical Cases2013，1，4： | 2 |
| 3 | Large elastic deformations of isotropic materials, part 7,Experiments on the Deformations of rubber显示文摘 | D W Saunders | 1951 | Philosophical Transactions of Royal Society1951，243，： | 1 |
| 4 | Objective clinical assessment of motor function after experimental spinal cord injury in rat显示文摘 | Rivlin AS Tator CH | 1997 | J Neurosurg1997，47，5： | 1 |
| 5 | The hydrodynamics of non-newtonian fluids显示文摘 | Rivlin R S | 1948 | Proc Roy Soc A1948，193，： | 1 |
| 6 | Visual stimulationreverses the directional preference of direction-selective retinalganglion cells 显示文摘 | Rivlin - Etzion M Wei Wei Feller MB | 2012 | Neuron2012，76，3： | 1 |
| 7 | Finite Element Analysis of Load-Defec- tion and characteristics of compressed rubber components for vibration control devices显示文摘 | Lee B S Rivlin E I | 1996 | Journal of Mechanical De- sign1996，34，3： | 1 |
| 8 | Mean shift tracking with multiple references color histograms显示文摘 | Leichter I Lindenbaum M Rivlin E | 2010 | Computer Vision and Image Understanding(S1077-3142)2010，114，3： | 1 |
| 9 | Stress-deformation relations for isotropic materials显示文摘 | Rivlin R S | 1955 | J Rational Mech Anal1955，4，： | 1 |
| 10 | Fast geodesic active contours显示文摘 | Roman Goldenberg Ron Kimmel Ehud Rivlin | 2001 | IEEE Transactions on Image Processing2001，10，10： | 1 |
| 11 | Objective clinical assessment of motorfunction after experimental spinal cord injury in the rat显示文摘 | Rivlin AS Tator CH | 1977 | J Neurosurg1977，47，4： | 1 |
| 12 | Integrity bases for a symmetric tensor and a vector- the crystal classes显示文摘 | Smith G F Smith M M Rivlin R S | | 0，，： | 1 |
| 13 | Medical progress: riboflavin metabolism显示文摘 | Rivlin R S | 1970 | N Engl J Med1970，283，： | 1 |
| 14 | Mean shift tracking with multiple references color histograms显示文摘 | Leichter I Lindenbaum M Rivlin E | 2010 | Computer Vision and Image Understanding2010，114，3： | 1 |
| 15 | Large elastic deformations of isotropic materials I Fundamental concepts显示文摘 | Rivlin R S | 1948 | Phil Trans Soc1948，240，： | 1 |
| 16 | Flow of a viscoelastic fluid between eccentric rotating cylinders and related problems显示文摘 | KAZAKIA J Y RIVLIN R S | 1977 | Rheol Acta1977，16，： | 1 |
| 17 | Mean shift tracking with multiple reference color histograms 显示文摘 | Leichter I Lindenbaum M Rivlin E | 2010 | Computer Vision and Image Understanding2010，114，3： | 1 |
| 18 | Structural analysis of hypertext:identifying hierarchies and Useful metrics显示文摘 | Botafogo R Rivlin E Shneiderman B | | ACM Trans Inf Sys0，10，： | 1 |
| 19 | Mutations in the p53 tumor suppressor gene: important milestones at the various steps of tumorigenesis显示文摘 | Noa Rivlin Rn Brosh Moshe Oren | 2011 | Genes Cancer2011，2，4： | 1 |
| 20 | Objective clinical assessment of motor function after experimental spinal cord injury in rat显示文摘 | Tator CH | 1997 | J Neurosurg1997，47，2： | 1 |
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