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| 1 | Immunoexpression of cyclooxygenase-2 in primary gastric carcinomas and lymph node metastases显示文摘AIM: To evaluate immunoexpression of cyclooxygenase-2 (COX-2) in primary gastric carcinomas and respective lymph node metastases. METHODS: Immunohistochemistry to analyze COX-2 expression was performed on tissue microarray slices obtained from 36 specimens of gastrectomy and satellite lymph nodes from patients with gastric carcinoma. RESULTS: Immunostaining was seen in most cases, and COX-2 expression was higher in lymph node me-tastases than in corresponding primary gastric tumors of intestinal, diffuse and mixed carcinomas, with a statistically signif icant difference in the diffuse histotype (P = 0.0108). CONCLUSION: COX-2 immunoexpression occurs frequently in primary gastric carcinomas, but higher expression of this enzyme is observed in lymph node metastases of the diffuse histotype. | Paulo RC Almeida Francisco VA Ferreira Cássio C Santos Francisco D Rocha-Filho Raul RP Feitosa Esther AA Falco Belise K Cavada Roberto CP Lima-Júnior Ronaldo A Ribeiro | 2012 | World Journal of Gastroenterology2012，18，8： | 14 |
| 2 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 3 | Sequential assembly and polymerization of the polyprenol-linked pentasacchariderepeating unit of the Xanthan polysaccharide in Xanthomonas campestris显示文摘 | Luis I Roberto O C Marcelo A D | 1993 | Journal of Bacteriology1993，175，9： | 1 |
| 4 | Robust and efficient authentication of video stream broadcasting显示文摘 | GABRIELE O STEFANO C ROBERTO D P | 2011 | ACM Transactions on Information and System Security (TISSEC)2011，14，1： | 1 |
| 5 | Solidstate fermentation for xylanse production by thermoascus aurantiaus using response surface methodology 显示文摘 | De O Souza M C Roberto I C | 1999 | Apply Microbiolbiotachnol1999，，52： | 1 |
| 6 | Incremental Value of Perfusion over Wall‐Motion Abnormalities with the Use of Dobutamine–Atropine Stress Myocardial Contrast Echocardiography and Magnetic Resonance Imaging for Detecting Coronary Artery Disease显示文摘 | Sandra Nivea dos Reis Saraiva Falc?o Carlos Eduardo Rochitte Wilson Mathias Junior Luiz Quaglia Pedro Alves Lemos Jo?o César Nunes Sbano José Antonio Franchini Ramires Roberto Kalil Filho Jeane Mike Tsutsui | 2012 | Echocardiography2012，，： | 1 |
| 7 | Self-propagating combustion synthesis and plasma spraying deposition of TiC/Fe powders 显示文摘 | ROBERTA L ROBERTO O GIACOMO C | 2003 | Ceramics International2003，29，5： | 1 |
| 8 | Adsorption of fluoride from water solution on bone char显示文摘 | NAHUM A M C ROBERTO L R RAUL O P | 2007 | Industrial Engineering Chemistry Research2007，46，26： | 1 |
| 9 | Incidence and risk factors for agranulocytosis in Latin American countries—the Latin Study显示文摘 | Nelson Hamerschlak Eliane Maluf Alexandre Biasi Cavalcanti álvaro Avezum Júnior José Eluf-Neto Roberto Passeto Falc?o Irene Gyongyvér Heidemarie Lorand-Metze Daniel Goldenberg Cézar Leite Santana Daniela de Oliveira Werneck Rodrigues Leny Nascimento da Mo | 2008 | European Journal of Clinical Pharmacology2008，，9： | 1 |
| 10 | Sequential assembly and polymerization of the polyprenol-linked pentasaccharide repeating unit of the Xanthan polysaccharide in Xanthomonas campestris显示文摘 | Luis I Roberto O C Marcelo A D | 1993 | Journal of Bacteriology1993，175，9： | 1 |
| 11 | Concurrent round-robin-based dispatching schemes for Clos-network switches显示文摘 | Eiji O Jing Zhigang Roberto R C | 2002 | IEEE/ACM Transactions on Networking2002，10，6： | 1 |
| 12 | Solidstate fermentation for xylanse production by thermoascus aurantiaus using response surface methodology 显示文摘 | De O Souza M C Roberto I C | 1999 | Apply Microbiolbiotachnol1999，52，： | 1 |
| 13 | Solid- state fermentation for xylanase production by Thermoascus aurantiacus using response surface methodology显示文摘 | Souza M C de O Roberto I C Milagres A M F | 1999 | Appl Microbiol Biotechnol1999，52，6： | 1 |
| 14 | Self-propagating combustion synthesis and plasma spraying deposition of TiC/Fe powders显示文摘 | Roberta L Roberto O Giacomo C | 2003 | Ceramics International2003，29，5： | 1 |
| 15 | Self-propagating com- bustion synthesis and plasma spraying deposition of TiC/Fe powders 显示文摘 | Roberta L Roberto O Giacomo C | 2003 | Ceramics International2003，29，5： | 1 |
| 16 | Risk of fracture in celiac disease:Gender,dietary compliance,or both?显示文摘AIM:To determine the incidence of peripheral fractures in patients with celiac disease (CD) and the effect of treatment on fracture risk.METHODS:We compared the incidence and risk of peripheral fractures before and after diagnosis between a cohort of 265 patients who had been diagnosed with CD at least 5 years before study entry and a cohort of 530 age-and sex-matched controls who had been diagnosed with functional gastrointestinal disorders.Data were collected through in-person interviews with an investigator.The overall assessment window for patients was 9843 patient-years (2815 patient-years after diagnosis).RESULTS:Compared with the control group,the CD cohort showed significantly higher incidence rate and risk of first peripheral fracture before diagnosis [adjusted hazard ratio (HR):1.78,95% CI:1.23-2.56,P < 0.002] and in men (HR:2.67,95% CI:1.37-5.22,P < 0.004).Fracture risk was significantly associated with the classic CD presentation with gastrointestinal symptoms (P < 0.003).In the time period after diagnosis,the risk of fractures was comparable between the CD cohort and controls in both sexes (HR:1.08,95% CI:0.55-2.10 for women;HR:1.57,95% CI:0.57-4.26 for men).CONCLUSION:CD patients have higher prevalence of fractures in the peripheral skeleton before diagnosis.This is associated with male sex and classic clinical presentation.The fracture risk was reduced after the treatment. | María Inés Pinto Sánchez Adriana Mohaidle Andrea Baistrocchi Dolores Matoso Horacio Vázquez Andrea González Roberto Mazure Evangelina Maffei Guillermina Ferrari Edgardo Smecuol Adriana Crivelli Juan Andrés de Paula Juan C Gómez Silvia Pedreira Eduardo Maurio Julio César Bai | 2011 | World Journal of Gastroenterology2011，17，25： | 1 |
| 17 | The successive projections algorithm for variable selection in spectroscopic multicomponent analysis显示文摘 | Mário César Ugulino Araújo Teresa Cristina Bezerra Saldanha Roberto Kawakami Harrop Galv?o Takashi Yoneyama Henrique Caldas Chame Valeria Visani | 2001 | Chemometrics and Intelligent Laboratory Systems2001，，2： | 1 |
| 18 | Single solid phaseextraction method for the simultaneous analysis of polar and nonpolarpesticides in urine samples by gas chromatography and ultrahigh pressure liquid chromatography coupled to tandem massspectrometry显示文摘 | Rocío C R JoséL F M Roberto R G | 2011 | Talanta2011，85，18： | 1 |
| 19 | Adsorption of fluoride from water solution on bone char显示文摘 | NAHUM A M C ROBERTO L R RAUL O P | 2007 | Industrial & Engineering Chemistry Research2007，46，26： | 1 |
| 20 | Round-Robin Selection with Adaptable-size Frame in a Combined Input-crosspoint Buffered Switch显示文摘 | Roberto R C Eiji O | 2003 | IEEE Communications Letters2003，7，11： | 1 |
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