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| 1 | International NeuroAIDS: prospects of HIV-1 associated neurological com-plications显示文摘Neurological complications associated with HIV-1/AIDS are being recognized with a high frequency that parallels the increased number of AIDS cases. The early infiltration by HIV-1 into the nervous system can cause primary and/or secondary neurological complications. The most common neurocognitive disorder is AIDS Dementia Complex (ADC). In developing countries of Asia the three most opportunistic infections are tuberculosis (TB), cryptococcosis, and Pneumocystis carinii pneumonia. Therefore, it is expected that secondary neurological complications due to TB and cryptococcosis will be the most common cause of morbility and mortality in HIV-1/AIDS cases in China. Research of NeuroAIDS in China is necessary to understand the impact and the biology of HIV-1 in the nervous system. Future studies would include, the molecular epidemiology and the description of opportunistic infections associated to HIV-1; the neuropathological description of primary and secondary HIV-1 complications in different groups; the HIV-1 neurot- ropism and immune response studies for China’s unique HIV-1 strains and recombinant forms derived from the nervous system, including experimental models such as the use of transgenic rats; and the study of potential resistant virus, primarily when the anti-retroviral therapy (ART) has not full access in the brain. | J Roberto TRUJILLO Gilberto JARAMILLO-RANGEL Marta ORTEGA-MARTINEZ Augusto C PENALVA de OLIVEIRA Jose E VIDAL Joseph BRYANT Robert C GALLO | 2005 | Cell Research2005,15,11: | 4 |
| 2 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010,16,25: | 4 |
| 3 | Listeria monocytogenes following orthotopic liver transplantation:Central nervous system involvement and review of the literature显示文摘Listeria monocytogene is a well-recognized cause of bacteremia in immunocompromised individuals,including solid organ transplant recipients,but has been rarely reported following orthotopic liver transplantation. We describe a case of listeria meningitis that occurred within a week after liver transplantation. The patient developed a severe headache that mimicked tacrolimus encephalopathy,and was subsequently diagnosed with listeria meningitis by cerebrospinal fluid culture. The infection was successfully treated with three-week course of intravenous ampicillin. Recurrent hepatitis C followed and was successfully treated with interferon alfa and ribavirin. Fourteen cases of listeriosis after orthotopic liver transplantation have been reported in the English literature. Most reported cases were successfully treated with intravenous ampicillin. There were four cases of listeria meningitis,and the mortality of them was 50%. Early detection and treatment of listeria meningitis are the key to obtaining a better prognosis. | Shugo Mizuno Ivan R Zendejas Alan I Reed Robin D Kim Richard J Howard Alan W Hemming Denise C Schain Consuelo Soldevila-Pico Roberto J Firpi Shiro Fujita | 2007 | World Journal of Gastroenterology2007,13,32: | 2 |
| 4 | Producing gas from its source显示文摘 | Boyer C Kieschnick J Roberto S R | 2006 | Oilfield Review2006,18,3: | 1 |
| 5 | A method for calibration and validation subset partitioning显示文摘 | ROBERTO K H G MARIO C U A GLEDSON E J | 2005 | Talanta2005,67,4: | 1 |
| 6 | The successive projections algorithm for spectral variable selection in classification problems 显示文摘 | Marcio J C P Roberto K H G Mario C U A | 2005 | Chemometrics and Intelligent Laboratory Systems2005,78,: | 1 |
| 7 | Incidence and risk factors for agranulocytosis in Latin American countries—the Latin Study显示文摘 | Nelson Hamerschlak Eliane Maluf Alexandre Biasi Cavalcanti álvaro Avezum Júnior José Eluf-Neto Roberto Passeto Falc?o Irene Gyongyvér Heidemarie Lorand-Metze Daniel Goldenberg Cézar Leite Santana Daniela de Oliveira Werneck Rodrigues Leny Nascimento da Mo | 2008 | European Journal of Clinical Pharmacology2008,,9: | 1 |
| 8 | Vision-Based Relative Navigation for Formation Flying of Spacecraft显示文摘 | Roberto A John L C John L J | 2000 | AIAA Guidance Navigation and Control Conference and Exhibit2000,,: | 1 |
| 9 | Adaptive sliding mode control of autonomous underwater vehicles in the dive plane 显示文摘 | Roberto C Papoulias F A Healey A J | 1990 | IEEE Journal of Oceanic Engineering1990,15,3: | 1 |
| 10 | Statistical screening method forselection of important variables on xyhtol biosynthesis from rice straw hydrolysate by Candida guilliermon dii FTI 20037 显示文摘 | Silva C J Roberto I C | 1999 | Biotechnol Tech1999,13,: | 1 |
| 11 | Generational Accounting in the UK显示文摘 | Roberto C J Sefton L J Kotlikoff | 2000 | Economic Journal2000,,110: | 1 |
| 12 | The redox chemistry of the Alzheimer's disease amyloid β-peptide 显示文摘 | DANIELLE G S ROBERTO C KEVIN J B | 2007 | Biochimica et Biophysiea Acta2007,1768,: | 1 |
| 13 | The selective peroxisomal proliferator-activated receptor-gamma agonist has an additive effect on plaque regression in combination with simvastatin in experimental atherosclerosis in vivo study by high-resolution magnetic resonance imaging显示文摘 | ROBERTO C OSENDE J I FALLON J T | 2004 | J Am Coll Cardiol2004,43,: | 1 |
| 14 | Evolving concepts in the triad of atherosclerosis,inflammation and thrombosis显示文摘 | Roberto C Hutter R Badimon J | 2004 | J Thromb Thromb2004,17,: | 1 |
| 15 | Adaptation of the van Genuchten expression to the effects oftemperature and density for compacted ben- tonites 显示文摘 | ABEL C J MARfA V V ROBERTO G E | 2009 | Applied Clay Science2009,42,: | 1 |
| 16 | Mesenteric vasoconstriction triggers nitric oxide overproduction in the superior mesenteric artery of portal hypertensive rats显示文摘 | Ming-Hung Tsai Yasuko Iwakiri Gregory Cadelina William C Sessa Roberto J Groszmann | 2003 | Gastroenterology2003,,5: | 1 |
| 17 | Moisture diffusivity coefficient and convective drying, mdelling of nmrta ( Ugni molinae Turcz) : influence of temperature and vacuum on drying kinetics 显示文摘 | Kong A H Zambra C E Agu~ro J E Antonio V G Roberto Lemus- Mondaca | 2012 | Food and Bioprocess Technology2012,6,4: | 1 |
| 18 | Project management offices: a case of knowledge-based archetypes 显示文摘 | Kevin C Desouzaa J Roberto Evaristo | 2006 | International Journal of Information Management2006,26,5: | 1 |
| 19 | Adsorption of heavy metal ion from aqueous single metal solution by chemically modified sugarcane bagasse显示文摘 | Osvaldo Karnitz Leandro Vinicius Alves Gurgel Júlio César Perin de Melo Vagner Roberto Botaro Tania Márcia Sacramento Melo Rossimiriam Pereira de Freitas Gil Laurent Frédéric Gil | 2006 | Bioresource Technology2006,,6: | 1 |
| 20 | Possibilities and limitations in miniaturized sensor design for uric acid 显示文摘 | Roberto B Chen C H Alonso J | 1998 | Analyst1998,123,: | 1 |