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126篇 您的检索式:作者名="ROSSY W"
    题名 作者 年代 出处 被引量
1Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells显示文摘AIM:To investigate effects of iron on oxidative stress, heme oxygenase-1(HMOX1)and hepatitis C viral(HCV) expression in human hepatoma cells stably expressing HCV proteins. METHODS:Effects of iron on oxidative stress,HMOX1, and HCV expression were assessed in CON1 cells. Measurements included mRNA by quantitative reverse transcription-polymerase chain reaction,and protein levels by Western blots. RESULTS:Iron,in the form of ferric nitrilotriacetate,increased oxidative stress and up-regulated HMOX1 gene expression.Iron did not affect mRNA or protein levels of Bach1,a repressor of HMOX1.Silencing the up-regulation of HMOX1 nuclear factor-erythroid 2-related factor 2(Nrf2)by Nrf2-siRNA decreased FeNTA-mediated up-regulation of HMOX1 mRNA levels.These iron effects were completely blocked by deferoxamine(DFO).Iron also significantly decreased levels of HCV core mRNA and protein by 80%-90%, nonstructural 5A mRNA by 90%and protein by about 50%in the Con1 full length HCV replicon cells, whereas DFO increased them. CONCLUSION:Excess iron up-regulates HMOX1 and down-regulates HCV gene expression in hepatoma cells.This probably mitigates liver injury caused by combined iron overload and HCV infection.Wei-Hong Hou Lisa Rossi Ying Shan Jian-Yu Zheng Richard W Lambrecht Herbert L Bonkovsky 2009World Journal of Gastroenterology2009,15,36:5
2Impact of market restructing on power systems operation显示文摘Dunn W Rossi M Avaramovic B 1995IEEE Computer Application in Power Engineering1995,8,1:2
3Geostatistics and geo- graphic information systems in applied insect ecology 显示文摘Liebhold A M Rossi R E Kemp W P 1993An nual Review of Entomology1993,38,1:1
4Characterization and prognosis value of persistent hyponatremia in patients with severe heart failure in ESCAPE trial显示文摘Georghiade M Rossi J Cotts W 2007Arch Intern Med2007,167,:1
5The ettect of isoflurane on neutrophil seleetin and beta (2)-integrin activation in vitro显示文摘de Rossi LW Horn NA Buhre W 2002Anesth Analg2002,95,3:1
6Rapid prototyped porous nickel-titanium scaffolds as bone substitutes 显示文摘HOFFMANN W BORMANN T ROSSI A 2014Journal of Tissue Engineering2014,5,20:1
7Optimization of titanium cutting by factorial analysis of the pulsed Nd :YAG laser parameters 显示文摘Almeida I A Rossi W de Lima MSF 2006Materials Processing Technology2006,,179:1
8Geostatistics and geographic information systems in applied insect ecolo- gy显示文摘LIEBHOLD A M ROSSI R E KEMKP W P 1993Annu Rev Entomol1993,38,:1
9Thymic atrophy in murine acute graft-versus-host disease is effected by impaired cell cycle progression of host pro-T and pre-T cell 显示文摘 Rossi S Piali L 2000Blood2000,26,1:1
10Difficult problems in thyroid surgery显示文摘PRINZ R A ROSSI H L KIM A W 2002Curr Probl Surg2002,39,1:1
11Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE Trial显示文摘Gheorghiade M Rossi JS Cotts W 2007Arch Intern Med2007,167,18:1
12From marrow to brain: expression of neuronal phenotypes in adult mice显示文摘Brazelton T R Rossi F W M Keshet G I 2000Science2000,290,:1
13Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE Trial显示文摘Gheorghiade M Rossi JS Cotts W 2007J Am Coll Cardiol2007,167,18:1
14Geostatistics and geographic information systems in applied insect ecology 显示文摘LIEBHOLD A M ROSSI R E KEMP W P 1993Annual Review of Entomology1993,38,:1
15Noninvasive evaluation of vaginal fibrosis following radiotherapy for gynecologic ma lignancies: A feasibility study with ultrasound B-mode and Na kagami parameter imaging显示文摘Yang X Rossi P Bruner D W 2013Medical physics2013,40,2:1
16Stochastic modeling of total suspended solids (TSS) in urban areas during rain events显示文摘ROSSI L KREJCI V RAUCH W 2005Water Researeh2005,39,17:1
17Geostatistics and geographic information system in applied insect ecology 显示文摘Liebhold A Rossi R Kemp W 1993Annual Review of Entomology1993,38,:1
18The Futile Search for the Perfect Shoe Fit 显示文摘Rossi W A 1988Journal of Testing and Evaluation1988,16,4:1
19Geostatistics and geographic information systems in applied insect ecology显示文摘Liebhold A M Rossi R E Kemp W P 1993Annu Rev Entomo1993,38,:1
20The operation and modeling of transmission line transformers using a referral method显示文摘Granean P N Rossi J O Smith P W 1999Rev Sol Instrum1999,70,7:1
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