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| 1 | Influence of unrecorded alcohol consumption on liver cirrhosis mortality显示文摘Unrecorded alcohol includes illegally distributed alcohol as well as homemade or surrogate alcohol which is unintended for consumption by humans(e.g.,cosmetics containing alcohol).The highest unrecorded alcohol consumption occurs in Eastern Europe and some of these countries have an over proportional liver cirrhosis mortality.Compounds besides ethanol have been hypothesized as being responsible for this observation.On the other hand,chemical investigations were unable to prove that unrecorded alcohol regularly contains contaminants above toxicological thresholds.However,illegally produced spirits regularly contain higher percentages of alcohol(above 45%by volume),but for considerably less costs compared with licit beverages,potentially causing more problematic patterns of drinking.In this review,it is investigated whether patterns of drinking rather than product composition can explain the liver cirrhosis mortality rates.Statistical examination of World Health Organization country data shows that the originally detected correlation of the percentage of unrecorded alcohol consumption and liver cirrhosis mortality rates disappears when the data is adjusted for the prevalence of heavy episodic drinking.It may be concluded that there is currently a lack of data to demonstrate causality between the composition of illicit spirits(e.g.,higher levels of certain contaminants in home-produced products)and liver toxicity on a population scale.Exceptions may be cases of poisoning with antiseptic liquids containing compounds such as polyhexamethyleneguanidine,which were reported to be consumed as surrogate alcohol in Russia,leading to an outbreak of acute cholestatic liver injury,histologically different from conventional alcoholic liver disease. | Dirk W Lachenmeier Yulia B Monakhova Jürgen Rehm | 2014 | World Journal of Gastroenterology2014，20，23： | 10 |
| 2 | Accumulation of colbalt zinc and mang nese by the estuarine green microalgae chlorella salina immobilize in alginatemicrobeads显示文摘 | Rehm H J | 1992 | Environ Sci Technol1992，26，1： | 1 |
| 3 | Alteration of mammalian cell metabolism by dynamic nutrient feeding显示文摘 | Zhou W C Rehm J Europa A | 1997 | Cytotechnology1997，24，2： | 1 |
| 4 | Degradation of stachyose, raffinose, meli- biose and sucrose by different tempe--producing Rhizopus fungi显示文摘 | Rehms H Barz W | 1995 | Appl Microbiol Biotechnol1995，44，： | 1 |
| 5 | Carcinogenicity of acetaldehyde in alcoholic beverages:risk assessment outside ethanol metabolism显示文摘 | LACHENMEIER D W KANTERES F REHM J | 2009 | Addiction (Abingdon England)2009，104，4： | 1 |
| 6 | High viable cell concentration fed-batch culture of hybridoma cells through on-line nutrient feeding显示文摘 | Zhou W C Rehm J Hu W S | 1995 | Biotechnol Bioeng1995，46，6： | 1 |
| 7 | Diagnosis of clinical vitamin B1 deficiency in cattle 显示文摘 | REHM W F ZEROBIN K CHRISTELLER S | 1971 | Berl Mtinch Tiearar Wochenschr1971，84，： | 1 |
| 8 | Cadmium carcinogenesis in male Wistar rats: dose-response analysis of tumor induction in the prostate and testes and at the injection site显示文摘 | Waalkes M P Rehm S Riggs C W Bare R M Devor D E Poirier LA Wenk M L Henneman J R Balaschak M S | | Cancer Res0，48，16： | 1 |
| 9 | Alteration of mamma- lian cell metabolism by dynamic nutrient feeding显示文摘 | Zhou W Rehm J Europa A | 1997 | Cy- totechnology1997，24，2： | 1 |
| 10 | Nitrogen and sulfur effects onthe yield and quality of com grown for grain and silage显示文摘 | OMearry M J Rehm G W | 1990 | Journal of Production Agriculture1990，3，： | 1 |
| 11 | High viable cell concentration fed-batch cultures of hybridoma through on-line nutrient feeding 显示文摘 | Zhou W C Rehm J Hu W S | 1995 | Biotechnol Bioeng1995，47，： | 1 |
| 12 | Alcohol use disorders in EU countries and Norway: an overview of the epidemiology 显示文摘 | Rehm J Room R van den Brink W | 2005 | Eur Neuro- psychopharmacol2005，15，4： | 1 |
| 13 | Genotype x environment interactions with- in iron deficiency chlorosis-tolerant soybean genotypes显示文摘 | Naeve S L Rehm G W | 2006 | Agron- omy Journal2006，98，： | 1 |
| 14 | Application of phosphorus and sulphur on irrigated alfalfa显示文摘 | Rehm G W | 1987 | Agronomy Journal1987，79，： | 1 |
| 15 | Nitrogen and sulfur effects on the yield and quality of corn grown for grain and silage显示文摘 | O'learry M J Rehm G W | 1990 | Journal of Production Agriculture1990，3，1： | 1 |
| 16 | Sulfur response by alfalfa on a sulfur-deficient soil显示文摘 | Seim E C Caldwell A C Rehm G W | 1969 | Agronomy Journal1969，61，： | 1 |
| 17 | High viable cell concentration fedbatch cultures of hybridoma cells through on-line nutrient feeding显示文摘 | Zhou W Rehm J Hu W S | | 0，，06： | 1 |
| 18 | A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9activation显示文摘 | Würstle ML Rehm M | 2014 | J Biol Chem2014，289，26： | 1 |
| 19 | Accumulation of cobalt zinc and manganese by the estuarine green microalgae chlorella salina immobilized in alginate microbeads显示文摘 | GEOFFREY W REHM H J | 1992 | Environ Sci Technol1992，26，5： | 1 |
| 20 | Vertical integration in supply chains:Driving forces and consequences for a manufacturer's downstream integration显示文摘 | Guan W Rehme J | 2012 | Supply Chain Management:An International Journal2012，17，2： | 1 |
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